1,720,984 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Correction: Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry(PLoS ONE (2019) 14:10(e0223804)DOI: 10.1371/journal.pone.0223804)

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    The third author’s name is spelled incorrectly. The correct name is: Lisa Di Marcantonio. The correct citation is: Marotta F, Garofolo G, Di Marcantonio L, Di Serafino G, Neri D, Romantini R, et al. (2019) Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry. PLoS ONE 14 (10): e0223804. https://doi.org/10.1371/journal.pone.0223804

    DECELLULARIZED AND ENGINEERED TENDONS WITH SHEEP AMNIOTIC EPITHELIAL STEM CELLS ALLO-TRANSPLANTED IN EXPERIMENTALLY INDUCED SHEEP TENDON RESECTION

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    Achilles tendinopathy affects athletes, recreational exercisers and even inactive people. The tendon has a poor ability to regenerate, and even after healing the breaking point results in the scar tissue formation that impairs its mechanical properties. To overcome to the poor results of the current therapies, stem cell based treatments appears to be an innovative solution. In this context, amniotic epithelial stem cells (AECs) are receiving growing interest from scientist because of their pluripotency, easy accessibility, low immunogenicity and immunomodulatory properties making them ideal candidates in allo and xenotransplantation setting for stem cell therapy approaches. Preclinical model studies on experimentally tendon defects confirmed ovine AECs (oAECs) direct and indirect role in tendon regeneration also modulating the inflammatory response during tendon healing. In order to improve the partial or total tendon resection with the use of oAECs, this research aims to investigate the allo-transplantation of biological decellularized tendons or biocompatible electrospun scaffolds, both engineered with oAECs. Before starting with the above aims, to confirm oAECs in vitro capabilities to modulate the inflammatory response, this research focused on their in vivo immunomodulatory ability when transplanted into an allogeneic recipient. In particular, we investigated the allotransplanted oAECs immunomodulatory role during the early regeneration phase of sheep tendon experimentally induced defects. Specifically, it was evaluated the oAECs role exerted on macrophages (Mφ), in particular on M1Mφ pro-inflammatory and M2Mφ anti-inflammatory subpopulations involved in tissue regeneration. The in vivo experiments results indicate the oAECs modulate the M1Mφ pro-inflammatory switching toward the M2Mφ regenerative phenotype in the tendon lesion areas. Then, in this project, it has been developed a decellularization technique to obtain decellularized tendons that keep the extracellular matrix (ECM) bioactive components for their use as biological scaffolds for oAECs colonization. We conducted comparative studies of decellularization techniques either using detergents or decellularization of fetal tendon explants cultured in incubator, allowing cells to abandon the tissue and colonize the petri dish. The results on biological scaffolds indicated that the detergent decellularization method was effective for the complete cell components elimination but need to be improved in order to maintain the ECM bioactive components, while the decellularization culture method adopted has demonstrated to achieve a good conservation of the ECM components, but tendons were not completely decellularized. Thus, only the technique with detergents allowed obtaining decellularized tendons that soon will be cultured with oAECs obtaining biological engineered scaffolds. We also evaluated oAECs in vitro biocompatibility on biodegradable polymers, in particular on three electrospun biomaterials used for medical devices, Polylactic acid (PLA), Polycaprolactone (PCL), polylactic acid-co-glycolic (PLGA). This phase of the research was possible thanks to the collaboration of Dr. Tammaro (ENEA Research Center- Brindisi Italy).These scaffolds were treated with 3 different sterilization methods: 70% ethanol, ethylene oxide, ethanol 70% rehydrated for 24 hours, in order to verify which one was the best technique for the analysed scaffolds in terms of ultrastructural morphology. Ovine AECs biocompatibility on PLGA sterilized in ethanol 70% rehydrated revealed to be the best in terms of scaffolds ultrastructural stability, cell colonization and spatial organization around the microfibers. Tissue engineering represent a promising approach in regenerative medicine based on the synergy between biocompatible scaffolds miming ECM and oAECs, although the realization of the ideal scaffold should consider several factors, such as chemical and ultrastructural composition prior their use in allo- and xeno-transplantation setting. Next research will be focused on using aligned fibers PLGA scaffolds (in collaboration with Dr. Tammaro and INNOVENT enterprise), that mimic tendon structure, taking advantage of oAECs capacity to differentiate in tenocyte like cell and subsequently using PLGA engineered scaffolds on experimental of partial or total tendon resection preclinical studies to verify their augmented regenerative potential

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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