1,720,979 research outputs found
Quantitative clinical anatomy of the human cornea in vivo - A morphometric study by ultrasonic pachymetry and computer-assisted topographic videokeratoscopy
No full textThe cornea is the most important refractive element in the human ocular system, providing approximately two thirds of the eye's refractive power in the nonaccommodative state. The methods of description and analysis of the corneal anatomy in vivo continue to be refined thanks to the increased interest aroused by the advent of corneal refractive surgery, which aims to modify the dioptric power of the ocular system by altering the thickness and the radius of curvature of the cornea. In the present study we report quantitative morphometric data of corneal thickness and the radius of curvature of the anterior surface of the cornea obtained in vivo from normal human subjects using ultrasonic pachymetry and computer-assisted topographic videokeratoscopy. We found a highly significant statistical correlation in the distribution of corneal thickness and the radius of curvature of the anterior surface of the cornea along the principal corneal meridians (horizontal and vertical meridians) and within three different concentric zones of the cornea, 2, 4 and 6 mm, respectively, from the geometric center along the principal meridians. Correlation was also found for the same morphometric parameters between the right and the left eye. By contrast, no correlation was found between corneal thickness and the radius of curvature of the anterior surface of the cornea. These findings suggest that the adult human cornea is a structure characterized by a highly ordered tridimensional architecture and symmetry and that a specific distribution of corneal thickness and the radius of curvature of the anterior corneal surface along the principal meridians may be essential for the refractive function of the human corneal diopter in vivo
Cornea plana: studio clinico ed istopatologico
No full textSi esegue uno studio clinico ed istopatologico su cornea plan
Anomalia di Axenfeld in due gemelle monozigoti
No full textSi descrive un caso di due gemelle omozigoti affette da anomalia di Axenfel
Granuloma eosinofilo: caso clinico
No full textSi descrive il caso clinico di un paziente con granuloma eosinofil
Studio sull’efficacia del Diclofenac in collirio allo 0,1% nel mantenimento della midriasi farmacologica, durante chirurgia extracapsulare di cataratta
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Consolidated bioprocessing in engineered B. subtilis lab strains: γ-PGA production from biomass
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The soil bacterium B. subtilis, the model organism for Gram positive bacteria, is the best characterized member of the Bacillus genus, which includes several highly exploited industrial species. Besides industrial enzymes, Bacillus spp. can synthesize poly-γ-glutamic acid (γ-PGA), a nontoxic, biodegradable, highly anionic biopolymer made up of multiple d-/l-glutamic acid monomers joined by amide linkages between the α-NH2 and γ-COOH groups. Thanks to several valuable characteristics, γ-PGA is applied in an expanding range of biotechnological fields (Ogunleye et al., 2015), including applications as drug carrier, gene delivery and scaffold material for tissue engineering (Luo et al., 2016). γ-PGA production is also an ideal model system to develop cost-competitive feedstocks for B. subtilis aerobic fermentations.
Despite B. subtilis possessing a wide array of complex-carbohydrates degrading enzymes, direct transformation of biomass into biocommodities has not yet been reported for this microorganism.
The aim of this work was to obtain economic γ-PGA production using a waste biomass as feedstock. Rice straw is one of the most abundant biomass resources, not in competition with food, for which there are no effective valorisation strategies.
In this study, the cellulolytic capabilities of B. subtilis JH642 were maximized through self-cloning procedures, and a cheap and simple pretreatment to facilitate straw saccharification was developed.
The engineered strain grew efficiently on treated straw. Moreover, by transferring the mutations supporting γ-PGA biosynthesis (Scoffone et al., 2013) into the cellulolytic strain, direct production of γ-PGA from biomass was obtained, definitely proving the applicability of Consolidated Bioprocessing concepts to B. subtilis
Analisi degli effetti collaterali della fluoroangiografia. Descrizione di due reazioni gravi alla somministrazione endovenosa di fluoresceina.
No full textSi prendono in considerazione gli effetti collaterali della fluorangiografia, in particolare due reazioni gravi alla fluoresceina somministrata per via endovenos
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Dermatose bulleuse avec depots lin‚aires d'IgA et lesions cicatricielles oculaires graves: dermatose a IgA lineaire ou epidermolyse bulleuse acquise?
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