197,382 research outputs found
A32 A33 A34 A. Bizzarri, P. Crupi, S. de Lorenzo, and M. Loddo Thermal effects on the time occurrence of earthquake failures: a deterministic approach.
Synthesis and antiproliferative activity of 3-aryl-2-(1H-benzotriazol-1-yl)acrylonitriles. Part III
A new series of 30 3-aryl-2-(1H-benzotriazol-1-yl)acrylonitriles were synthesized and tested for biological activity as part of our research in the antimicrobial and antitumor fields. In particular, title compounds were evaluated in vitro against representative strains of Gram-positive and Gram-negative bacteria (S. aureus, Salmonella spp), mycobacteria (M. fortuitum, M. smegmatis ATCC 19420 and M. tuberculosis ATCC 27294), yeast and mould (C. albicans ATCC 10231 and A. fumigatus). Furthermore, their antiretroviral activity against HIV-1 was determined in MT-4 cells together with cytotoxicity. In these assays title compounds and 47 additional derivatives described previously (P. Sanna, A. Carta, M.E. Rahbar Nikookar, Eur. J. Med. Chem. 35 (2000) 535-543; P. Sanna, A. Carta, L. Gherardini, M.E. Rahbar Nikookar, Farmaco 57 (2002) 79-87) were tested for their capability to prevent MT-4 cell growth. All compounds resulted devoid of antibacterial, antifungal and anti-HIV-1 activity. In anti-mycobacterial assays several compounds resulted active (MIC(50)=6.0-70 microM) against M. tuberculosis. However, since they showed cytotoxicity against MT-4 cells at lower concentrations (CC(50)=0.05-25 microM), their anti-mycobacterial activity was not selective. For this reason, the most cytotoxic compounds were also evaluated for antiproliferative activity against a panel of human cell lines derived from both hematological and solid tumors. Compound 34 resulted the most potent compound against the above human tumor-derived cell lines
AR and VR in cultural institutions
The use of augmented, virtual and mixed reality (AR/VR/MR) to experience and perceive cultural heritage is less adopted by museums, libraries, archives and cultural institutions than other fields. There may be concerns that AR/VR have the potential to stop visitors from attending in person (Coates, 2020). However, in 2020, many museums have started to offer virtual tours of their collections during the global COVID-19 pandemic. This, in fact, has forced in different moments the closure of most museums and institutions. In the following reading, the difference between those digital technologies and why cultural institutions are using them now will be described.Heritage & Value
The spectral analysis of voltage measurements for the interpretation of dipole geoelectrical soundings in low resistivity geothermal areas
The spectral analysis of voltage measurements for the interpretation of dipole geoelectrical soundings in low resistivity geothermal areas
Aspects of Magnetic Data Processing
The presence of noisy contributions such as spikes, stripes and zigzag effects in magnetic data
visualization represents the most common flaw that may degrade the image, rendering the correct
detection and identification of archaeological features very uncertain. In order to overcome this
serious disadvantage, a software package has been developed by implementing very simple
algorithms based on statistical criteria. Some applications to field data are shown and discussed
in order to demonstrate the program’s ability to remove or minimize these undesired contributions.
The results are very satisfactory: high-quality digital raster images may be produced
3-D density model of Mt. Etna volcano (Southern Italy)
A detailed density model of Mt. Etna and its surrounding areas has been evaluated using a 3-D inversion of the gravimetric data acquired in the 1980's. Several high-density and low-density bodies are found, penetrating from shallow depths as far down as 12 km bsl. A positive correlation (in terms of location, extent, density, and velocity) is established between several anomalies of the density model and features identified in previously published seismic tomographies. A prominent high-density body extending
down to 7 km bsl is recognized in the southern part of the Valle del Bove, and interpreted as a solidified magmatic intrusion. On the western boundary of this anomaly, a low-density body is interpreted as a bubble and liquid magma mixture. Outside the central area, three other high-density anomalies are imaged and attributed to the earliest phases of volcanic activity in the area. Several interesting low-density anomalies are also identified and correlated with known fault lines and other structural features of the region
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