1,721,075 research outputs found
Vita emotiva e cognitiva degli animali nella cultura africana.
No full textRispetto ai paesi occidentali, la relazione uomo-animale in Africa si veste di particolari significati, più concreti perché legati ai bisogni fondamentali dell’uomo, ma ugualmente ricchi di importanza poiché gli animali entrano a fare parte dei riti tribali, qualificano lo status sociale e sono oggetto di razzie tra popolazioni confinanti. La Karamoja, regione poverissima dell’Uganda in cui la sopravvivenza delle persone è strettamente collegata al bestiame, è il contesto dove è stato realizzata questo studio. A 117 abitanti di questa regione (karimojong) è stato somministrato un questionario che indagava aspetti della relazione con l’animale, tra cui: l’importanza affettiva ed il ruolo sociale in famiglia e nel villaggio, l’attribuzione di capacità cognitive e comunicative, la conoscenza del mondo emotivo personale ed il confronto con quello dell’animale. Dallo studio emerge quanto sia stretto il legame che unisce la popolazione agli animali, che li considera come fonte principale di sussistenza ma al contempo degni di rispetto, poiché considerati esseri complessi, capaci di pensare (89,4% degli adulti intervistati), di comunicare (89,4%) e di provare emozioni. Ovunque ci sia un karimojong ci sono animali ma ogni singolo capo è molto più che un semplice animale da accudire, assumendo connotazioni quasi umane. I karimojong riconoscono a tutti gli animali capacità di affrontare situazioni che richiedono forme di intelligenza e di elaborazione mentali ed emotive come riconoscere situazioni di pericolo (80%), trovare la strada per il villaggio (97,9%) o fonti d’acqua (90%), provare sentimenti nei confronti dell’allevatore (81,8%). Dallo studio emerge che il rapporto tra karimojong e bestiame è sicuramente concreto e legato a necessità di sopravvivenza ma non per questo meno ricco di emotività e sentimenti. In questa terra dove uomini e animali si trovano a fronteggiare avversità devastanti, insieme riescono a trarre sostegno e giovamento gli uni dagli altri, in un equilibrio precario, sempre minacciato
Re: Pasquale Rescigno, David Lorente, Diletta Bianchini, et al. Prostate-specific Antigen Decline After 4 Weeks of Treatment with Abiraterone Acetate and Overall Survival in Patients with Metastatic Castration-resistant Prostate Cancer. Eur Urol 2016;70:724–31
No full textImmune-checkpoint inhibitors and the importance of concomitant medications: focus on antibiotics
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Pharmacokinetics, pharmacodynamics and clinical efficacy of nivolumab in the treatment of metastatic renal cell carcinoma
No full textIntroduction: Nivolumab is a recombinant, humanized monoclonal antibody that binds PD-1. The binding of PD-1 with PD-L1, expressed on antigen-presenting cells and tumor cells, suppresses the ability of T-lymphocytes to recognize and destroy tumor cells. Nivolumab reverts this inhibitory signal and has led to a significant prolongation of overall survival in patients with metastatic renal cell carcinoma (RCC). Areas covered: The rationale for immunotherapy in metastatic RCC, key immune checkpoint pathways, nivolumab pharmacodynamics, results from the main clinical trials, and predictors of response are discussed. Expert opinion: Nivolumab demonstrated a statistically significant advantage over everolimus in overall survival in metastatic RCC patients after first-line antiangiogenic therapy. Nevertheless, a number of issues remain to be resolved regarding the use of this drug in RCC. It is now imperative to identify which patients can benefit most from immunotherapy and studies are ongoing to define its role in other settings and/or in combinations with antiCTLA4 or antiangiogenic drugs
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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