9,938 research outputs found
Local Author Book Talk: Meet D.M. Pulley author of The Dead Key
No full textLocal Author D.M. Pulley, author of The Dead Key.
2014 Winner — Amazon Breakthrough Novel Award — Grand Prize and Mystery & Thriller Fiction Winner. It’s 1998, and for years the old First Bank of Cleveland has sat abandoned, perfectly preserved, its secrets only speculated on by the outside world.--Source Amazon.com
These books and all Friends of the Library 2021/2022 book selections are on sale at Viking Outfitters, located in the CSU Student Center
Canceled: Local Author Book Talk: Meet D.M. Pulley author of The Dead Key
No full textThis event has been canceled due to the Coronavirus.
Meet Local Author D.M. Pulley, author of The Dead Key.
2014 Winner — Amazon Breakthrough Novel Award — Grand Prize and Mystery & Thriller Fiction Winner. It’s 1998, and for years the old First Bank of Cleveland has sat abandoned, perfectly preserved, its secrets only speculated on by the outside world.--Source Amazon.com
The books titled The Dead Key, No one’s Home, Unclaimed Victim, and The Buried Book will be available for sale by Viking Outfitters at the event. These books and all Friends of the Library 2019/2020 book selections are on sale at Viking Outfitters, located in the CSU Student Center
Optimising the assessment of cerebral autoregulation from black box models
Full text linkCerebral autoregulation (CA) mechanisms maintain blood flow approximately stable despite changes in arterial blood pressure. Mathematical models that characterise this system have been used extensively in the quantitative assessment of function/impairment of CA. Using spontaneous fluctuations in arterial blood pressure (ABP) as input and cerebral blood flow velocity (CBFV) as output, the autoregulatory mechanism can be modelled using linear and non-linear approaches, from which indexes can be extracted to provide an overall assessment of CA. Previous studies have considered a single – or at most a couple of measures, making it difficult to compare the performance of different CA parameters. We compare the performance of established autoregulatory parameters and propose novel measures. The key objective is to identify which model and index can best distinguish between normal and impaired CA. To this end 26 recordings of ABP and CBFV from normocapnia and hypercapnia (which temporarily impairs CA) in 13 healthy adults were analysed. In the absence of a ‘gold’ standard for the study of dynamic CA, lower inter- and intra-subject variability of the parameters in relation to the difference between normo- and hypercapnia were considered as criteria for identifying improved measures of CA. Significantly improved performance compared to some conventional approaches was achieved, with the simplest method emerging as probably the most promising for future studies
Pinnularia molderii fm. spitsbergensis D. M. Williams, Bing Liu & Taxbock 2022, nom. nov.
No full textPinnularia molderii f. spitsbergensis D.M. Williams, Bing Liu & Taxböck nom. nov. ≡ Pinnularia hustedtii f. spitsbergensis Foged 1981: 148, pl. 42, fig. 8 (Foged 1964: 122, “ Pinnularia hustedtii forma”) Type:— Alaska, Spitzbergen, C 466/1963, holotype; ANSP GC 64404, isotype (Mahoney & Reimer 1997: 170).Published as part of Williams, David M., Liu, Bing & Taxböck, Lukas, 2022, Pinnularia hustedtii (Bacillariophyta): Notes on specimens from Wuling Mountains, China and from type material, pp. 294-300 in Phytotaxa 536 (3) on page 299, DOI: 10.11646/phytotaxa.536.3.10, http://zenodo.org/record/633185
Tracing the dynamics of the cerebral autoregulation response to step-wise changes in PaCO2
No full textHigh spontaneous variability in blood pressure helps in assessing blood flow control
No full textCerebral autoregulation maintains a relatively constant blood flow despite changes of blood pressure in the brain. Linear models have been extensively applied to identify this mechanism, using spontaneous arterial blood pressure (ABP) fluctuation as input and cerebral blood flow velocity (CBFV) change as output. Although valuable measurements have been achieved by these models, accuracy and consistency are of great concern due to the large variability of results. We therefore investigated whether more reliable measurements can be achieved by selecting only those recordings (or parts of recordings) with relatively high spontaneous variability of ABP. Twenty-four recordings, 7 from hypercapnia and 17 from normocapnia, of ABP and CBFV from 9 healthy adults were analyzed. Two conventional autoregulatory parameters were used to assess cerebral autoregulation. In the absence of a 'gold' standard for the study of dynamic cerebral autoregulation, lower variability of the parameters and higher correlation with pCO2 were considered as criteria for identifying improved measures of autoregulation. Both significantly lower variability of the parameters, and higher correlation between the parameters and pCO2 were achieved from the data with higher variability of blood pressure. We therefore conclude that ABP with high variability may effectively stimulate regulatory response in blood flow resulting in improved assessment of cerebral autoregulation
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