1,720,983 research outputs found
Characteristics of Patients with Coronary Heart Disease at Haji Adam Malik General Hospital in 2023–2024
No full textBackground: Coronary Heart Disease (CHD) remains a major cause of global
morbidity and mortality. This study aims to describe the characteristics of CHD
patients at Haji Adam Malik Hospital Medan based on individual factors and medical
history. Objective: This study aims to describe the characteristics of patients with
coronary heart disease at Haji Adam Malik General Hospital, Medan, during 2023–
2024. Methods: This research utilized a descriptive approach, using data from the
medical records of CHD patients treated at Haji Adam Malik Hospital Medan during
the 2023–2024 period. The sample includes 1,171 patients in the study. Data collection
was conducted through the Medical Records Installation and descriptively analyzed to
determine the frequency distribution and percentage of each variable. Results: Out of
1,171 CHD patients, the age distribution tends to be concentrated in the middle-aged
to elderly group. The groups with the highest frequency are in between 45-64 years old,
accounting for 709 individuals (60,5%). The gender distribution reveals a significant
dominance of males with 1,048 patients (89.5%), whereas females accounts for 123
cases (10.5%). In terms of diagnosis, CCS represents the majority of cases, accounting
for 55.42%. Prominent risk factors observed are a history of Hypertension (77.3%),
Smoking (67.5%), and Hypercholesterolemia (53.1%). A history of Diabetes Mellitus
is found in 44% of patients, whereas a family history of CHD is only found in 8.4% of
patient. Conclusion: The characteristics of CHD patients at Haji Adam Malik Hospital
ini 2023-2024 was largely composed of males, primarily within the middle-aged to
elderly range. This finding affirms that modifiable risk factors (hypertension, smoking,
and hypercholesterolemia) are the largest contributors to the pathogenesis of CHD
within this study’s population.96 PagesSkripsi Sarjan
The Associationn Between Body Mass Index and Blood Pressure at Students in Faculty of Medicine The University of Sumatera Utara
No full textBackground. In 2018, the prevalence of obesity increased from 11.7% (2010) to 15.4%. (2015). Obesity itself is a risk factor for someone to suffer from hypertension. According to data from 2018, the prevalence of hypertension in the age group of 18-24 years was 13.2%. Unhealthy lifestyles, consumption of high-fat and high-sugar foods, and lack of exercise are factors that increase the likelihood of someone becoming obese. If this is allowed to continue, it can increase the risk of someone developing cardiovascular diseases, one of which is hypertension. Objective. Analyzing the relationship between Body Mass Index and blood pressure in students of the Faculty of Medicine, Universitas Sumatera Utara. Method. This research uses an analytical approach with a cross-sectional research design and a sample of students from the Faculty of Medicine at the Universitas Sumatera Utara, selected through stratified random sampling. Data collection tools include digital body scales, microtoise, stethoscope, and sphygmomanometer. Result. Statistical analysis of 88 respondents shows that there is a significant relationship between Body Mass Index and blood pressure (p < 0.05). Correlation strength analysis indicates that Body Mass Index and blood pressure have a moderate correlation strength (Coef = 0.41-0.70). Conclusion. The higher a person's body mass index, the higher their blood pressure will be. The findings of this study emphasize the importance of maintaining an individual's body mass index at an ideal level to prevent hypertension among students of the Faculty of Medicine at the Universitas Sumatera Utara.80 PagesSkripsi Sarjan
Karakteristik Demografi Penderita Gagal Jantung di Asia: Telaah Sistematis
No full textLatar belakang. Gagal jantung adalah pandemi global yang mempengaruhi setidaknya 26 juta
orang di seluruh dunia dan prevalensinya terus meningkat. Gagal jantung juga merupakan
masalah kesehatan penting di Asia, dan prevalensinya tampaknya lebih tinggi dibandingkan
dengan negara-negara Barat, berkisar antara 1,3 % sampai 6,7 %. Saat ini di Tiongkok ada 4,2
juta orang dengan gagal jantung, dengan perkiraan prevalensi 1,3 %. Di Jepang sekitar 1 juta
orang memiliki kondisi tersebut, menyumbang 1% dari populasi. Di India perkiraannya berkisar
antara 1,3 dan 4,6 juta, yang diterjemahkan menjadi prevalensi 0,12–0,44 %, meskipun ini
mungkin diremehkan. Di Asia Tenggara, 9 juta orang memiliki gagal jantung; dengan prevalensi
6,7 % di Malaysia dan 4,5 % di Singapura. Tujuan. Studi telaah sistematis karakteristik
demografi, dan gambaran terapi pasien penderita gagal jantung di Asia. Metode. Pencarian
literatur dilakukan pada 1 database literatur yaitu PubMed hingga 20 Agustus 2021 dengan
luaran studi Karakteristik Demografi dan gambaran terapi pada pasien penderita gagal jantung
di Asia sesuai dengan tahapan PRISMA menggunakan kata kunci yang relevan serta telaah
kualitas jurnal berdasarkan NOS.Hasil. Total 12 studi literatur karakteristik penderita Gagal
Jantung di Asia dengan Dominan laki laki berusia 60 tahun dan 10 literatur menyatakan Riwayat
hipertensi dan CAD sebagai etiologi dari penderita Gagal Jantung di Asia. total 10 studi literatur
menyatakan Diuretic dan Beta-Blocker sebagai pengobatan tersering yang diberikan kepada
penderita gagal jantung di Asia. Kesimpulan. karakteristik penderita gagal jantung di Asia yaitu
laki laki berusia 60 tahunan, dengan etiologi hipertensi dan CAD. Tatalaksana penderita gagal
jantung yaitu diuretic dan beta-blocker.Background. Heart failure is a global pandemic that affect at least 26 million people worldwide
and its prevalence continues to rise. Heart failure is also an important health problem in Asia, and
its prevalence appears to be higher compared to Western countries, ranging from 1.3% to 6.7%.
There are currently 4.2 million people in China with heart failure, with an estimated prevalence of
1.3%. In japan about 1 million people have the condition, accounting for 1% of the population. In
India the estimate ranges between 1.3 and 4.6 million, which translates to a prevalence of 0.12 –
0.44%, although this may be underestimated. In Southeast Asia, 9 million people have heart
failure; with a prevalence of 6.7% in Malaysia and 4.5% in Singapore. Objective: to review
systematically the characteristics of demography and therapeutic of patients with heart failure in
Asia. Method: Literature searches were conducted in 1 literature database are Pubmed until
August 20th, 2021 with outcome study of demographic characteristics and of therapeutic images in
patients with heart failure in Asia by Preferred Reporting Items for Systematic Reviews and Meta-
Analyses stages using relevant keywords and reviewing journal quality based on Newcastle-
Ottawa Quality Assessment Scale assessment Result. Based on 12 literature, heart failure
characteristics risk of males aged 60 years and 10 literatures stated history of hypertension and
CAD as etiology. Based on 10 literatures state diuretics and beta-blockers as the most common
treatment given to people with heart failure in Asia Conclusion: Characteristics of heart failure
patients in Asia are males aged 60 years, with history of hypertension and CAD. Management of
patients with heart failure are diuretics and beta-blockers.71 HalamanSkripsi Sarjan
The Associationn Between Body Mass Index and Blood Pressure at Students in Faculty of Medicine The University of Sumatera Utara
No full textBackground. In 2018, the prevalence of obesity increased from 11.7% (2010) to 15.4%. (2015). Obesity itself is a risk factor for someone to suffer from hypertension. According to data from 2018, the prevalence of hypertension in the age group of 18-24 years was 13.2%. Unhealthy lifestyles, consumption of high-fat and high-sugar foods, and lack of exercise are factors that increase the likelihood of someone becoming obese. If this is allowed to continue, it can increase the risk of someone developing cardiovascular diseases, one of which is hypertension. Objective. Analyzing the relationship between Body Mass Index and blood pressure in students of the Faculty of Medicine, Universitas Sumatera Utara. Method. This research uses an analytical approach with a cross-sectional research design and a sample of students from the Faculty of Medicine at the Universitas Sumatera Utara, selected through stratified random sampling. Data collection tools include digital body scales, microtoise, stethoscope, and sphygmomanometer. Result. Statistical analysis of 88 respondents shows that there is a significant relationship between Body Mass Index and blood pressure (p < 0.05). Correlation strength analysis indicates that Body Mass Index and blood pressure have a moderate correlation strength (Coef = 0.41-0.70). Conclusion. The higher a person's body mass index, the higher their blood pressure will be. The findings of this study emphasize the importance of maintaining an individual's body mass index at an ideal level to prevent hypertension among students of the Faculty of Medicine at the Universitas Sumatera Utara.80 PagesSkripsi Sarjan
Gambaran Tingkat Pengetahuan Resiko Sudden Cardiac Death dan Pengaruh Aktivitas Fisik pada Masyarakat Kota Medan
Get PDFBackground Sudden cardiac death (SCD) is a sudden unexpected death due to a cardiac condition characterized by a post-mortem examination of sudden loss of consciousness within 1 hour of the onset of acute symptoms that may be accompanied by a previous history of heart disease. SCD is the leading cause of death in western countries around 15%-20% and accounts for the majority of deaths from cardiovascular disease. Most SCD is associated with exercise occurring in recreational rather than competitive environments especially among the middle-aged population. Aim. To determine the level of knowledge about Sudden Cardiac Death risk and the influence of physical activity in Medan City community. Methods. This study used a descriptive design with a cross-sectional approach by collecting respondents in the form of Medan City aged 25 – 65 years through questionnaires as research data. Results. From 179 respondents, it was found that for general knowledge, there were 140 people (78.2%) in the good category, 28 people (15.6%) in the moderate category, followed by 11 people (6.1%) in the poor category. Then in prognosis knowledge, 59 people (33.0%) were in the good category, 81 people (45.3%) were in the moderate category, and 31 people (21.8%) were in the poor category. Conclusion. The picture of the general level of knowledge of the community is good while the prognosis of knowledge is moderate.86 HalamanSkripsi Sarjan
Gambaran Tingkat Pengetahuan Resiko Sudden Cardiac Death dan Pengaruh Aktivitas Fisik pada Masyarakat Kota Medan
Get PDFBackground Sudden cardiac death (SCD) is a sudden unexpected death due to a cardiac condition characterized by a post-mortem examination of sudden loss of consciousness within 1 hour of the onset of acute symptoms that may be accompanied by a previous history of heart disease. SCD is the leading cause of death in western countries around 15%-20% and accounts for the majority of deaths from cardiovascular disease. Most SCD is associated with exercise occurring in recreational rather than competitive environments especially among the middle-aged population. Aim. To determine the level of knowledge about Sudden Cardiac Death risk and the influence of physical activity in Medan City community. Methods. This study used a descriptive design with a cross-sectional approach by collecting respondents in the form of Medan City aged 25 – 65 years through questionnaires as research data. Results. From 179 respondents, it was found that for general knowledge, there were 140 people (78.2%) in the good category, 28 people (15.6%) in the moderate category, followed by 11 people (6.1%) in the poor category. Then in prognosis knowledge, 59 people (33.0%) were in the good category, 81 people (45.3%) were in the moderate category, and 31 people (21.8%) were in the poor category. Conclusion. The picture of the general level of knowledge of the community is good while the prognosis of knowledge is moderate.86 HalamanSkripsi Sarjan
Gambaran Tingkat Pengetahuan Resiko Sudden Cardiac Death dan Pengaruh Aktivitas Fisik pada Masyarakat Kota Medan
Get PDFBackground Sudden cardiac death (SCD) is a sudden unexpected death due to a cardiac condition characterized by a post-mortem examination of sudden loss of consciousness within 1 hour of the onset of acute symptoms that may be accompanied by a previous history of heart disease. SCD is the leading cause of death in western countries around 15%-20% and accounts for the majority of deaths from cardiovascular disease. Most SCD is associated with exercise occurring in recreational rather than competitive environments especially among the middle-aged population. Aim. To determine the level of knowledge about Sudden Cardiac Death risk and the influence of physical activity in Medan City community. Methods. This study used a descriptive design with a cross-sectional approach by collecting respondents in the form of Medan City aged 25 – 65 years through questionnaires as research data. Results. From 179 respondents, it was found that for general knowledge, there were 140 people (78.2%) in the good category, 28 people (15.6%) in the moderate category, followed by 11 people (6.1%) in the poor category. Then in prognosis knowledge, 59 people (33.0%) were in the good category, 81 people (45.3%) were in the moderate category, and 31 people (21.8%) were in the poor category. Conclusion. The picture of the general level of knowledge of the community is good while the prognosis of knowledge is moderate.86 HalamanSkripsi Sarjan
“Gambaran Tingkat Kecemasan pada Penderita Gagal Jantung Kronis di RSUP Haji Adam Malik dan Rumah Sakit Universitas Sumatera Utara di Periode COVID-19
No full textLatar Belakang: Penyakit kardiovaskular merupakan penyebab kematian nomor satu di dunia. Diperkirakan 23,6 juta penduduk dunia akan meninggal karena penyakit kardiovaskular pada tahun 2030. Di Indonesia terdapat 229.696 pasien terdiagnosis gagal jantung menurut Departemen Kesehatan pada Tahun 2013. Pasien yang menderita gagal jantung untuk beberapa waktu sering disebut gagal jantung kronis. Pada studi, 28,8% masyarakat dilaporkan memiliki kecemasan sedang hingga kecemasan berat terhadap pandemi COVID-19. Tujuan: Mengetahui gambaran tingkat kecemasan pada penderita gagal jantung kronis di RSUP HAM dan RS USU di periode COVID-19. Metode: Penelitian deskriptif dengan desain cross sectional. Populasi penelitian adalah penderita gagal jantung kronis yang terdaftar di RSUP HAM dan RS USU. Penentuan sampel dengan menggunakan metode purposive sampling. Data yang digunakan adalah data sekunder dan data primer menggunakan kuesioner SAS/SRAS saat wawancara melalui telepon genggam dan dengan bantuan pihak rumah sakit untuk dibagikan. Data kemudian dianalisis menggunakan program komputer. Hasil: Tingkat kecemasan terbanyak pada pasien gagal jantung kronis di RSUP HAM dan RS USU di periode COVID-19 adalah kecemasan ringan (67%). Berdasarkan klasifikasi NYHA terbanyak Fc II (65%) mengalami kecemasan ringan (43%) dan hanya pada Fc III didapatkan tingkat kecemasan panik (1%). Berdasarkan kategori LVEF pada pasien di RSUP HAM terbanyak adalah HFpEF (35%) mengalami kecemasan ringan (26%) dan hanya pada HFrEF memiliki tingkat kecemasan panik (1%). Frekuensi usia terbanyak adalah kelompok usia 51-60 tahun (35%). Frekuensi jenis kelamin terbanyak adalah laki-laki (59%). Kesimpulan: Tingkat kecemasan pada penderita gagal jantung kronis di RSUP HAM dan RS USU yang terbanyak adalah kecemasan ringan.96 HalamanSkripsi Sarjan
Perbandingan Reperfusi Pada Pasien Imaest yang Diterapi dengan Ticagrelor dan Clopidogrel yang dinilai Secara Myocardial Blush Grade (Mbg) dan Timi Frame Count (Tfc) pada Waktu Terapi Intervensi Koroner Perkutan Primer
No full textIntroduction : Coronary Arterial Disease (CAD) is the main cause of death globally where
specifically in Indonesia, approximately 1 per 4 people could be died with mortality rate 26,4%,
this number was much higher than mortality of cancer (PERKI, 2019). Angiographically,
reperfusion in myocardial tissue assessed by TIMI frame count (TFC) and Myocardial Blush
Grade (MBG) could show the level of contrast density of myocardial tissue related to infarction
and correlated with survival after Percutaneous Coronary Intervention (PCI). Nowadays in
Indonesia, ticagrelor and clopidogrel are the only available oral direct-acting antiplatelet
therapy before PCI. Ticagrelor could be an effective alternative for patients with clopidogrel
resistance. Therefore, the aim of this study is to assess whether any reperfusion differences
between STEMI patients administered with ticagrelor or clopidogrel that evaluated using
myocardial blush grade (MBG) and TIMI Frame Count (TFC) after PPCI.
Method : We conducted a retrospective cross-sectional study with comparative analytical
study.. Sample collected consecutively. Subjects were STEMI patients who performed PCI at
RSUP H. Adam Malik Medan and RS Murni Teguh Memorial Hospital with sample collected
secondarily from medical record since October 2021until minimum sample size achieved. Data
was collected after performing clinical assessment, ECG examination, cardiac enzyme, history
of medical therapy and coronary angiography.
Result : Mean age of study population is 56 years, mostly male (93,3%), history of smoking (
73,3%), and hypertension found to be the most frequent risk factor (53,3). Median uric acid
level is 26 mg/ ml, median creatinine level is 0,998 mg/ml, median troponin I is 1,75 ng/ml.
Median length of stay is 4 days. Median myocardial blush grade (MBG) is 2. Median TIMI
Frame count is 22. Majority of patients was KILLIP I (65%), on ACE-I therapy (46,7%), on
statin 40 mg (63,3%) and ticagrelor (55%). Based on time to wire, most PCI performed > 90
minutes, (76,7%) and the most frequent myocardial infarction area is anterior (53,5%) Based
on bivariate analysis, there was statistically significant differences between subjects
administered clopidogrel and ticagrelor based on history of smoking (=0,026), uric acid level
(p=0,026), myocardial blush grade (p=0,007), TFC (value p<0,001), KILLIP class (value
p=0,010), and ACE-inhibitor (p=0,017)Latar Belakang : Penyakit Jantung Koroner (PJK) merupakan penyebab utama dari seluruh
kematian dimana setiap satu diantara empat orang meninggal dunia di Indonesia akibat PJK
dengan mortalitasnya mencapai 26.4%, angka ini mengalahkan angka kematian oleh kanker
yang berkisar di 6% (Perki, 2019). Reperfusi tingkat jaringan secara angiografik dengan
parameter seperti TIMI frame count (TFC) dan myocardial blush grade (MBG) dapat
memberikan gambaran fungsi mikrovaskular pada area miokard yang terkait. Saat ini di
Indonesia, pengobatan dengan obat anti-platelet direct-acting sebelum IKP di Indonesia hanya
tersedia tigacrelor dan clopidogrel. Ticagrelor dapat menjadi terapi alternatif yang efektif untuk
bagi pasien dengan resistensi clopidogrel. Oleh karena itu, studi ini dilakukan untuk menilai
apakah terdapat perbedaan reperfusi pada pasien IMAEST yang diterapi dengan ticagrelor dan
clopidogrel yang dinilai dengan MBG dan TFC setelah terapi intervensi koroner perkutan
primer.
Metode : Penelitian ini merupakan suatu studi desain potong lintang (cross sectional)
retrospektif dengan analisis komparatif numerik, dimana pengambilan sampel dilakukan
dengan cara consecutive sampling. Subjek penelitian ini adalah pasien IMAEST yang
menjalani terapi IKP primer di RSUP H. Adam Malik Medan dan RS Murni Teguh Memorial
Hospital dengan pengambilan data sekunder dari Rekam Medis dilakukan mulai dari periode
Oktober 2021 hingga jumlah sampel terpenuhi. Data sekunder diambil melalui pemeriksaan
EKG, klinis, enzim jantung, terapi, serta angiografi koroner.
Hasil : Rerata usia subjek penelitian adalah 56 tahun, mayoritas laki-laki (93,3%), riwayat
merokok (73,3%), dan Hipertensi merupakan faktor risiko yang paling banyak ditemui
(53,3%). Median kadar ureum yaitu 26 mg/ ml, median kadar kreatinin 0,998 mg/ml, median
troponin I yaitu 1,75 ng/ml. Berdasearkan lama rawatan, median lama rawatan pasien yaitu
selama 4 hari. Median myocardial blush grade (MBG) yaitu 2. Median TFC subjek penelitian
yaitu 22. Berdasarkan KILLIP, mayoritas subjek penelitian Killip I sebanyak 39 orang (65%).
Sebagian besar pasien mendapatkan terapi ACE-I (46,7%), statin 40 mg (63,3%) dan ticagrelor
(55%). Berdasarkan waktu door to wire, tindakan IKP terbanyak >90 menit (76,7%) dan lokasi
infark paling banyak ditemukan pada bagian anterior (53,3%). Berdasarkan analisis bivariat,
terdapat perbedaan yang signifikan secara statistik pasien yang merokok (nilai p=0,026), kadar
ureum (nilai p=0,027), myocardial blush grade (nilai p=0,007), TFC (nilai p<0,001), KILLIP
(nilai p=0,010), dan ACE-inhibitor (nilai p=0,017) dengan pemberian terapi antara clopidogrel
dan ticagrelor.
Kesimpulan : Terdapat perbedaan yang signifikan secara statistik pada myocardial blush grade
(MBG) dengan pemberian terapi antara clopidogrel dan ticagrelor serta erdapat perbedaan yang
signifikan secara statistik pada TFC dengan pemberian terapi antara clopidogrel dan ticagrelor.88 HalamanTesis Magiste
Hubungan antara Tingginya Nilai Systemic Immune Inflammatory Index (SII) dengan Tingkat Keparahan Lesi Koroner pada Pasien Chronic Coronary Syndrome (CCS) yang Menjalani Angiografi Koroner di RSUP Haji Adam Malik Medan
Get PDFLatar Belakang: Diketahui bahwa proses inflamasi berperan penting dalam
pembentukan dan perkembangan aterosklerosis sebagai proses patologis penyakit
jantung koroner. Indeks hematologi sederhana, seperti rasio neutrofil-limfosit (NLR),
rasio monosit-limfosit (MLR), dan rasio trombosit-limfosit (PLR) telah terbukti
menjadi penanda aterosklerosis, dan berhubungan dengan prevalensi penyakit jantung
koroner dan luaran kardiovaskular yang buruk. Systemic immune inflammatory index
(SII) adalah indikator inflamasi yang relatif baru yang diperoleh dari kombinasi
jumlah neutrofil, trombosit, dan limfosit. Hubungan nilai SII sebagai prediktor
keparahan lesi koroner pada pasien CCS masih belum banyak diketahui. Tujuan
penelitian ini adalah untuk mengetahui korelasi antara nilai SII dengan keparahan lesi
koroner pada pasien CCS melalui skor SYNTAX yang menjalani angiografi koroner.
Metode: Studi ini adalah studi observasional deskriptif dengan metode retrospektif
untuk menganalisis korelasi antara nilai SII dengan keparahan lesi koroner pada
pasien CCS melalui skor SYNTAX yang diambil mulai dari Juni hingga Agustus
2024. Kriteria keparahan lesi koroner dikelompokkan berdasarkan skor SYNTAX.
Dilakukan uji mean, uji multivariat logistik regresi, korelasi Spearman dan kurva
ROC serta penilaian sensitivitas dan spesifisitas pada kelompok skor SYNTAX ringan,
sedang dan berat. Nilai p <0,05 dianggap bermakna secara statistik.
Hasil: Subjek penelitian berjumlah 115 sampel dengan rata-rata usia 59,41 ± 9,45,
dengan jumlah sampel laki laki sebanyak 78 sampel (67,8%). Didapati nilai SII
memiliki korelasi yang kuat dengan skor SYNTAX, yaitu pada skor SYNTAX ringan
365,7 (183,45 - 853,91), skor SYNTAX sedang 695,52 (534,83 - 1838,57), dan skor
SYNTAX berat 1026,7 (413,57 - 3813,83; p value <0,001)
Kesimpulan: Terdapat hubungan antara nilai SII dengan keparahan lesi koroner yang
dihitung dengan skor SYNTAX, dengan nilai SII lebih tinggi pada skor SYNTAX
berat dibandingkan dengan skor SYNTAX sedang dan ringan.61 PagesTesis Magiste
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