1,720,960 research outputs found
Lithium treatment in children and adolescents with anorexia nervosa: clinical use, side effects and tolerability
No full textPurpose. Current guidelines, due to potential
toxicity and lack of clinical evidence, do not recommend
the use of lithium in the treatment of Anorexia
Nervosa (AN). Scarce evidence is available on the use,
side effects, and tolerability of this drug in children and
adolescents with AN, a population characterized by
specific clinical, metabolic, and hydro-electrolytic balance
features. Here we report a case series of children
and adolescents hospitalized for AN and treated with
lithium. Methods. Case series reporting the use of
lithium in 7 female young patients with AN. Reasons
for introduction, dosages, formulation, plasma
levels,
adverse drug reactions (ADR) and modifications
of electrocardiogram
(EKG) and plasma levels of glucose, cholesterol,
creatinine, urea, sodium, and thyroid-stimulating
hormone (TSH) were assessed. Results.
Reasons
for the introduction of lithium included unstable mood,
insufficient compliance with nutritional
programs, and
psychomotor agitation. In all of the patients an improvement
on target symptoms was observed. Lithium
was started at 171.4 (+/-56.7) mg/day, up to 600.0 (+/-
173.2) mg/day. The most frequent scheme was three
times daily. The mean plasmatic concentration was
0.6 (+/-0.3) mmol/L at one month. One patient
experienced
polyuria, polydipsia and dry mouth, and another
showed increased creatinine kinase. No major
modifications of EKG, glucose, cholesterol, creatinine,
urea, sodium emerged. Conclusions. In this sample of
children and adolescents hospitalized for AN, lithium
was administered to improve psychiatric symptoms
impairing compliance. All the patients experienced an
improvement on these symptoms after being administered
lithium. ADR were reported in 2 cases. These
data should be investigated in wider populations and
controlled studies
SUNCT/SUNA in Pediatric Age: A Review of Pathophysiology and Therapeutic Options
Full text linkThe International Classification of Headache Disorders, 3rd edition (ICHD3) defines Shortlasting
Unilateral Neuralgiform Headache Attacks (SUNHA) as attacks of moderate or severe, strictly
unilateral head pain lasting from seconds to minutes, occurring at least once a day and usually
associated with prominent lacrimation and redness of the ipsilateral eye. Two subtypes of SUNHA
are identified: Short-lasting Unilateral Neuralgiform headache attacks with Conjunctival injection
and Tearing (SUNCT) and Short-lasting Unilateral Neuralgiform headache attacks with cranial
Autonomic symptoms (SUNA). These pathologies are infrequent in children and difficult to diagnose.
The authors reviewed the existing literature on SUNCT and SUNA, especially in the developmental
age, which describes the pathophysiology in detail and focuses on the therapeutic options available
to date. SUNHA-type headaches must be considered on the one hand, for the possibility of the onset
of forms secondary to underlying pathologies even of a neoplastic nature, and on the other hand, for
the negative impact they can have on an individual’s quality of life, particularly in young patients.
Until now, published cases suggest that no chronic variants occur in childhood and adolescents. In
light of this evidence, the authors offer a review that may serve as a source to be drawn upon in the
implementation of suitable treatments in children and adolescents suffering from these headaches,
focusing on therapies that are non-invasive and as risk-free as possible for pediatric patients
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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