1,720,963 research outputs found
Supplemental Material, DS1_VET_10.1177_0300985818798094 - Tumor Thickness and Modified Clark Level in Canine Cutaneous Melanocytic Tumors
No full textSupplemental Material, DS1_VET_10.1177_0300985818798094 for Tumor Thickness and Modified Clark Level in Canine Cutaneous Melanocytic Tumors by Serenella Silvestri, Ilaria Porcellato, Luca Mechelli, Laura Menchetti, Sofia Rapastella, and Chiara Brachelente in Veterinary Pathology</p
Supplemental Material, DS1_VET_10.1177_0300985818808530 - FoxP3 and IDO in Canine Melanocytic Tumors
No full textSupplemental Material, DS1_VET_10.1177_0300985818808530 for FoxP3 and IDO in Canine Melanocytic Tumors by Ilaria Porcellato, Chiara Brachelente, Livia De Paolis, Laura Menchetti, Serenella Silvestri, Monica Sforna, Gaia Vichi, Selina Iussich, and Luca Mechelli in Veterinary Pathology</p
sj-pdf-2-vet-10.1177_03009858231207025 – Supplemental material for Vulvo-vaginal epithelial tumors in mares: A preliminary investigation on epithelial-mesenchymal transition and tumor-immune microenvironment
No full textSupplemental material, sj-pdf-2-vet-10.1177_03009858231207025 for Vulvo-vaginal epithelial tumors in mares: A preliminary investigation on epithelial-mesenchymal transition and tumor-immune microenvironment by Federico Armando, Ilaria Porcellato, Livia de Paolis, Samanta Mecocci, Benedetta Passeri, Małgorzata Ciurkiewicz, Luca Mechelli, Chiara Grazia De Ciucis, Marzia Pezzolato, Floriana Fruscione, Chiara Brachelente, Vittoria Montemurro, Katia Cappelli, Christina Puff, Wolfgang Baumgärtner, Alessandro Ghelardi and Elisabetta Razzuoli in Veterinary Pathology</p
sj-xlsx-1-vet-10.1177_03009858231207025 – Supplemental material for Vulvo-vaginal epithelial tumors in mares: A preliminary investigation on epithelial-mesenchymal transition and tumor-immune microenvironment
No full textSupplemental material, sj-xlsx-1-vet-10.1177_03009858231207025 for Vulvo-vaginal epithelial tumors in mares: A preliminary investigation on epithelial-mesenchymal transition and tumor-immune microenvironment by Federico Armando, Ilaria Porcellato, Livia de Paolis, Samanta Mecocci, Benedetta Passeri, Małgorzata Ciurkiewicz, Luca Mechelli, Chiara Grazia De Ciucis, Marzia Pezzolato, Floriana Fruscione, Chiara Brachelente, Vittoria Montemurro, Katia Cappelli, Christina Puff, Wolfgang Baumgärtner, Alessandro Ghelardi and Elisabetta Razzuoli in Veterinary Pathology</p
A retrospective investigation on canine papillomavirus 1 (CPV1) in oral oncogenesis reveals dogs are not a suitable animal model for high-risk HPV-induced oral cancer.
No full textCPV1 (also called COPV) is a papillomavirus responsible for oral papillomatosis in young dogs. The involvement of this viral type in oral oncogenesis has been hypothesized in oral squamous cell carcinomas (SCCs), but has never been investigated in other neoplastic and hyperplastic oral lesions of dogs. Aim of this study was to investigate the presence of CPV1 in different neoplastic and hyperplastic lesions in order to assess its role in canine oral oncogenesis; according to the results obtained, a second aim of the study was to define if the dog can be considered a valid animal model for oral high risk HPV-induced tumors. Eighty-eight formalin-fixed, paraffin-embedded (FFPE) canine oral lesions including 78 oral tumors (papillomas, SCCs, melanomas, ameloblastomas, oral adenocarcinomas) and 10 hyperplastic lesions (gingival hyperplasia) were investigated with immunohistochemistry for the presence of papillomavirus L1 protein and with Real-Time PCR for CPV1 DNA. RT-PCR for RNA was performed on selected samples. All viral papillomas tested were positive for immunohistochemistry and Real-time PCR. In 3/33 (10%) SCCs, viral DNA was demonstrated but no viral RNA could be found. No positivity was observed both with immunohistochemistry and Real-Time PCR in the other hyperplastic and neoplastic lesions of the oral cavity of dogs. Even though the finding of CPV1 DNA in few SCCs in face of a negative immunohistochemistry could support the hypothesis of an abortive infection in the development of these lesions, the absence of viral RNA points out that CPV1 more likely represents an innocent bystander in SCC oncogenesis. The study demonstrates a strong association between CPV1 and oral viral papillomas whereas viral contribution to the pathogenesis of other oral lesions seems unlikely. Moreover, it suggests that a canine model of CPV1 infection for HPV-induced oncogenesis could be inappropriate
Data_Sheet_1_Model order reduction for optimality systems through empirical gramians.pdf
No full textIn the present article, optimal control problems for linear parabolic partial differential equations (PDEs) with time-dependent coefficient functions are considered. One of the common approach in literature is to derive the first-order sufficient optimality system and to apply a finite element (FE) discretization. This leads to a specific linear but high-dimensional time variant (LTV) dynamical system. To reduce the size of the LTV system, we apply a tailored reduced order modeling technique based on empirical gramians and derived directly from the first-order optimality system. For testing purpose, we focus on two specific examples: a multiobjective optimization and a closed-loop optimal control problem. Our proposed methodology results to be better performing than a standard proper orthogonal decomposition (POD) approach for the above mentioned examples.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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