263 research outputs found
The research of \ue2Meng-ying yuan\ue2 and \ue2Ching-chung chuan tan tzu\ue2
No full textMost of the studies on \ue2Tan tzu\ue2 written by women in the Qing Dynasty mainly selected individual writer as the object, and did not investigate the thematic ideas of works from the perspective of the same family. Therefore, this study intends to choose Zheng Danruo\ue2s \ue2Meng-ying yuan\ue2 and Zhou Yingfang\ue2s \ue2Ching-chung chuan tan tzu\ue2 as the themes. The Qing Dynasty was characterized by family-based, group-oriented and regional development of talented women, and this study intends to investigate the inheritance of thematic ideas and writing style of the works of the mother and daughter. For research method, this study used text reading analysis, and probed into the data of poetry anthology, history books, local history, secret military files of writers themselves or their family and friends, in order to clarify the members and history of family. This study also investigated and compared the family-state perspective, gender perspective, and religious perspective of the two Tan tzu, in order to reflect the differences and similarities in these two works and the cultural meanings and era significance reflected in them. In addition, because Zhou Yingfan\ue2s \ue2Ching-chung chuan tan tzu\ue2 stood against the karma theory of Cai Qian\ue2s \ue2Shuo Yue Quan Chuan\ue2, this study also compared \ue2Ching-chung chuan tan tzu\ue2\ue2s acceptance and responses to \ue2 Shuo Yue Quan Chuan\ue2, in order to make up the deficiency of the studies on Yue Fei. It is hoped that the comparison on the differences and similarities of the works not only reflect the importance attached to loyalty and filial piety in the themes of \ue2Meng-ying yuan\ue2 and \ue2Ching-chung chuan tan tzu\ue2, but also emphasize how the mother and daughter endeavored to inherit the family spirit of Yimen Zheng Family
The opinions and current status about providing pharmaceutical care to the nursing home in the eastern Taiwan surveyed by questionnaire answered by the administrative officer of the facility
No full text研究背景： 護理之家每年一次的督導考核確實已將藥事服務納入評估的標準，但機構對評鑑項目及重點不易掌握。以護理之家之藥事服務相關的文獻也不多，而護理之家的住民依賴藥物的程度又是所有長照機構中最高者，因此藥事服務在未來勢必成為護理之家新興的業務，值得加以探討。
研究目的： 為了瞭解東臺灣（指宜、花、東三縣市）護理之家經營者本身對於藥事服務內涵的意見並探討現況，以期在護理之家中逐步合理地導入適合的藥事照護模式，並探討機構屬性、經營模式、及規模對藥事服務模式、內容、頻率、付費方式的影響。
研究方法： 採用問卷方式調查護理之家經營者有關機構中藥事服務的意見及執行現況，藉此獲得相關資訊，以無母數卡方檢定檢視各依變項與自變項的相關性。
研究結果及討論： 問卷回覆率64.3％（9/14），其中公營的護理之家佔回覆機構的33.33％（3/9），其都一致地認為機構藥師最好採取與醫院合作模式以專任方式任用。在藥事服務頻率方面發現所有公營之護理之家傾向應每週進行一次，由醫療院所附設且經營規模較小（≦50床者）的護理之家則傾向『每月一次』的服務頻率即可，除對服務模式及住民用藥比例的看法與機構屬性相關；藥物治療評估即藥事人員任用模式的看法則與機構經營模式相關之外，其他結果則與機構屬性、經營模式及規模無明顯相關。值得注意的是在此區域之護理之家目前提供藥事服務的頻率的現況調查結果與意見調查結果差異頗鉅。同樣地在現況調查的結果，除費用支付方式與經營模式有關之外，大多數也與機構數性、經營模式、及規模無明顯相關。
結論與建議： 單一機構很少能單獨自聘藥師提供專職藥事服務，應該有健康保險涵蓋各種長期照護的給付，以提昇社區藥局藥師參與的誘因，提昇機構的用藥品質，在服務頻率方面，『每月一次』的要求應可考慮納入評鑑內容。本研究的限制在於此區域之機構數少，故要據此結果推測全臺概況必須相當審慎。Background： Residents of nursing homes rely heavily on medication care, so pharmaceutical care plays an important role in this area of care services. The annual accreditation, which includes pharmaceutical care evaluation, for nursing home has been implemented regularly for a while, but the content and focus of evaluation still needs to be explored. Since relevant articles about pharmaceutical care in nursing home are limited, so it would deserve to be investigated.
Objective： This study surveys the administrative officer’s concept and current status of the pharmaceutical care in the nursing homes in the Eastern Taiwan. Another purpose of this study was trying to introduce a suitable model of pharmaceutical service model into the nursing home. The relationships between independent varibles such as the property of the facility, model of management, and scale of the facility (number of bed) and dependent variables such as pharmaceutical service model, items frequencies, and payment system were analyzed.
Method： Questionnaires regarding the opinions and current status of pharmaceutical services in the nursing home were sent to all of the nursing homes’s administrative offiers. The returned answers were then analyzed by non-parameter statistics about the relationships between independent variables and dependent variables.
Result and Discussion： The overall response rate of the questionnaire in this study is 64.3％（9/14）. Within the 9 responses 3 came from public nursing home, as a ratio of 33.33％. All of the administrative officers of the public nursing homes think that the model of pharmaceutical services delivered by the pharmacist assigned by cooperative hospital is the best model. In regard to frequency of providing pharmaceutical services, “once a week” is the pick of choice. The frequency became however to “once monthly” for the nursing home, which is usually affiliated with a hospital, with lesser beds (≦50). There are no significant relationships between the dependent and independent variables except service model and medication rate of the residents to the property of nursing home, and the item of pharmaceutical care and the model of installing pharmacist to the model of management. It deserved to be notified that the difference between opinion and current status about frequency of pharmaceutical services is significant. The same as in the opinion survey, there are no significant relationships between the most dependent and independent variables except payment to the business model.
Conclusion and Suggestion： Few nursing homes can afford a full-time pharmacist to deliver pharmaceutical services. There should be health insurances covering long term care in nursing home. This increases the incentive of the community pharmacist to participate in pharmaceutical services and improve the quality of medication in nursing home. Monthly pharmaceutical services may serve as an item of accreditation, and can be considered as the requirement for the nursing home. However, one should be cautious in extrapolating results of this study due to its small sampling size.目錄 Ⅳ
圖目錄 Ⅵ
表目錄 Ⅶ
附錄 97
第一章 緒論 1
前言 1
研究背景 2
研究動機 4
研究目的 7
第二章 文獻探討 8
用藥概況 10
用藥不當 12
藥師與醫師在看法上的差異 14
藥師介入的方法 15
藥事介入的好處 21
品質 21
費用 26
藥師介入的意願 30
藥事管理問題 30
藥事服務介入NH所面臨的問題 32
作業 32
給付 34
藥事服務替代方案 36
第三章 研究方法 37
研究假設 38
研究架構 38
問卷設計 40
問卷效度 42
問卷信度 43
統計分析 45
編碼簿（Code Book） 46
第四章 研究結果與討論 52
第一部份-藥事服務內涵的意見 52
機構的特質及藥事服務的模式 52
藥事服務內容 54
藥事服務的頻率 57
藥事服務的費用支付 57
第二部份-藥事服務現況的調查結果 59
藥事服務的模式 59
藥事服務內容 60
藥事服務的頻率 63
藥事服務的費用支付 64
第五章 結論與建議 64
藥事服務模式的意見 66
藥事服務的內容 68
藥事服務的頻率 70
藥事服務的費用支付 71
研究限制 72
研究建議 72
第六章 參考文獻 93
圖 目 錄
圖一、護理之家提供藥事服務內涵調查的研究架構 39
圖二、護理之家提供藥事服務之現況調查的研究架構 40
表 目 錄
表1、東臺灣護理之家名單 3
表2、第一部份問卷信度評估結果（大題部分） 74
表3-（1）、第一部份問卷信度評估結果（各子題部分） 75
表3-（2）、第一部份問卷信度評估結果（各子題部分） 76
表4、第二部份問卷信度評估結果（大題部分） 77
表5-（1）、第二部份問卷信度評估結果（各子題部分） 78
表5-（2）、第二部份問卷信度評估結果（各子題部分） 79
表6、東臺灣護理之家提供藥事服務內涵意見-機構的特質 80
表7、東臺灣護理之家提供藥事服務內涵意見及現況-用藥概況及藥事服務模式 81
表8-1、東臺灣護理之家藥事服務內涵之意見及現況-藥事服務內容 82
表8-2、東臺灣護理之家藥事服務內涵之意見及現況-藥事服務內容 83
表9、東臺灣護理之家提供藥事服務內涵的意見及現況-藥事服務頻率及費用支付 84
表10、東臺灣護理之家藥事服務內涵意見-服務模式vs.自變項-無母數卡方檢定 85
表11、東臺灣護理之家藥事服務內涵之意見-服務內容vs.自變項-無母數卡方檢定 86
表12、護理之家藥事服務之現況-服務模式、頻率vs.自變項-無母數卡方檢定 87
表13、東臺灣護理之家藥事服務之現況-服務的內容vs.自變項-無母數卡方檢定 88
表14、無母數卡方檢定後與機構屬性相關之變項＊ 89
表15-1、無母數卡方檢定後與機構經營模式相關之變項＊ 90
表15-1、無母數卡方檢定後與機構經營模式相關之變項＊ 91
表16、無母數卡方檢定後與機構規模相關之變項＊ 9
Isolation and characterization of a competence operon associated with transformation and adhesion in Helicobacter pylori
No full textModeling the effects of environmental and management variables on crop productivity
No full textSubmission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01The student, Tzu-Shun Lin, accepted the attached license on 2022-11-30 at 15:20.The student, Tzu-Shun Lin, submitted this Dissertation for approval on 2022-11-30 at 15:22.This Dissertation was approved for publication on 2022-12-01 at 07:24.DSpace SAF Submission Ingestion Package generated from Vireo submission #18702 on 2023-04-12 at 11:36:02Crop growth is influenced by changes in environmental conditions and agricultural management practices. Crop growth also influences the atmosphere and in turn, feedback on the planted crop. Understanding climate change and land management and their interactions with crops are of particular interest as they are the key to assessing future food productivity under changing climate. This dissertation aims for the productivity of various crops, including corn (maize), soybean, rice, and bioenergy grasses, and their drivers and feedback processes by developing a data-model integrated framework and applying it at the site, regional and global scales. Chapter 1 of the dissertation introduces the overall objectives and method. Chapter 2 examines the effects of the past and future changes in climate, atmospheric CO2 concentration, irrigation, heat stress, and N on global corn and soybean over the 20th and 21st centuries under two future scenarios at 0.5-degree spatial resolution. To characterize and assess corn and soybean yield, I extend and evaluate crop-specific biophysical processes and feedbacks in a land surface model, the Integrated Science Assessment Model (ISAM), including planting time, heat stress as a function of canopy temperature, seeding rates, and residue management, as well as CO2 and N fertilization, and irrigation feedback effects. With the simulation of heat stress impact by canopy temperature, irrigation reduces soil water stress and cools canopy temperature, which in turn feedbacks the crop growth during the growing season and heat stress impact during the reproductive period. Over the 21st century, the adverse warmer temperature effect on corn and soybean yield is alleviated by other drivers, mainly the increase in atmospheric CO2 concentration and resultant changes in the phenological events due to climate change, particularly planting dates and harvesting times, by 2090s under both scenarios. The results from this part have implications for understanding the potential management adaptation of N fertilizer, planting time, and irrigation on future corn and soybean yield and their interactions with environmental factors, including climate and atmospheric CO2. Chapter 3 extends the framework developed in the first part to assess historical rice yield and production at 0.5-degree spatial resolution. I have implemented a rice growth module in ISAM, which accounts for flooded irrigation, transplanting, multiple seasons, and surface water layer processes. After evaluating the model processes using the site-level observations and global datasets, the model is applied to study the historical environmental and management factors on global rice production. The model results estimated global rice yield from transplanted rice is higher than from direct-seeded rice. Still, the rice production is higher from direct-seeded due to higher cultivated areas. Among the three rice growing seasons, rice harvested in the main growing season one features the longest growing period with favorable climate conditions, resulting in the highest yield and production. The global total production of rice for 2006-2015 is 713 million tons, with South and Southeast Asia by far the largest rice-producing region, and China (24%), India (22%), and Thailand (9%) being the top three producers. The expansion of total rice harvested areas is the major contributor (56%). Other positive effects of environmental and management factors on rice production include N fertilizer and manure (23%), N deposition (2%), and rising atmospheric CO2 concentration (24%). In contrast, climate change reduced production by 5%. Chapter 4 investigates the historical climate trend and extremes and management practices (i.e., seeding rate, N fertilizer, cultivar choice, irrigation, and area expansion) on corn yield and production in the United States at 0.1-degree spatial resolution. I implement a longer growing season cultivar into ISAM by modifying corn phenology using the observation data for a longer growing season cultivar. A longer-growing season corn cultivar indicates the reproductive period has been lengthened by approximately 0.21 days per year and has contributed to 27% of the observed increase in national corn production since 1980. The model simulations capture the corn productivity loss due to extreme climate events. Specifically, the model captures yield responses to heatwaves, droughts, and floods and explains the observed national corn yield and production annual variability by 69% and 82%, respectively. Without considering spatial variations in longer-growing cultivars, the explainable annual variability for corn yield and production are reduced from 69 to 56% and 82 to 64%, respectively. Chapter 5 extends the US scale model of Chapter 4 to assess the bioethanol yield from cultivating corn and bioenergy grasses, including Miscanthus, and two different cultivars of switchgrass, Cave-in-Rock, and Alamo in the Central and Eastern United States. Bioenergy grasses require more water than corn but improve water quality due to controlling nitrogen leaching relative to corn. Growing bioenergy grasses are also less affected by 2012 Midwest extreme droughts and heatwaves events than corn because bioenergy grasses are perennial with deeper and denser roots. Therefore relatively less impacted by water stress because deeper roots can extract the water from deeper moist soils. However, the high-yield region of bioenergy crops in the southern and eastern States of the Midwest are overlapped with the corn cultivated region, implying concerns about competition with food production. Chapter 6 extends the US scale land surface model developed and applied in Chapters 4 and 5 by coupling it with WRF (Weather Research and Forecasting) model. The coupled ISAM-WRF model investigates the feedback between changes in surface energy and water fluxes and atmospheric temperature and precipitations due to crop cultivars in the Midwest United States. I use ISAM-WRF to study the effects of the above-described longer-season cultivars on the surface climate variables including, temperature and precipitation and changes in these climate conditions on corn/soybean yields. Through the land-atmospheric coupling, the long-growing cultivars change the daily mean 2-m temperature between -1.5 and 1oC and precipitation between -10 and 10 mm per day during the growing season at a Bondville, IL, cropland flux site, highlighting the agricultural management on crops can increase productivity and change the seasonal climate. The modeled precipitation, near-surface temperature, and surface energy budgets are well evaluated with observational data and show that the results capture seasonal variability of regional climate, implying the importance of developing crop productivity in numerical weather prediction and climate models to study feedback processes. Chapter 7 provides the overall summary and suggestions for possible future work related to the study in the dissertation
Supplemental Material for Lin, Lin, and Lin, 2020
No full textFigure S1 shows 10 linkage groups on genetic map of the F2 population derived
from NH80-A
x TA95. Figure S2 shows 10 linkage groups on genetic
map of the BC1 population derived from NH80-A x WH606. Table S1 displays
predicted genotypes of each line under multi-allelic and two-gene
models, respectively. Tables S2, S3, and S4 display
segregation ratios of male sterility in progeny tests A, B, and C, respectively.
File S1 contains the physical positions of polymorphic tags and genotypic data
of F2 population derived from NH80-A × TA95. File S2 contains the
physical positions of polymorphic tags and genotypic data of BC1
population derived from NH80-A × WH606. File S3 contains four genomic DNA
sequences of BnRf orthologs.</p
Isolation and Characterization of a Hpyc1i Restriction-Modification System in Helicobacter Pylori
No full textUsing transposon shuttle mutagenesis, we identified six Helicobacter pylori mutants from the NTUH-C1 strain that exhibited decreased adherence and cell elongation. Inverse polymerase chain reaction and DNA sequencing revealed that the same locus was interrupted in these six mutants. Nucleotide and amino acid sequences showed no homologies with H. pylori 26695 and J99 strains. This novel open reading frame contained 1617 base pairs. The amino acid sequence shared 24% identity with a putative nicking enzyme in Bacillus halodurans and 23 and 20% identity with type IIS restriction endonucleases PleI and MlyI, respectively. The purified protein, HpyC1I, showed endonuclease activity with the recognition and cleavage site 5'-CCATC( 4/5)-3'. Two open reading frames were located upstream of the gene encoding HpyC1I. Together, HpyC1I and these two putative methyltransferases (M1.HpyC1I and M2.HpyC1I) function as a restriction-modification (R-M) system. The HpyC1I R-M genes were found in 9 of the 15 H. pylori strains tested. When compared with the full genome, significantly lower G C content of HpyC1I R-M genes implied that these genes might have been acquired by horizontal gene transfer. Plasmid DNA transformation efficiencies and chromosomal DNA digestion assays demonstrated protection from HpyC1I digestion by the R-M system. In conclusion, we have identified a novel R-M system present in similar to60% of H. pylori strains. Disruption of this R-M system results in cell elongation and susceptibility to HpyC1I digestion
Isolation and Characterization of a Competence Operon Associated with Transformation and Adhesion in Helicobacter Pylori
No full textTo identify adhesion-associated loci, we screened 1500 mutant strains of a Helicobacter pylori mutant library. A mutant that showed decreased adhesion to two gastric epithelial cell lines was identified. Inverse polymerase chain reaction (PCR) revealed that the interrupted locus of this mutant was an hp0015 homolog of H. pylori strain 26695. DNA sequencing and reverse-transcription PCR revealed that hp0015 and two downstream genes (hp0016 and hp0017) were a transcriptional unit. Deletion and complementation constructs revealed that hp0016 and hp0017 were involved in natural transformation, but not in adhesion. Hp0015 was associated with both adhesion and natural transformation. The reduction of adhesion to human gastric tissues in the hp 0015 mutant was similar to that of the babA2 knockout mutants and greater than that of the sabA knockout mutants. Co-culture of a wild-type strain with AGS cells revealed that 19 genes in AGS cells were upregulated; however, five of the 19 genes were not induced by co-culture with hp0015 mutants. These results indicate that hp0015 is associated with adhesion, and hp0015, hp0016, and hp0017 are associated with natural transformation. Hp0017 has been named as virB4 /comB4. Therefore, hp0015 and hp0016 are named as comB2 and comB3 , respectively. (c) 2006 Elsevier Masson SAS. All rights reserved
Cross-lingual Automatic Short Answer Grading System Based on Few-shot Learning
No full textThis study aims to address the grading challenges in the globalized education environment, developing a cross-linguistic automatic short answer grading system based on few-shot learning. The system is adaptive to new cross-linguistic short answer grading tasks under small sample conditions. The merits of short answer grading are its ability to better measure students' understanding and knowledge expression, yet it encounters the complexities of answer diversity, multi-language environment, and data annotation difficulties.
Our methodology mainly utilizes cross-linguistic transfer learning and twin neural networks, supplemented by external knowledge to enhance the model's representational power. Specifically, we calculate the differential features among answers and adjust the model weights accordingly to improve grading accuracy. In the experimental segment, we conduct experiments on multi-language datasets and compare them with existing grading methods.
The experimental results demonstrate that our cross-linguistic automatic short answer grading system achieves excellent prediction performance, even with few samples, and exhibits high grading accuracy and feasibility in multi-language environments. The system has robust generalization capabilities, effectively addressing the grading challenges in multi-language environments, providing a novel solution for educational assessment and automated testing domains. The development of this study pioneers the short answer grading direction in non-English languages, offering a new possibility for future educational assessment in multi-language environments
Application of Multiphoton Fluorescence and Second Harmonic Generation Microscopy in Diagnosing Hepatocellular Carcinoma
No full text肝癌長久以來一直是國人揮之不去夢魘，而國內對於肝癌的研究也是相當重視。但是醫師對於癌症判斷，卻僅止於經驗法則，雖然此法已行之有年，但主觀上判讀仍是存在精確度的疑慮。若有更客觀的方式，去建立一套分析的準則，不僅可以提高癌症級數判讀的準確度，同樣也是輔助醫師的一項利器。
而本實驗室便是利用雙光子螢光與二倍頻顯微術(以下簡稱顯微術)來觀測肝細胞癌(HCC)切片，藉此達到上述之目的。藉著本實驗室顯微術系統，掃描各級數是切片樣本，在擷取其螢光與二倍頻影像，再進一步分析。
將取得之影像對其雙光子螢光或是二倍頻訊號強度，與各種參數分析，試著去找出其中的對應關係與趨勢。而利用這些結果去建立一套較客觀的準則，藉此輔助或是精進癌症程度的判斷。
而目前所得結果顯示，就自發螢光而言，非癌症樣品較癌症樣品高，但仍需較多的樣本數來驗證。並試著藉此結論建立分級標準。Hepatic disease has always been a major health problem in Taiwan, with hepatocellular carcinoma (HCC) being among the leading causes of death. Since the diagnosis of the degree of liver carcinoma is done according to the doctor’s clinical experience, there is a need for a more objective determination of the extent of this cancer. In this work, we attempt to develop an objective method to help improve the accuracy of HCC classification which will be a useful aid for clinical investigations.
In this study, we make use of two-photon fluorescence (TPF) and second harmonic generation (SHG) microscopy in imaging hepatocellular carcinoma (HCC) specimens. By scanning thin sections of different HCC specimens, we attempt to correlate the change in the sample’s autofluorescence with parameters such as tumor size. We hope that this approach can lead to a more accurate classification of HCC.
Our preliminary results show that the autoflurescence intensity of non-tumor sample is higher than that of tumor sample. Our approach demonstrates the possibility of using tissue autofluroescence for tumor classification and the potential of this methodology for clinical diagnosis.Content
口試委員審定書 I
致謝 II
摘要 IV
Abstract V
Content VI
Figure Catalog VII
Chart Catalog VIII
Table Catalog VIII
Chapter 1 Introduction 1
Chapter2 Basic Principles 4
2.1 Second Harmonic Generation 4
2.2 Two-Photon Fluorescence 7
Chapter 3 Histology of Liver 13
3.1 Liver Structure and Function 13
3.2 Liver Circulation System 18
3.3 Cells of Liver 20
Chapter 4 Experimental Setup, Materials and Method 23
4.1 Experimental Setup 23
4.2 Experimental Materials 25
4.3 Method 26
Chapter 5 Results and Analysis 32
5.1 Introduction of TPF and SHG Imaging 32
5.2 Morphological Analysis 36
5.3 Autofluorescence Intensity Ratio Analysis 48
5.4 Optical Biopsy of Liver Fibrosis 49
Chapter 6 Conclusion 56
Reference 58
Figure Catalog
Fig.2.1.1 Second Harmonic Generation 5
Fig.2.2.1 Level k is spread into a density of states. 9
Fig.2.2.2 Two-Photon Fluorescence 11
Fig.2.2.3 Limited excitation volume of TPE 12
Fig.3.1.1 Liver anatomy 13
Fig.3.1.2 Structure of classical liver lobules 14
Fig.3.1.3 Three zones of liver acinus 15
Fig.3.1.4 The arrangement of hepatocytes and sinusoids 17
Fig.3.2.1 The circulation process of intrahepatic vascular system 18
Fig.3.2.2 The process of biliary circulation 19
Fig.3.3.1 The H&E stained paraffin fixation section of liver of B6 mou.e.. 21
Fig.4.1.1 Experimental setup 24
Fig.4.3.1 Multiphoton imaging of non-tumor specimens 28
Fig.4.3.2 Autofluorescence imaging of non-tumor specimens 28
Fig.4.3.3 Autofluorescence intensity inversion imaging 29
Fig.4.3.4 Nucleoli label 29
Fig.4.3.5 Result of nucleus counting 30
Fig.5.1.1 TPF and SHG microscopy imaging of non-tumor tissue (A), and histological comparison of non-tumor tissue (a). 33
Fig.5.1.2 TPF and SHG microscopy imaging of HCC tissue (A), and histological comparison (a). 34
Fig.5.1.3 Magnified view of selected areas in Fig.5.1.1 and Fig. 5.1.2 of TPF and SHG image and the corresponding histological section image. 35
Fig.5.2.1-1 TPF and SHG microscopy imaging of HCC grade1 (a), and histological comparison (b). 37
Fig.5.2.1-2 Magnified view of selected region in Fig.5.2.1-1. 38
Fig.5.2.2-1 (a) TPF and SHG imaging of HCC grade2, and (b) histological comparison. 39
Fig.5.2.2-2 Magnified view of selected regions in Fig.5.2.2-1. 40
Fig.5.2.3-1 (a) TPF and SHG microscopy imaging of HCC grade3, and (b) histological comparison. 41
Fig.5.2.3-2 Magnified view of selected regions of Fig. 5.2.3-1. 42
Fig.5.2.4-1 (a) TPF and SHG micrpscopy imaging of HCC grade4, and (b) histological comparison. 43
Fig.5.2.4-2 Magnified view selected regions of Fig. 5.2.4-1. 44
Fig.5.4.1 (a) TPF and SHG microscopy imaging of tissues with METAVIR grade0, and (b) the histological comparison. 50
Fig.5.4.2 (a) TPF and SHG microscopy imaging of tissues with METAVIR grade1, and (b) the histological comparisons. 51
Fig.5.4.3 (a) TPF and SHG microscopy imaging of tissues with METAVIR grade2, and (b) the histological comparisons. 52
Fig.5.4.4 TPF and SHG microscopy imaging of tissues with METAVIR grade3, and (b) the histological comparisons 53
Fig.5.4.5 (a) TPF and SHG microscopy imaging of tissues with METAVIR grade4, and (b) the histological comparisons. 54
Chart Catalog
Chart 4.3.1 Saturation test of non-tumor section 27
Chart 5.2.1 (a) The nuclear number per 100×100 μm2 area of non-tumor and tumor specimens for different grade of cancer. (b) The nuclear number per 100×100 μm2 area for non-tumor and tumor specimens 45
Chart 5.2.2 (a) NC ratio for different grades of cancer. (b) NC ratio for non-tumor and tumor specimens. 46
Chart 5.3.1 Autofluorescence intensity ratio for different grades of cancer. 48
Table Catalog
Table 4.3.1 Saturation test of non-tumor section 26
Table 5.4.1 METAVIR grading system 4
The development of a regression model to predict sea temperature variations - A case of Peng Hu
No full textPeng Hu is located at the center of Taiwan Strait. The ecosystem and aquaculture here is plentiful, because of being effected by China Coast Current, South China Sea Current and branch of Kuroshio. Above these, Peng Hu becomes an important fishery area in Taiwan.
In 2008 and 2011, cold disaster happened around the sea area of Peng Hu, and resulted in a lot of fish died. Furthermore, marine ecosystem was destroyed and the fishery catch was reducing. In order to preventing the low sea temperature to make these kind of disaster, the technique of sea temperature forecasting is important and must develop to apply around Taiwan sea area.
In this study, we use multiple regression model to build sea surface temperature forecasting model. The model is trained by the observations in 2011 to predict the two-days-after sea surface temperature. The observations include sea surface temperature, air temperature, wind speed and cloud-cover-rate from Peng Hu and nearby Peng Hu atmosphere stations. After that, the model is validated by the data in 2008, 2015, 2017 and 2018. The result has a well-done and similar trend between the model and observation. The RMSE is about 0.4 and the relation coefficient is above 0.9. In conclusion, the Peng Hu multiple regression model is reliable
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