713 research outputs found
Inter-generational family support provided by older people in Indonesia
No full textMost social research on ageing in Asia has focused on the support provided by adult children to their parents, and thereby suggests that as a matter of course older people are in need of support. This paper offers a different perspective. Drawing on ethnographic and quantitative data from a village in East Java, it examines the extent of older people's dependence on others and highlights the material and practical contributions that they make to their families. It is shown that only a minority of older people are reliant on children or grandchildren for their daily survival. In the majority of cases, the net flow of inter-generational support is either downwards – from old to young – or balanced. Far from merely assisting with childcare and domestic tasks, older people are often the economic pillars of multi-generational families. Pension and agricultural incomes serve to secure the livelihoods of whole family networks, and the accumulated wealth of older parents is crucial for launching children into economic independence and underwriting their risks. Parental generosity does not generally elicit commensurate reciprocal support when it is needed, leaving many people vulnerable towards the end of their lives
Correction to: Rare variants in KDR, encoding VEGF Receptor 2, are associated with tetralogy of Fallot (Genetics in Medicine, (2021), 23, 10, (1952-1960), 10.1038/s41436-021-01212-y)
No full textDue to a processing error the author’s Doris Škorić-Milosavljević, Najim Lahrouchi, Alex V. Postma, Connie R. Bezzina were assigned to affiliation 38. However, affiliation 38 does not exist. In addition, the affiliations of Najim Lahrouchi, Elisabeth M. Lodder, and Connie R. Bezzina should be number 1 instead of number 2. The correct affiliation is Department of Clinical and Experimental Cardiology, Amsterdam University Medical Center, Amsterdam, The Netherlands. The original article has been corrected
Correction: Electromagnetic-Guided Bedside Placement of Nasoenteral Feeding Tubes by Nurses Is Non-Inferior to Endoscopic Placement by Gastroenterologists: A Multicenter Randomized Controlled Trial. (American Journal of Gastroenterology 2019 (114) (1012) DOI: 10.1038/ajg.2016.224)
No full textIn the August 2016 issue of The American Journal of Gastroenterology, in Electromagnetic-Guided Bedside Placement of Nasoenteral Feeding Tubes by Nurses Is Non-Inferior to Endoscopic Placement by Gastroenterologists: A Multicenter Randomized Controlled Trial the authors report a misspelling of an author's name in the author list. Author Elisabeth M. Mathus- Vliegent should have been written as Elisabeth M. Mathus-Vliegen
A History of HABS and HAER in Oregon 1933-1983; a program in observance of the 50th anniversary of the founding of the Historic American Building Survey.
No full textTypescript of a two-part presentation commemorating a half-century of documenting Oregon's architectural heritage through the Historic American Building Survey.
Consists of "Part I, The American Institute of Architects and the Historic American Buildings Survey in Oregon 1930-1940," by Elisabeth Walton Potter, Oregon State Historic Preservation Office, Salem, Oregon, and "Part II, Historic American Buildings Survey and the Historic American Engineer Record to the Present Day," by Alfred M. Staehli, A. I. A., Portland, Oregon.
Digitized from a copy provided with permission to publish by author Elisabeth Walton Potter, member of the Marion Dean Ross / Pacific Northwest Chapter of the Society of Architectural Historians.National Park Service, the Historic Preservation League of Oregon, the Oregon Committee for the Humanities, the American Institute of Architect
Princess Elisabeth Research Station at Antarctica: Renewable Energy Systems design, simulation and optimization
No full textThe Earth’s climate is changing. A better understanding on the climate mechanism is essential for future sustainable development. As Antarctica has an important role in the Earth system, a new Belgian research station - named Princess Elisabeth - is currently under construction in the Sør Rondane mountains (Droning Maud Land, East Antarctica). The Princess Elisabeth station is unique in its conception. It is only manned during the austral summer, but remains operational for full year monitoring. In addition, it aims at minimum environmental impact and the highest energy and waste efficiency, fundamental issues in the Antarctic Environmental Protocol. The objective of the energy concept is a 95% sustainable hybrid system consisting of solar and wind power, combined with electrical and thermal storage. A diesel system is mainly foreseen as back-up in emergency situations. This research investigates the feasibility of the energy concept and the component sizing of the hybrid system. In addition the sensitivity of the design is evaluated on the wind variation as wind power generates most of the energy. For this purpose, a synthetic wind series is created (first order Markov chain) and combined with long term observations of other polar stations. Finally, the current design is evaluated under the assumption the station is permanently manned. A dynamical simulation tool is developed to validate the design decisions. The hybrid system consists of 6 small wind turbines of 6 kW each, a 50 kWp photovoltaic system, a 6000 Ah battery bank (VRLA) and 2 back-up diesel generators of 35 kW each. For the thermal applications, 21 m2 flat solar thermal collectors and 1.5 m3 heat storage is foreseen. To keep the station up and running under normal conditions, the annual diesel consumption ranges between 1750 and 1250 litres, depending on the wind climate. 97% of the energy originates from renewable sources, which makes the Princess Elisabeth station the most environmental friendly manned polar station. The design is a benchmark for future polar stations. If the station is permanently manned, annual diesel consumption ranges from 17000 to 14000 litres. The renewable energy fraction is reduced to approximately 72%. Sensitivity analysis showed further diesel reduction is possible by adding wind turbines and electrical storage capacity; however the marginal gain is limited. Significant reduction on the loads is needed to achieve the low emission objective. Specific attention is needed on the generator selection and battery control algorithm if the station is manned permanently.Aerospace Engineerin
Understanding cardiac electrical phenotypes in the genomic era
No full textSudden cardiac death (SCD) is defined as unexpected death due to a cardiac cause. It most often results from life-threatening ventricular fibrillation (VF) and ranks among the most common causes of death worldwide, with an incidence in the community varying between 0.6 and >1.4 per 1,000 individuals. Because SCD mostly occurs in individuals without previously known cardiac disease, the identification of patients at risk for SCD and implementation of preventive measures could save many lives. The etiology of SCD is complex and susceptibility to SCD is likely governed by a combination of inherited and environmental factors. The identification of genetic factors that modulate risk for sudden cardiac arrest (SCA) is important as it allows the pre-symptomatic identification of individuals at risk for SCA. The identification of such genetic factors also provides molecular leads for mechanistic studies that may in turn lead to better-targeted therapies. Similarly, as the electrocardiogram (ECG) reflects the electrical activity of the heart (and is instrumental for the diagnosis of many cardiac disorders), a deep understanding of molecular factors that modulate the different ECG parameters is pertinent. This thesis has accordingly focused on the identification of novel genes and genetic variants that (i) are associated with cardiac disease and SCD in affected families, or (ii) modulate ECG parameters. The thesis primarily focused on the genetics of cardiac electrical phenotypes (a word that stems from the Greek words phainein meaning "to show" and typos meaning "type"). To achieve this aim we used a broad range of state-of-the-art technologies and experimental approaches ranging from human genetic studies to studies in genetically engineered mice
Correction for Khan et al., Global selective sweep of a highly inbred genome of the cattle parasiteNeospora caninum
No full textThe authors note three author names appeared incorrectly. The author name Sarah M. Latham should instead appear as Sophia M. Latham, the author name Elizabeth A. Innes should instead appear as Elisabeth A. Innes, and the author name Johnathan M. Wastling should instead appear as Jonathan M. Wastling. The corrected author line appears below. The online version has been corrected. The authors also note that the author contributions footnote appeared incorrectly. Sophia M. Latham should be credited with designing research, performing research, and contributing new reagents/analytic tools. The corrected author contributions footnote appears below. Asis Khan, Ayako Wendy Fujita, Nadine Randle, Javier Regidor-Cerrillo, Jahangheer S. Shaik, Kui Shen, Andrew J. Oler, Mariam Quinones, Sophia M. Latham, Bartholomew D. Akanmori, Sarah Cleaveland, Elisabeth A. Innes, Una Ryan, Jan Slapeta, Gereon Schares, Luis M. Ortega-Mora, Jitender P. Dubey, Jonathan M. Wastling, and Michael E. Grigg Author contributions: A.W.F., S.M.L., J.P.D., J.M.W., and M.E.G. designed research; A.K., A.W.F., N.R., and S.M.L. performed research; A.K., J.R.-C., J.S.S., K.S., A.J.O., M.Q., S.M.L., B.D.A., S.C., E.A.I., U.R., J.S., G.S., L.M.O.-M., J.P.D., J.M.W., and M.E.G. contributed new reagents/analytic tools; A.K., A.W.F., N.R., and M.E.G. analyzed data; and A.K., J.P.D., J.M.W., and M.E.G. wrote the paper
Mouse models in Arrhythmogenic Right Ventricular Cardiomyopathy
No full textArrhythmogenic right ventricular cardiomyopathy (ARVC) is a heart muscle disorder characterized by fibrofatty replacement of cardiomyocytes. The cardinal manifestations are arrhythmias, sudden cardiac death and seldom heart failure. Mutations in genes encoding desmosomal proteins and their interaction partners have been implicated in the pathogenesis of ARVC and it is now widely accepted that ARVC is a disease caused by abnormal cell-cell adhesion due to defects in desmosomes. The mechanism(s) by which mutations in desmosomal proteins lead to fibro-fatty replacement remains to be fully elucidated. To this aim over the last 10 years different transgenic and targeted mouse models have been developed, these models and what they have taught us will be discussed in this review
Explaining the Relevance of Court Decisions to Laymen
No full textIn the context of intelligent disclosure of case law, we report on our findings with respect to the presentation of relevant court decisions back to the laymen users. For this presentation we first localize the relevant legal concepts in the cases using shallow NLP techniques. Hereafter we investigated the use of techniques from the field of recommender systems, i.e. keyword style explanation and influence style explanation, to present the cases to the user in an understandable way. In order to find out if we succeeded in that respect, we conducted a small user satisfaction research. It shows promising results, and gives us some directions for future research
Correction: Effects of cancer screening restart strategies after COVID-19 disruption
No full textThe original version of this article unfortunately contained a mistake in an author name. Elleke F. P. Peterse should be changed to Elisabeth F. P. Peterse. The authors apologize for the oversight. The original article has been correcte
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