1,720,969 research outputs found
Filling the Lacunae in ancient Latin inscriptions
No full textInscriptions are a testimony to the past but their poor condition, caused by the deterioration of the material on which they are engraved upon, often makes them partially or completely illegible. The process of restoring these inscriptions is time-consuming and requires the involvement of an expert epigraphist. It is possible to speed-up this process by adopting a semi-automatic assisting tool based on deep neural networks. This work describes a methodology, from the acquisition of the inscriptions to the description of four possible approaches, to predict the missing text in a Latin inscription, that our research team plans to implement in the near future as part of an interdisciplinary research project
L'interessamento polmonare in corso di fermato/polimiosite e di connettivite mista.
No full textnot avaibl
Il neuroimaging funzionale nella valutazione del coinvolgimento neurologico in corso di lupus eritematoso sistemico. Risultati preliminari [The evaluation of neuropsychiatric lupus erythematosus by functional neuroimaging. Preliminary results]
No full textObjective: The aim of this study was to investigate the performance of functional neuro-imaging for describe neurological involvement in Lupus Erithematosus Systemicus. Methods. 20 SLE patients were included into this study (18 females / 2 males). Median age was 40.5 years (range 16 –66 ys), 9 patients with a clear neurological involvement, 7 with aspecific neurological symptoms and 4 were asymptomatics, according to 1999 ACR Classification. All patients were underwent to conventional resonance imaging (RMFLAIR), RM perfusion ( RM-PWI), RM diffusion (RM-DWI) and cerebral SPECT. The RM techniques was performed using a 1 Tesla “Signa-Horizon” Tomograph by General Eletric: The data analysis was performed from two indipendent neuroradiologist and than trough coordinated evalutation after coregistration of acquired volumes. Results: In 11/20 patients (55%) lesions were demonstrated in RM-FLAIR evaluation, more frequent in cases with focal symptoms than in diffuse. RM-PWI was positive in 50% of cases. SPECT analysis was altered in 85 % of patients. In all patients RM-DWI evaluation was negative. 5 of 29 lesional areas (3 patients) showed by SPECT analysis were positive in RM-PWI. None of them was positive in RM-FLAIR study. After coordinated evaluation of RM-FLAIR, SPECT and RM-PWI, 7 findings were considered false positive. 6 Of patients with negative RM-FLAIR were positive in SPECT and 3 in RM-PWI. Only 1 patient was positive in SPECT and RM-PWI. Conclusions: According to the literature, the RM-FLAIR is a very sensitive procedure to describe the lesional charge, especially in patients with focal symptoms. All lesions was considered as stable outcomes due to negativity of RM-DWI analysis. The SPECT is a sensitive technique to individuate cerebral areas of altered perfusion. The coregistration seems to be an helpful method to improve the explanation of uncertain cases. e the sections are prepared for the microscopic analysis of the various histomorphometric parameters
L’amiloide e l’amiloidosi: classificazione, caratteristiche clinico-patogenetiche, orientamenti diagnostico-terapeutici.
No full textL'amiloidosi racchiude un gruppo eterogeneo di affezioni caratterizzate dalladeposizione extracellulare di materiale proteico a struttura fibrillare. I quadri clinici che ne derivano riflettonoil coinvolgimento degli organi colpiti. Ladiagnosi si basa sulla dimostrazione dell'amiloide tramite biopsia e successiva colorazione con Rosso Congo
Anticoagulante lupico e sindrome di Hughes.
No full textRassegno sulla fisiopatologia e la clinicadellasindrome da anticorpi antifosfolipidi
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
In patients with antisynthetase syndrome the occurrence of anti-Ro/SSA antibodies causes a more severe interstitial lung disease
No full textWe studied the clinical features and autoantibody profile in 21 patients with antisynthetase syndrome (AS) comparing to 48 patients with classical polymyositis and dermatomyositis without AS. At presentation, the AS group showed more frequently the presence of interstitial lung disease (ILD), arthritis/arthralgia, mechanic's hand and anti-Ro/SSA antibodies. Patients without AS had more frequent proximal weakness and cutaneous erythematosus rash. Interestingly, the AS patients with associated anti-Ro/SS-A antibodies seem to be predisposed to the development of a more severe ILD, expressed as HRCT total score > or = 7. During a follow up of about 3 years (range 6-110 months), the presence of anti-Jo-1 antibody alone or in association with anti-Ro/SSA did not influence survival or a more severe prognosis of ILD
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