3 research outputs found
IER-SICH Nomogram to Predict Symptomatic Intracerebral Hemorrhage After Thrombectomy for Stroke
No full textBackground and Purpose - As a reliable scoring system to detect the risk of symptomatic intracerebral hemorrhage after thrombectomy for ischemic stroke is not yet available, we developed a nomogram for predicting symptomatic intracerebral hemorrhage in patients with large vessel occlusion in the anterior circulation who received bridging of thrombectomy with intravenous thrombolysis (training set), and to validate the model by using a cohort of patients treated with direct thrombectomy (test set). Methods - We conducted a cohort study on prospectively collected data from 3714 patients enrolled in the IER (Italian Registry of Endovascular Stroke Treatment in Acute Stroke). Symptomatic intracerebral hemorrhage was defined as any type of intracerebral hemorrhage with increase of ≥4 National Institutes of Health Stroke Scale score points from baseline ≤24 hours or death. Based on multivariate logistic models, the nomogram was generated. We assessed the discriminative performance by using the area under the receiver operating characteristic curve. Results - National Institutes of Health Stroke Scale score, onset-to-end procedure time, age, unsuccessful recanalization, and Careggi collateral score composed the IER-SICH nomogram. After removing Careggi collateral score from the first model, a second model including Alberta Stroke Program Early CT Score was developed. The area under the receiver operating characteristic curve of the IER-SICH nomogram was 0.778 in the training set (n=492) and 0.709 in the test set (n=399). The area under the receiver operating characteristic curve of the second model was 0.733 in the training set (n=988) and 0.685 in the test set (n=779). Conclusions - The IER-SICH nomogram is the first model developed and validated for predicting symptomatic intracerebral hemorrhage after thrombectomy. It may provide indications on early identification of patients for more or less postprocedural intensive management
Les assassinats royaux dans la Chronique française de Guillaume Cretin
No full textInternational audienceLe Recueil sommaire des cronicques françoises (Paris, BnF, fr 2817- 2822) was presented to Francis I by its author, one of the leaders of the “Grands Rhetoriqueurs”, Guillaume Cretin. Selected for the 89 paintings were major representatives of Parisian illumination, including Jean Pichore, Jean Coene IV, and their collaborators. They excel in depicting a rich narrative and they portray royal assassinations as repellent, in line with the moral, political, and religious project of the work.Le Recueil sommaire des cronicques françoises (Paris, BnF, fr 2817-2822) a été offert à François Ier par son auteur, un des chefs de file des Grands rhétoriqueurs, Guillaume Cretin. Ont été retenus pour les 89 peintures des représentants majeurs de l’enluminure parisienne Jean Pichore, Jean Coene IV et leurs collaborateurs. Ils excellent à rendre compte d’un récit foisonnant et font des assassinats royaux des repoussoirs, en adéquation avec le projet moral, politique et religieux de l’œuvre
Review of Le Cardinal Jean Du Bellay : diplomatie et culture dans l'Europe de la Renaissance by Michon, C. and Petris, L.
No full textCardinal Jean Du Bellay (1498–1560) is remembered for his patronage of Rabelais and his kinsman Joachim; he was also an accomplished Latin poet, a keen collector of ancient artwork, and a prominent diplomatic emissary for François Ier and Henri II. This volume stems from an interdisciplinary conference prompted by the ongoing edition of Du Bellay's correspondence by Loris Petris, Rémy Scheurer, and their collaborators. A first section retraces Du Bellay's roots in a family of provincial nobles who, over three to four generations, increasingly provided service to the royal court (Laurent Bourquin); his evolving relations with the German princes and the Holy Roman Empire (Thomas Nicklas); and his role in defending France's interests with respect to Reformation England (David Potter). From an ecclesiastical angle, Cédric Michon, Alain Tallon, and Scheurer study the cardinal's benefices in France; his advocacy of the evangelical movement; and his accession to the deanship of the Sacred College. Five chapters review the man of letters: Marie Barral-Baron considers the prelate as a reader of Erasmus, while Perrine Galand, Richard Cooper, and David Amherdt highlight different aspects of his poetry. Nathalie Guillaud reflects on the reasons why the cardinal, unlike his brother Guillaume, did not take up historiography. A fourth cluster investigates the cardinal's sojourn in Rome, namely his household and friends (Petris); the gardens of his villa (Flaminia Bardati and Renata Samperi); and his interaction with the contemporary trade in antiquities (Barbara Furlotti). Next, Carmelo Occhipinti considers French perceptions of the Rome of Julius III and Michelangelo, while Guido Rebecchini revisits the volatile relationship between Du Bellay and Cardinal Ippolito de' Medici, pointing to the role of Giovan Francesco Valier, Ippolito's Venetian-born secretary who spied for Du Bellay. Guillaume Alonge, finally, discusses Ludovico di Canossa, Bishop of Bayeux, and the secret agent Giovan Gioacchino da Passano, both of whom belonged to the Du Bellay brothers' international network. The collective bibliography, handsome layout, and wealth of illustrations enhance the volume's unity, while five appendices give access to significant archival and literary evidence: (i) an edition (based on BnF MS Dupuy 810) and French translation of Du Bellay's Silva Langaeana, by Amherdt; (ii) a diplomatic Mémoire sur les affaires d'Angleterre (1539–1540), edited by Guillaud; (iii) three archival documents, including his will; (iv) two lists of the cardinal's household; and (v) three inventories, of his statuary, chapel, and wardrobe — all by Petris. Du Bellay emerges from this 360-degree appraisal a much more polyvalent political and cultural figure, albeit one with varying influence. Notwithstanding some nit-pickings (such as the bibliography's listing of Renata Ago's Economia barocca under R, the impractical endnotes to the Annexes, or the mostly cursory references to Joachim Du Bellay), this multi-faceted book will constitute an obligatory port of call for any future discussions of the cardinal and his world
