266 research outputs found

    Cheney, Matthiessen, and Me

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    Essay about life partners Russell Cheney, the painter, and Harvard professor F. O. Matthiessen. The author, himself a gay man who grew up close to the Kittery home Cheney and Matthiessen shared, reflects on their lives and the relationship they had to hide from much of the world

    Language evolving: Notes towards a semiotic history of humanity

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    Webcast sponsored by the Irving K. Barber Learning Centre, and hosted by the Department of Language and Literacy Education and the Faculty of Education as part of the plenary session at the 37th International Systemic Functional Congress, Matthiessen poses the theme that is "language evolving". This can be interpreted either very generally or more technically. (1) Taken very generally, this could mean language changing in any of the three time-frames that have been explored in systemic functional linguistics phylogenetic change (language changing in the human species, or in human societies, over a long period of time ranging from generations to history of the human species), ontogenetic change (language changing in human individuals [seen as organisms or as persons] in the course of a lifetime, or logogenetic change (language changing in the course of the unfolding of text). (2) Taken more technically (i.e. with "evolution" in the technical sense introduced by Darwin), this means language changing phylogenetically language evolving as part of the evolution of the human species (in biological terms) and as part of the evolution of human groups (in social terms), these two being complementary aspects of human evolution. However, Matthiesson focuses on the narrower, technical sense of "language evolving". More specifically, he explores the "big history" of humans - a deep time view of human evolution in linguistic, or more generally in semiotic terms, starting with the emergence of the human line and moving up to the present.Non UBCUnreviewedPostdoctora

    Quality assurance in genetic testing: a European perspective

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    Genetic testing has moved rapidly from research to clinical use and the issues of quality have not alwaysreceived sufficient attention. In response to these needs to improve the overall quality assurance system forgenetic testing and services there have been several international initiatives that are reviewed here. Themain activities at European level towards improving the quality assurance of genetic testing are described

    Polyphony and the anxiety of influence in the fiction of Henry James

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    James's fiction, especially in the Middle Phase, centres on the figure of the artist and is characterized by, the two interrelated aspects which previous criticism has largely overlooked: the Bakhtinian 'polyphonic' -creation of 'author-thinkers'; and the conflict between ephebes and precursors, for which Harold-Bloom's concept of 'the-anxiety of influence' is the most illuminating model. Polyphony is the narrative mode, and influence is the intra-artistic, theme. These, as the Introduction to the thesis makes clear, are rehearsed in James's inaugural novel, Roderick Hudson. Rowland Mallet is an author-thinker, and his failure is caused by authorial limitations. His monologism -is impaired by his mistaking empathy for the authorial sympathy. Likewise, Hudson's failure does not arise from a mercurial temperament, but from a polyphonic shortcoming: not possessing the power of fiction to contain the fiction of power in, his mentor. And the relationships among the three artists - Gloriani, Hudson and Singleton - perfectly exemplify the Bloomian-theme. It is these two concepts, polyphony and influence, which are the major preoccupation in the Middle Phase; as, the works chosen demonstrate. These are a novella, a novel, and a number of short stories all of which have been unjustifiably neglected. Chapter One, on The Aspern Papers, argues that Tina Bordereau, far from being, the artless victim seen by many critics, actually challenges and defeats the narrator by the very form of her narrative. Her 'realist' discourse undermines his language of 'romance', and shows up its internal unstability. Chapter Two is an extensive study of the critical reception of The Tragic Muse. The most common areas of critical attention have been its contemporary topicality, its relation to previous novels on similar themes, and the possible genealogy of Gabriel Nash. Those have all missed the core of the work. - Chapter Three demonstrates how polyphony and the anxiety of influence make the novel what it really is. Influence arises from the juxtaposition of, and the wrestling between, artistic ephebes and their precursors (Nick and Nash,, Miriam and Madame Carre). The dialogic quality defined by Bakhtin is crucial to the proper, and even-handed, characterization of all, the conflicts in the novel. And since most of James's tales in the eighties and nineties -are about 'masters - and acolytes, the anxiety of influence remains central. Chapter Four is a study of 'The Author of Beltraffiol' and 'The Lesson of the Master'. Again the characters' manipulations are a crucial focus in a way that G6rard Genette's terminology helps to illuminate. The fact that the ephebe is the author-thinker emphasizes the inextricability of the Bakhtinian and the Bloomian in James. Just as polyphony offers a different focus for explicating the poetics of James's fiction; so the ephebal conflict provides the basis for a fresh perception of James's own artistic struggle

    Emerg Infect Dis

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    Influenza virus infections are a major public health threat. Vaccination is available, but unpredictable antigenic changes in circulating strains require annual modification of seasonal influenza vaccines. Vaccine effectiveness has proven limited, particularly in certain groups, such as the elderly. Moreover, preparedness for upcoming pandemics is challenging because we can predict neither the strain that will cause the next pandemic nor the severity of the pandemic. The European Union fosters research and innovation to develop novel vaccines that evoke broadly protective and long-lasting immune responses against both seasonal and pandemic influenza, underpinned by a political commitment to global public health
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