1,720,975 research outputs found
Potential Anti-Cancer, Cytotoxic and Antioxidant of Polar and Non-Polar Extracts of Origanummajorana Linn
No full textObjective: To evaluate the anticancer and cytotoxic activity of the Origanum majorana and also to test its antioxidant potential. Methods/Statistical Analysis: The in vitro anticancer and cytotoxic activity of the Polar (PF) and Non-Polar Fraction (NPF) obtained from a total Ethanolic Extract (EE) of O. majorana were evaluated using the murine myeloma cell lines Sp2/O-Ag14 (ATCC: CRL-1581) and VERO-ATCC-CCL81. The cell viability was measured with the Colorimetric Quantification System of the Transmittance Index (CQSTI) method; a simple ANOVA of the CQSTI values of each cell line treated with the different extracts was carried out. Findings: The preliminary phytochemical analysis determined the presence of tannins, flavonoids and terpenes in the fractions. EE and PF showed a strong DPPH free radical scavenging capacity, 88,8 and 85.9% uptake, respectively. EE and PF displayed promising anti anticancer activity for both cell lines, so, EE, PF and NPF concentrations that produced 50% cell viability included 5.7 mg/mL, 5.8 mg/mL and 35.8 mg/mL, respectively. Application/Improvements: For the first time it is shown that the PF from O. majoranaa low concentrations affected myeloma cells but not VERO cells. These results indicate that this fraction has an anticancer activity. In addition, our results demonstrated that the PF has a high phenolic content, this could be related to its cytotoxic activity.Fil: Soto Rueda, Eliana Marcela. Universidad del Quindio; Colombia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones en Ciencias de la Tierra. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Centro de Investigaciones en Ciencias de la Tierra; ArgentinaFil: Restrepo, Rodrigo Andrés. Universidad del Quindio; ColombiaFil: Loango, Nelsy. Universidad del Quindio; ColombiaFil: Restrepo, Beatriz. Universidad del Quindio; ColombiaFil: Landazuri, Patricia. Universidad del Quindio; ColombiaFil: Rai, Mahendra. Amravati University; Indi
Removal of hexavalent chromium from wastewater using microorganisms adapted to chromium-rich media
Full text linkLos problemas de contaminación de acuíferos a nivel mundial son motivo de preocupación y requieren métodos efi caces de remediación que permitan minimizar el impacto ambiental generado por vertimientos industriales y domésticos. En el presente estudio se determinó la capacidad de remoción de Cr6+ en bacterias y levaduras adaptadas a concentraciones altas de este metal. Métodos: Los ensayos de remoción se llevaron a cabo en medio de cultivo BHI y en agua residual (AR) a los cuales se les adicionó dicromato de potasio (K2Cr2O7). Resultados: Las bacterias y levaduras aisladas y adaptadas a Cr6+ demostraron ser reductoras de este metal. Los aislados bacterianos Raoultella sp, Serratia sp y Klebsiella sp presentaron mayor reducción de Cr6+ en AR alcanzando el 100% de reducción de cromo en 30 horas, estos tres aislados se destacaron por su capacidad de reducir Cr6+ tanto en medio de cultivo como en agua residual en todas las concentraciones de K2Cr2O7 evaluadas. Los aislados levaduriformes Candida Tropicalis, Candida Famata y Cryptococus neoformans no presentaron diferencias significativas con el control en el ensayo de reducción del metal en AR con diferentes concentraciones de Cr6+. Conclusiones: La capacidad de reducción del Cr6+, así como el crecimiento bacteriano en condiciones altas de este metal, permiten proponer a Klebsiella sp, Raoultella sp, y Serratia sp como microorganismos promisorio para la bioremediación de sitios contaminados con Cr6+ a escala real.Global aquifer contamination problems are a cause for concern and require effective remediation methods to minimize the environmental impact generated by industrial and domestic dumping. In the present study, the ability to remove Cr6+ from bacteria and yeasts adapted to high concentrations of this metal was determined.Methods: Removal tests were carried out in BHI culture medium and in residual water to which potassium dichromate (K2Cr2O7) was added. Results: Bacteria and yeasts isolated and adapted to Cr6+ were shown to be reductive of this metal. The bacterial isolates Raoultella sp, Serratia sp and Klebsiella sp presented higher reduction of Cr6+ in residual water (AR) reaching 100% reduction of chromium in 30 hours, these three isolates were highlighted by their ability to reduce Cr6+ in both culture medium As in residual water at all concentrations of K2Cr2O7 evaluated. The yeast isolates Candida Tropicalis, Candida Famata and Cryptococus neoformans did not present signifi cant differences with the control in the reduction test of the metal in RA with different concentrations of Cr6+. Conclusions: The ability of Cr6+ reduction, as well as the bacterial growth in high conditions of this metal, allow to propose Klebsiella sp, Raoultella sp, and Serratia sp as promising microorganisms for the bioremediation of sites contaminated with Cr6+ in real scale.Fil: Soto Rueda, Eliana Marcela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones en Ciencias de la Tierra. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Centro de Investigaciones en Ciencias de la Tierra; ArgentinaFil: Landazuri, Patricia. Grupo de Investigación Gecavyme; ColombiaFil: Loango, Nelsy. Grupo de Investigación Gecavyme; Colombi
Niveles de excreción urinaria de yodo en escolares del quindío, 2006–2007
Full text linkObjetivo El estado nutricional de yodo se mide por la concentración de yodo urinario y permite evaluar los riesgos por deficiencia o aumento.Estudiar la frecuencia del riesgo de desordenes por deficiencia o por más de una adecuada ingesta de yodo en escolares del Quindío.Métodos La concentración de yodo urinario se midió en una muestra casual de orina tomada en cada sujeto entre el 2006-2007.Resultados En 444 muestras analizadas, la mediana de yoduria fue de 272,4 μg/L;11,9 % de los escolares tenían yoduria normal, 28,8 % presentaron déficit de yodo, de estos 11,5 % tenían déficit severo, 12,6 % déficit moderado y 4,7 % déficit leve. 59,3 % presentaron riesgo por ingesta excesiva de yodo. El rango de déficit de yodo en los niños fue de 31 % y en las niñas 26,6 % sin diferencia significativa, tampoco se encontró diferencia significativa con la edad, pero si entre los estratos (p and lt;0,000). Los municipios de las zonas rurales presentaron 100% de déficit de yodo (medianas and lt;100 ug/L), mientras los de la zona urbana (Armenia, Tebaida y El Caimo) presentaron excesiva ingesta de yodo.Conclusiones la población estudiada mostró severas deficiencias (zonas rurales) y excesiva ingesta de yodo (población urbana), sugiriendo ausencia o pobre control del programa de yodación y una exposición adicional a elementos causantes de desordenes de yodo. Se requiere un programa para el seguimiento de los desordenes de yodo en la población escolar estudiada
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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