1,721,021 research outputs found

    Indications and Timing for Intestinal/Multivisceral Transplantation

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    The progress in intestinal rehabilitation therapy has modified the strategy of treatment of CIF, moving from a straight referral for ITx of any patients with a potential risk of death on HPN to the early referral of patients to intestinal rehabilitation centers with expertise in both medical and surgical treatment for CIF, in order to maximize the opportunity of weaning off HPN, to prevent HPN-failure, and to ensure timely ITx when this is needed (19). Recent data indicate that only liver failure due to IFALD and invasive intra-abdominal desmoids are the criteria for a straight referral for ITx. CVC-related thrombosis of ≥ 2 central veins could be also considered for a life-saving ITx, in appropriately selected patients. For patients having none of the above criteria, ITx might have a potential rehabilitative role but a careful decision must be taken on a case-by-case basis for adequately informed patients

    Short Bowel Syndrome (SBS): Classification, Underlying Causes, and Global Footprint

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    An appropriate patient description is mandatory in clinical practice and as criteria for patient inclusion in research protocols. The classification of adult patients with an SBS is based on anatomical, evolutional, pathophysiological, and clinical categories and could be considered as the “SBS-ID” to report patient characteristics in clinical practice and in research studies

    TAG-19-09-246_Pape_et_al_revised_supplementary_file_final – Supplemental material for Teduglutide for the treatment of adults with intestinal failure associated with short bowel syndrome: pooled safety data from four clinical trials

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    Supplemental material, TAG-19-09-246_Pape_et_al_revised_supplementary_file_final for Teduglutide for the treatment of adults with intestinal failure associated with short bowel syndrome: pooled safety data from four clinical trials by Ulrich-Frank Pape, Kishore R. Iyer, Palle B. Jeppesen, Marek Kunecki, Loris Pironi, Stéphane M. Schneider, Douglas L. Seidner, Hak-Myung Lee and John Caminis in Therapeutic Advances in Gastroenterology</p

    Miscele nutrizionali (emulsioni) premiscelate ("Standard")

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    La presente invenzione si riferisce ad una miscela nutrizionale per uso parenterale comprendente: ione sodio ad una concentrazione compresa tra 5 75-100 mmol/L di miscela; ione cloro ad una concentrazione compresa tra 75-100 mmol/L di miscela; ione potassio ad una concentrazione compresa tra 20-30 mmol/L di miscela ed uno o più macronutrienti scelti nel gruppo comprendente lipidi, amminoacidi e zuccheri

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Monitorin patients on home parenteral nutrition

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    Monitoring of patients on home parenteral nutrition (HPN) is essential for evaluation of treatment effect and management of the complications associated with this treatment. Monitoring is most often carried out at the discharging hospital with access to the specialised nutrition team. Monitoring can also be performed by a home care agency involving the hospital or the general practitioner. Intervals between visits vary, being on average 3 months. The unstable patient may need more attention. Assignment of responsibility for monitoring is probably very important for the quality of the process. A previous questionnaire-based study indicated that in general responsibility is assigned to a specific person most often associated with the specialised team in hospital. Biochemistry, anthropometry should be measured at all visits, trace elements, vitamins and bone mineral density only occasionally, yearly intervals are recommended. Official guidelines for monitoring are not available and prospective studies on the impact of different monitoring regimens on outcome including the quality of life of HPN patients are warranted

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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