113 research outputs found
sj-docx-1-psx-10.1177_00323217241229316 – Supplemental material for ‘No Participation Without Representation’: The Impact of Descriptive and Substantive Representation on the Age-Related Turnout Gap
No full textSupplemental material, sj-docx-1-psx-10.1177_00323217241229316 for ‘No Participation Without Representation’: The Impact of Descriptive and Substantive Representation on the Age-Related Turnout Gap by Davide Angelucci, Luca Carrieri and Marco Improta in Political Studies</p
Towards a Collaborative Filtering Framework for Recommendation in Museums: From Preference Elicitation to Group's Visits
No full textRecommendation systems based on collaborative filtering methods can be exploited in the context of providing personalized artworks tours within a museum. However, in order to be effectively used, several problems have to be addressed: user preferences are not expressed as rating, items to be suggested are located in a physical space, and users may be in a group. In this work, we present a general framework that, by using the Matrix Factorization (MF) approach and a graph representation of a museum, addresses the problem of generating and then recommending an artworks sequence for a group of visitors within a museum. To reach a high-quality initial personalization, the recommendation system uses a simple, but efficient, elicitation method that is inspired by the MF approach. Moreover, the proposed approach considers the individual or the aggregated artworks’ ratings to build up a solution that takes into account the physical location of the artworks
Going technocratic? Diluting governing responsibility in electorally turbulent times
No full textTechnocracy has recently triggered growing scholarly interest, especially as an alternative form of ruling to both party government and populism. In the context of weakened parties-citizens links and increasing external constraints faced by Western European ruling parties, technocratic appointments might help deal with the responsibility-responsiveness dilemma highlighted by Peter Mair. However, research on the explanatory factors of technocratic appointments is still underdeveloped. This article argues that the recourse to technocracy is fuelled by electoral volatility. In contexts of high electoral turbulence - and even more when parties frequently enter or exit the party system - ruling parties turn to technocratic appointments to dilute responsibility. This expectation is tested through an original longitudinal multilevel dataset including 655 cabinets and 373 elections in 20 Western European countries from 1945 to 2021. The findings of this article contribute to the current debate on technocracy and shed new light on the general understanding behind political representation
L'arte di fare (e disfare) i governi. Da De Gasperi a Renzi, 70 anni di politica italiana By Luigi Curini and Luca Pinto. Milano: Egea, 2017. 227p. 28
No full textDigital Innovation in Healthcare: A Device with A Method for Monitoring, Managing and Preventing the Risk of Chronic Polypathological Patients
No full textNew digital technologies can have a huge impact on the traditional healthcare sector, both from a clinical and economic perspective. Doctors and health specialists will increasingly need technology to improve the services they provide to their patients. Here a novel patented device for automatic processing of clinical data of chronic poly-pathological patients is presented. The invention consists of a reconfigurable equipment that allows the assessment of clinical risk severity indexes that can be customized for polypathological patients and which acts both as a decision support system for specialist doctors in the diagnosis and treatment phases, and as a monitoring system in the clinical environment
A qualitative approach for the Health Technology Assessment of IT supported Type 2 Diabetes management tools
No full textThe health technology assessment is fundamental in the acquisition of novel technologies and it is an important tool for the decision makers. With the development of novel emerging mobile-health apps, devices, software and In-formation and Communication Technologies (ICT), the evaluation over a wide range of available products is a critical issue. Here we propose a questionnaire-based approach to assess ICT tools able to facilitate the lives of people with Type 2 Diabetes Mellitus (T2DM). We used a 5-point Likert scale as a psychometric scale to assess experts' opinions regarding novel tools for the T2DM self-management. Preliminary data collected through the administration of the questionnaire show the relative importance of the functionalities and features of the examined technologies, giving opportunities for future improvements
AudioMagnetoTelluric (AMT) and Geochemical data in the Campi Flegrei caldera
No full textEDI files of the AMT data and Geochemical data used in the article "Reservoir structure, hydraulic properties and fluid-related seismicity at the Campi Flegrei geothermal system inferred by audiomagnetotelluric surveying" submitted to Journal of Geophysical Research Solid Eart
The Fcp1-Wee1-Cdk1 axis affects spindle assembly checkpoint robustness and sensitivity to antimicrotubule cancer drugs
No full textTo grant faithful chromosome segregation, the spindle assembly checkpoint (SAC) delays mitosis exit until mitotic spindle assembly. An exceedingly prolonged mitosis, however, promotes cell death and by this means antimicrotubule cancer drugs (AMCDs), that impair spindle assembly, are believed to kill cancer cells. Despite malformed spindles, cancer cells can, however, slip through SAC, exit mitosis prematurely and resist killing. We show here that the Fcp1 phosphatase and Wee1, the cyclin B-dependent kinase (cdk) 1 inhibitory kinase, play a role for this slippage/resistance mechanism. During AMCD-induced prolonged mitosis, Fcp1-dependent Wee1 reactivation lowered cdk1 activity, weakening SAC-dependent mitotic arrest and leading to mitosis exit and survival. Conversely, genetic or chemical Wee1 inhibition strengthened the SAC, further extended mitosis, reduced antiapoptotic protein Mcl-1 to a minimum and potentiated killing in several, AMCD-treated cancer cell lines and primary human adult lymphoblastic leukemia cells. Thus, the Fcp1-Wee1-Cdk1 (FWC) axis affects SAC robustness and AMCDs sensitivity
Analisi di mutazione dei geni BRCA 1 E BRCA 2 in pazienti con carcinoma ereditario della mammella
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