1,720,991 research outputs found
DS_10.1177_0363546518759674 – Supplemental material for Nonsurgical Treatments of Patellar Tendinopathy: Multiple Injections of Platelet-Rich Plasma Are a Suitable Option: A Systematic Review and Meta-analysis
No full textSupplemental material, DS_10.1177_0363546518759674 for Nonsurgical Treatments of Patellar Tendinopathy: Multiple Injections of Platelet-Rich Plasma Are a Suitable Option: A Systematic Review and Meta-analysis by Luca Andriolo, Sante Alessandro Altamura, Davide Reale, Christian Candrian, Stefano Zaffagnini, and Giuseppe Filardo in The American Journal of Sports Medicine</p
sj-pdf-1-car-10.1177_19476035231224951 – Supplemental material for Knee Cartilage Injuries in Football Players: Clinical Outcomes and Return to Sport After Surgical Treatment: A Systematic Review of the Literature
No full textSupplemental material, sj-pdf-1-car-10.1177_19476035231224951 for Knee Cartilage Injuries in Football Players: Clinical Outcomes and Return to Sport After Surgical Treatment: A Systematic Review of the Literature by Luca Andriolo, Theodorakys Marín Fermín, Giulia Marcella Maryse Chiari Gaggia, Andreas Serner, Elizaveta Kon, Emmanuel Papakostas, Andrew Massey, Peter Verdonk and Giuseppe Filardo in CARTILAGE</p
Long-term Results of Matrix-assisted Autologous Chondrocyte Transplantation Combined With Autologous Bone Grafting for the Treatment of Juvenile Osteochondritis Dissecans
No full textBackground: Osteochondritis dissecans is a pathology affecting
young patients that involves the entire osteochondral unit. In the
case of unfixable fragments, regenerative cartilage treatments are
a viable solution, but little is known about the use of these
procedures for the treatment of juvenile osteochondritis dissecans
(JOCD). The aim of this study was to evaluate the long-term
results offered by matrix-assisted autologous chondrocyte
transplantation combined with autologous bone grafting for the
treatment of JOCD.
Methods: Nineteen patients have been enrolled. The mean age at
the time of treatment was 16.8 ± 1.5 years, with a mean body
mass index of 22.9 ±2.7. The average size of the defects was
2.8 ±1.2 cm2. All patients were evaluated prospectively before
surgery and at 12, 24, 60, and at a final follow-up of 120 months
with International Knee Documentation Committee scores, EuroQol-
Visual Analogue Scale, and the Tegner Score.
Results: A statistically significant improvement in all clinical
scores was observed from baseline evaluation to 120 months of
final follow-up. In particular, the International Knee Documentation
Committee subjective score improved from the preoperative
evaluation of 38.7± 17.3 to 74.0 ± 21.8 at 12 months
(P< 0.0005), with scores remaining stable for up to 120 months
(83.8 ±20.7), with all follow-ups showing a statistically significant
improvement compared with the basal value
(P< 0.0005). Three patients failed at 12 months, for a failure rate
of 16% at 10 years of follow-up. Lesions >3.5 cm2 obtained
worse subjective results. In addition, lesion size and female sex
were significantly associated with failures.
Conclusions: The matrix-assisted autologous chondrocyte transplantation
technique with autologous bone grafting is a valid
treatment option for JOCD in case of unfixable fragments. The
clinical improvement obtained is significant and stable, with
good results maintained for up to 10 years of follow-up and an
overall low failure rate. Lesion size and sex could influence the
clinical outcome and should be considered in the treatment
choice.
Level of Evidence: Level IV—case series
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Cartilage repair: Scaffolding
No full textRegenerative scaffold-based procedures have emerged in the last years as a potential therapeutic option for the treatment of chondral and osteochondral lesions. The rationale of using a scaffold is to have a temporary 3D structure of biodegradable polymers for the growth of living cells. The ideal scaffold should reproduce biological and structural properties of the native tissue as close as possible, in order to allow cell infiltration, attachment, proliferation, and differentiation. Other important properties include biocompatibility and biodegradability at suitable time intervals, to support the initial tissue formation and then to be gradually replaced by the regenerating tissue. The use of scaffolds has been introduced into clinical practice to improve the results obtainable with the first-generation cell-based approach, autologous chondrocyte implantation (ACI), by overcoming its drawbacks and simplifying the procedure. ACI techniques were combined with scaffolds, developing matrix-assisted autologous chondrocyte transplantation (MACT). Cells were harvested and cultured in vitro and then seeded on the three-dimensional biomaterial, which favored the redifferentiation processes, better protection, more homogeneous distribution, and easier handling for surgical implantation. Many scaffolds have reached clinical practice, and studies are now being published with good mid- and long-term results, but showing also some limits. Whereas traumatic focal lesions of the femoral condyles were shown to have more chance of benefit from this treatment, other indications have more controversial results, with lower or even poor clinical outcome. Moreover, this approach suffers from a two-step operation, technical difficulties and regulatory restrictions for cell manipulation, and high costs. Thus, after a decade focused on expanding and improving MACT techniques, in more recent years, both researchers and clinicians have been looking for different solutions to regenerate the articular surface
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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