1,935 research outputs found

    Observation of hc radiative decay hc › ??' and evidence for hc › ??

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    Kolcu, Onur Buğra (Arel Author) --- Makale 69 yazarlıdır.A search for radiative decays of the P-wave spin singlet charmonium resonance hc is performed based on 4.48 × 108 ? events collected with the BESIII detector operating at the BEPCII storage ring. Events of the reaction channels hc › ??' and ?? are observed with a statistical significance of 8.4? and 4.0?, respectively, for the first time. The branching fractions of hc › ??' and hc › ?? are measured to be B(hc › ??' ) = (1.52±0.27±0.29)×10-3 and B(hc › ??) = (4.7±1.5±1.4)×10-4 , respectively, where the first errors are statistical and the second are systematic uncertainties

    SCCS SCIENTIFIC ADVICE ON HC Yellow No. 16 (Colipa No. B123) (CAS No. 1184721-10-5) - Submission IISCCS/1670/24 - Preliminary Opinion

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    International audienceSCCS SCIENTIFIC ADVICE ON HC Yellow No. 16 (Colipa No. B123) (CAS No. 1184721-10-5) - Submission IISCCS/1670/24 - Preliminary OpinionPreliminary Opinion open for comments - Deadline for comments: 27 September 2024U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads, J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. Wijnhoven, E. Benfentati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro, W. Uter, N. von GoetzThe SCCS adopted this document by written procedure on 31 July 2024 (30 pages)Publication date : 1st August 2024https://health.ec.europa.eu/publications/sccs-scientific-advice-hc-yellow-no-16-colipa-no-b123-cas-no-1184721-10-5-submission-ii_enhttps://health.ec.europa.eu/document/download/73062780-ac23-433b-8c45-1bce0ed935b2_en?filename=sccs_o_292.pdfDetailsPublication date : 1 August 2024Author : Scientific Committee on Consumer Safety (SCCS)DescriptionSCCS members: U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads (Chairperson), J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. WijnhovenSCCS external experts: E. Benfenati, N. Cabaton, E. Corsini, A. Koutsodimou (Rapporteur), H. Louro, W. Uter, N. von Goetz Contact: [email protected] request from: European CommissionSCCS Number: SCCS/1670/24Adopted on: 31July 2024Conclusion of the opinion:(1) In light of the data provided, does the SCCS consider HC Yellow 16 safe, when used as an ingredient at 1 % in oxidative hair dye and at 1.5 % in non-oxidative hair dye formulations?In the light of the data provided, SCCS considers that the use of HC Yellow No. 16 (B123) as an ingredient at 1% in oxidative hair dye formulations and at 1.5% in non-oxidative hair dye formulations is safe, considering the specifications of the new commercial batches as described in the submission II file.(2) Does the SCCS have any further scientific concerns with regard to the use of HC Yellow 16 in cosmetic products?/Keywords:SCCS, scientific advice, hair dye, HC Yellow No. 16, B123, Submission II, CAS 1184721-10-5, Regulation 1223/2009Opinion to be cited as:SCCS (Scientific Committee on Consumer Safety), scientific advice on hair dye HC Yellow No. 16 (Colipa No B123) (CAS No. 1184721-10-5) – Submission II, preliminary version of 31 July 2024, SCCS/1670/24

    SCCS - SCIENTIFIC ADVICE ON HC Red No. 18 (Colipa No. B124) (CAS No. 1444596-49-9) - Submission II - SCCS/1673/24 - Final version

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    International audienceSCCS - SCIENTIFIC ADVICE ON HC Red No. 18 (Colipa No. B124) (CAS No. 1444596-49-9) - Submission II - SCCS/1673/24 - Final versionU. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads, J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. Wijnhoven, E. Benfentati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro, W. Uter, N. von GoetzThe SCCS adopted this document by written procedure on 22 January 2025 (39 pages)Mise en ligne : 23 Janvier 2025https://health.ec.europa.eu/publications/sccs-scientific-advice-hc-red-no-18-colipa-no-b124-cas-no-1444596-49-9-submission-ii_enhttps://health.ec.europa.eu/document/download/e921f990-7a44-4825-a15e-cd8e6a6bbc15_en?filename=sccs_o_295.pdfPublication date : 23 January 2025Author : Scientific Committee on Consumer Safety (SCCS)DescriptionSCCS members: U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads (Chairperson), J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri (Rapporteur), V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. WijnhovenSCCS external experts: E. Benfentati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro , W. Uter, N. von GoetzContact: [email protected] request from: European CommissionSCCS Number: SCCS/1673/24Adopted on: 22 January 2025Conclusion of the opinion:(1) In light of the data provided, does the SCCS consider HC Red 18 safe, when used as an ingredient at 1.5% in oxidative hair dye and at 0.5% in non-oxidative hair dye formulations?In light of the data provided, the SCCS considers HC Red 18 safe when used as an ingredient at 1.5% in oxidative hair dye and at 0.5% in non-oxidative hair dye formulations.(2) Does the SCCS have any further scientific concerns with regard to the use of HC Red 18 in cosmetic products?/Keywords:SCCS, scientific advice, hair dye, HC Red No. 18 (В124), CAS 1444596-49-9, submission II, Regulation 1223/2009Opinion to be cited as:SCCS (Scientific Committee on Consumer Safety), scientific advice on HC Red No. 18 (В124) (CAS 1444596-49-9) – submission II, preliminary version of 6 December 2024, final version of 22 January 2025, SCCS/1673/24

    SCCS SCIENTIFIC ADVICE ON HC Yellow No. 16 (Colipa No. B123) (CAS No. 1184721-10-5) - Submission II - SCCS/1670/24 – Final version

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    International audienceSCCS SCIENTIFIC ADVICE ON HC Yellow No. 16 (Colipa No. B123) (CAS No. 1184721-10-5) - Submission II - SCCS/1670/24 – Final versionU. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads, J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. Wijnhoven, E. Benfenati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro, W. Uter, N. von GoetzThe SCCS adopted this Opinion during the plenary meeting on 25 October 2024 (30 Pages)Mise en ligne : 25 October 2024https://health.ec.europa.eu/publications/sccs-scientific-advice-hc-yellow-no-16-colipa-no-b123-cas-no-1184721-10-5-submission-ii_enhttps://health.ec.europa.eu/document/download/73062780-ac23-433b-8c45-1bce0ed935b2_en?filename=sccs_o_292.pdfDetailsPublication date25 October 2024AuthorScientific Committee on Consumer Safety (SCCS)DescriptionSCCS members: U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads (Chairperson), J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. WijnhovenSCCS external experts: E. Benfenati, N. Cabaton, E. Corsini, A. Koutsodimou (Rapporteur), H. Louro, W. Uter, N. von Goetz Contact: [email protected] request from: European CommissionSCCS Number: SCCS/1670/24Adopted on: 25 October 2024Conclusion of the opinion:(1) In light of the data provided, does the SCCS consider HC Yellow 16 safe, when used as an ingredient at 1 % in oxidative hair dye and at 1.5 % in non-oxidative hair dye formulations?In the light of the data provided, SCCS considers that the use of HC Yellow No. 16 (B123) as an ingredient at 1% in oxidative hair dye formulations and at 1.5% in non-oxidative hair dye formulations is safe, considering the specifications of the new commercial batches as described in the submission file II (as detailed in section 3.1.4).(2) Does the SCCS have any further scientific concerns with regard to the use of HC Yellow 16 in cosmetic products?/Keywords:SCCS, scientific advice, hair dye, HC Yellow No. 16, B123, Submission II, CAS 1184721-10-5, Regulation 1223/2009Opinion to be cited as:SCCS (Scientific Committee on Consumer Safety), scientific advice on hair dye HC Yellow No. 16 (Colipa No B123) (CAS No. 1184721-10-5) – Submission II, preliminary version of 31 July 2024, final version of 25 October 2024, SCCS/1670/24

    SCCS - SCIENTIFIC ADVICE ON HC Red No. 18 (Colipa No. B124) (CAS No. 1444596-49-9) - Submission II - SCCS/1673/24 - Preliminary version

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    International audienceSCCS - SCIENTIFIC ADVICE ON HC Red No. 18 (Colipa No. B124) (CAS No. 1444596-49-9) - Submission II - SCCS/1673/24 - Preliminary versionPreliminary Opinion open for comments - Deadline for comments: 13 January 2025The SCCS adopted this document by written procedure on 6 December 2024 (39 pages)U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads, J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. Wijnhoven, E. Benfentati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro, W. Uter, N. von GoetzMise en ligne : 10 December 2024https://health.ec.europa.eu/publications/sccs-scientific-advice-hc-red-no-18-colipa-no-b124-cas-no-1444596-49-9-submission-ii_enhttps://health.ec.europa.eu/document/download/e921f990-7a44-4825-a15e-cd8e6a6bbc15_en?filename=sccs_o_295.pdfDetailsPublication date10 December 2024AuthorScientific Committee on Consumer Safety (SCCS)DescriptionSCCS members: U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads (Chairperson), J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri (Rapporteur), V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. WijnhovenSCCS external experts: E. Benfentati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro , W. Uter, N. von GoetzContact: [email protected] request from: European CommissionSCCS Number: SCCS/1673/24Adopted on: 6 December 2024Conclusion of the opinion:(1) In light of the data provided, does the SCCS consider HC Red 18 safe, when used as an ingredient at 1.5% in oxidative hair dye and at 0.5% in non-oxidative hair dye formulations?In light of the data provided, the SCCS considers HC Red 18 safe when used as an ingredient at 1.5% in oxidative hair dye and at 0.5% in non-oxidative hair dye formulations.(2) Does the SCCS have any further scientific concerns with regard to the use of HC Red 18 in cosmetic products?/Keywords:SCCS, scientific advice, hair dye, HC Red No. 18 (В124), CAS 1444596-49-9, submission II, Regulation 1223/2009Opinion to be cited as:SCCS (Scientific Committee on Consumer Safety), scientific advice on HC Red No. 18 (В124) (CAS 1444596-49-9) – submission II, preliminary version of 6 December 2024, SCCS/1673/24

    SCCS SCIENTIFIC ADVICE ON HC Yellow No. 16 (Colipa No. B123) (CAS No. 1184721-10-5) - Submission II - SCCS/1670/24 – Final version

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    International audienceSCCS SCIENTIFIC ADVICE ON HC Yellow No. 16 (Colipa No. B123) (CAS No. 1184721-10-5) - Submission II - SCCS/1670/24 – Final versionU. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads, J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. Wijnhoven, E. Benfenati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro, W. Uter, N. von GoetzThe SCCS adopted this Opinion during the plenary meeting on 25 October 2024 (30 Pages)Mise en ligne : 25 October 2024https://health.ec.europa.eu/publications/sccs-scientific-advice-hc-yellow-no-16-colipa-no-b123-cas-no-1184721-10-5-submission-ii_enhttps://health.ec.europa.eu/document/download/73062780-ac23-433b-8c45-1bce0ed935b2_en?filename=sccs_o_292.pdfDetailsPublication date25 October 2024AuthorScientific Committee on Consumer Safety (SCCS)DescriptionSCCS members: U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads (Chairperson), J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. WijnhovenSCCS external experts: E. Benfenati, N. Cabaton, E. Corsini, A. Koutsodimou (Rapporteur), H. Louro, W. Uter, N. von Goetz Contact: [email protected] request from: European CommissionSCCS Number: SCCS/1670/24Adopted on: 25 October 2024Conclusion of the opinion:(1) In light of the data provided, does the SCCS consider HC Yellow 16 safe, when used as an ingredient at 1 % in oxidative hair dye and at 1.5 % in non-oxidative hair dye formulations?In the light of the data provided, SCCS considers that the use of HC Yellow No. 16 (B123) as an ingredient at 1% in oxidative hair dye formulations and at 1.5% in non-oxidative hair dye formulations is safe, considering the specifications of the new commercial batches as described in the submission file II (as detailed in section 3.1.4).(2) Does the SCCS have any further scientific concerns with regard to the use of HC Yellow 16 in cosmetic products?/Keywords:SCCS, scientific advice, hair dye, HC Yellow No. 16, B123, Submission II, CAS 1184721-10-5, Regulation 1223/2009Opinion to be cited as:SCCS (Scientific Committee on Consumer Safety), scientific advice on hair dye HC Yellow No. 16 (Colipa No B123) (CAS No. 1184721-10-5) – Submission II, preliminary version of 31 July 2024, final version of 25 October 2024, SCCS/1670/24

    SCCS - SCIENTIFIC ADVICE ON HC Red No. 18 (Colipa No. B124) (CAS No. 1444596-49-9) - Submission II - SCCS/1673/24 - Final version

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    International audienceSCCS - SCIENTIFIC ADVICE ON HC Red No. 18 (Colipa No. B124) (CAS No. 1444596-49-9) - Submission II - SCCS/1673/24 - Final versionU. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads, J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. Wijnhoven, E. Benfentati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro, W. Uter, N. von GoetzThe SCCS adopted this document by written procedure on 22 January 2025 (39 pages)Mise en ligne : 23 Janvier 2025https://health.ec.europa.eu/publications/sccs-scientific-advice-hc-red-no-18-colipa-no-b124-cas-no-1444596-49-9-submission-ii_enhttps://health.ec.europa.eu/document/download/e921f990-7a44-4825-a15e-cd8e6a6bbc15_en?filename=sccs_o_295.pdfPublication date : 23 January 2025Author : Scientific Committee on Consumer Safety (SCCS)DescriptionSCCS members: U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads (Chairperson), J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri (Rapporteur), V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. WijnhovenSCCS external experts: E. Benfentati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro , W. Uter, N. von GoetzContact: [email protected] request from: European CommissionSCCS Number: SCCS/1673/24Adopted on: 22 January 2025Conclusion of the opinion:(1) In light of the data provided, does the SCCS consider HC Red 18 safe, when used as an ingredient at 1.5% in oxidative hair dye and at 0.5% in non-oxidative hair dye formulations?In light of the data provided, the SCCS considers HC Red 18 safe when used as an ingredient at 1.5% in oxidative hair dye and at 0.5% in non-oxidative hair dye formulations.(2) Does the SCCS have any further scientific concerns with regard to the use of HC Red 18 in cosmetic products?/Keywords:SCCS, scientific advice, hair dye, HC Red No. 18 (В124), CAS 1444596-49-9, submission II, Regulation 1223/2009Opinion to be cited as:SCCS (Scientific Committee on Consumer Safety), scientific advice on HC Red No. 18 (В124) (CAS 1444596-49-9) – submission II, preliminary version of 6 December 2024, final version of 22 January 2025, SCCS/1673/24

    Scientific advice on HC Blue 18 (Colipa No. B122) - Submission II

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    International audienceScientific advice on HC Blue 18 (Colipa No. B122) - Submission IIU. Bernauer, L. Bodin, Q. Chaudhry, .J. Coenraads, M. Dusinska, J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. Wijnhoven, E. Benfentati, N. Cabaton, E. Corsini, A. Koutsodimou, H. Louro, W. Uter, N. von GoetzThe SCCS adopted this document by written procedure on 27 April 2023 (24 Pages)Mise en ligne : 29th July 2024Ed. Publications Office of the European Union, Luxembourg, LuxembourgISSN 1831-4767 ISBN 978-92-68-19385-3doi:10.2875/938392Catalog Number : EW-AQ-24-003-EN-Nhttps://op.europa.eu/en/publication-detail/-/publication/90cbf7dc-4e19-11ef-acbc-01aa75ed71a1/language-en/format-PDF/source-33715512

    Financial analysis and evaluation of company HC Betons Ltd

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    Diplomdarba nosaukums: Uzņēmuma SIA HC Betons finanšu analīze un novērtējums Diplomdarba mērķis ir uz finanšu analīzes pamata izvērtēt uzņēmuma SIA HC Betons esošo finansiālo situāciju un izstrādāt priekšlikumus finansiālā stāvokļa uzlabošanai. Teorētiskajā daļā apskatīti finanšu analīzes teorētiskie aspekti. Praktiskajā daļā autore veica uzņēmuma SIA HC Betons finanšu analīzi par 2009., 2010., un 2011.gadu. Analītiskajā daļā autore salīdzina rādītājus ar konkurējošo uzņēmumu SIA Cemex. Autore secinājusi, ka uzņēmumam ir finansiālas grūtības, bet pēc autores domām, uzņēmums tuvāko gadu laikā nebankrotēs. Diplomdarba apjoms ir 78 lapaspuses, tas sastāv no 3 daļām, 12 tabulām, 5 attēliem un 12 pielikumiem. Atslēgvārdi: analīze, likviditāte, bankrots, koeficienti.Diploma thesis: Financial Analysis and Evaluation of Company HC Betons Ltd. The aim of the diploma paper is to evaluate company’s HC Betons Ltd current financial situation based on financial analysis and make suggestions for improvement of the financial position. Theoretical aspects of financial analysis are discussed in the theoretical part of the paper. In the practical part author has performed company’s HC Betons Ltd financial analysis of the years 2009, 2010 and 2011. In the analytical part author compares ratios of a competing company Cemex Ltd. The author concludes that the company is in financial difficulties, but according to the author’s thoughts, the company will not bankrupt in the coming years. The volume of the diploma paper is 78 pages; it consists of 3 parts, 12 tables, 5 images and 12 appendices. Keywords: analysis, liquidity, bankruptcy, ratios

    Metabolic profiling and population screening of analgesic usage in nuclear magnetic resonance spectroscopy-based large-scale epidemiologic studies

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    The application of a 1H nuclear magnetic resonance (NMR) spectroscopy-based screening method for determining the use of two widely available analgesics (acetaminophen and ibuprofen) in epidemiologic studies has been investigated. We used samples and data from the cross-sectional INTERMAP Study involving participants from Japan (n = 1145), China (n = 839), U.K. (n = 501), and the U.S. (n = 2195). An orthogonal projection to latent structures discriminant analysis (OPLS-DA) algorithm with an incorporated Monte Carlo resampling function was applied to the NMR data set to determine which spectra contained analgesic metabolites. OPLS-DA preprocessing parameters (normalization, bin width, scaling, and input parameters) were assessed systematically to identify an optimal acetaminophen prediction model. Subsets of INTERMAP spectra were examined to verify and validate the presence/absence of acetaminophen/ibuprofen based on known chemical shift and coupling patterns. The optimized and validated acetaminophen model correctly predicted 98.2%, and the ibuprofen model correctly predicted 99.0% of the urine specimens containing these drug metabolites. The acetaminophen and ibuprofen models were subsequently used to predict the presence/absence of these drug metabolites for the remaining INTERMAP specimens. The acetaminophen model identified 415 out of 8436 spectra as containing acetaminophen metabolite signals while the ibuprofen model identified 245 out of 8604 spectra as containing ibuprofen metabolite signals from the global data set after excluding samples used to construct the prediction models. The NMR-based metabolic screening strategy provides a new objective approach for evaluation of self-reported medication data and is extendable to other aspects of population xenometabolome profiling
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