8,298 research outputs found
Fritz Allhoff and Patrick Lin, Eds. Nanotechnology and Society: Current and Emerging Ethical Issues
Get PDFNanotechnology & Society is the second anthology published by The Nanoethics Group (www.nanoethics.org) and is a welcome addition to the emerging field of nanoethics. Editors Fritz Allhoff (Western Michigan University) and Patrick Lin (California Polytechnic State) are among the leading philosophers in nanoethics and founders of The Nanoethics Group. While their first anthology, Nanoethics: The Ethical and Social Implications of Nanotechnology (2007, with editors James Moor and John Weckert), presented a general introduction to critical issues in nanoethics, in this new book Allhoff and Lin recognize nanotechnology’s “strange schizophrenia”—as a brave new science filled with unlimited futuristic vision contrasted with the exaggerated hype of research progress—and strive to foster a solid foundation for nanoethics (p. xxi)
Zinc has insulin-mimetic properties which enhance spinal fusion in a rat model
No full textBACKGROUND CONTEXT: Previous studies have found that insulin or insulin-like growth factor treatment can stimulate fracture healing in diabetic and normal animal models, and increase fusion rates in a rat spinal fusion model. Insulin-mimetic agents, such as zinc, have demonstrated antidiabetic effects in animal and human studies, and these agents that mimic the effects of insulin could produce the same beneficial effects on bone regeneration and spinal fusion.
PURPOSE: The purpose of this study was to analyze the effects of locally applied zinc on spinal fusion in a rat model.
STUDY DESIGN/SETTING: Institutional Animal Care and Use Committee-approved animal study using Sprague-Dawley rats was used as the study design.
METHODS: Thirty Sprague-Dawley rats (450-500 g) underwent L4-L5 posterolateral lumbar fusion (PLF). After decortication and application of approximately 0.3 g of autograft per side, one of three pellets were added to each site: high-dose zinc calcium sulfate (ZnCaSO4), low-dose ZnCaSO4 (half of the high dose), or a control palmitic acid pellet (no Zn dose). Systemic blood glucose levels were measured 24 hours postoperatively. Rats were sacrificed after 8 weeks and the PLFs analyzed qualitatively by manual palpation and radiograph review, and quantitatively by micro-computed tomography (CT) analysis of bone volume and trabecular thickness. Statistical analyses with p-values set at .05 were accomplished with analysis of variance, followed by posthoc tests for quantitative data, or Mann-Whitney rank tests for qualitative assessments.
RESULTS: Compared with controls, the low-dose zinc group demonstrated a significantly higher manual palpation grade (p=.011), radiographic score (p=.045), and bone formation on micro-CT (172.9 mm3 vs. 126.7 mm3 for controls) (p3 vs. 126.7 mm3) (p<.01) versus controls, and was trending toward higher manual palpation scores (p=.058).
CONCLUSIONS: This study demonstrates the potential benefit of a locally applied insulin-mimetic agent, such as zinc, in a rat lumbar fusion model. Previous studies have demonstrated the benefits of local insulin application in the same model, and it appears that zinc has similar effects.Peer reviewe
Harmonies of political economy / by Frédéric Bastiat ; translated from the French, with a notice of the life and writings of the author, by Patrick James Stirling
No full textTranslation of the first 10 chapters of "Harmonies économiques"Advertisement on p. [299]Bastiat, Frédéric, 1801-1850Stirling, Patrick James, 1809-1891Physical description: xl, 298, [1] p. ; 23 cmLocation of original: Center for Historical Social Science Literature, Hitotsubashi University -- Call no. : Franklin:91Technical requirements: DjVu plugin is required to read text
The poetical works of Patrick Hannay, A.M. MDCXXII : with a memoir of the author.
No full text"A faithful and literal re-publication" of the rare 1622 edition of Hannay's collected poems. With facsimile of original engraved t.-p.: The Nightingale. Sheretine and Mariana. A happy husband. Eligies on the death of Queene Anne. Songs and Sonnets by Patrick Hanay gent. London printed for Nathaniel Butler. 1622."Memoir of Patrick Hannay, A.M., by David Laing...": p. 7-47."Presented to the members of the Hunterian club by Thomas Russell."Philomela, the nightingale.--Sheretine and Mariana.--A happy husband: or, Directions for a maid to chvse her mate. Together with A wives behaviovr after mariage. The second edition.--Elegies, on the death of ovr late soueraigne Qveene Anne. With epitaphs.--Songs and sonnets.Mode of access: Internet
Supplemental Material - Chronic Non-cancer Pain and Associated Risks of Incident Mild Cognitive Impairment and Alzheimer’s Disease and Related Dementias in Middle-Aged and Older Adults
No full textSupplemental Material for Chronic Non-cancer Pain and Associated Risks of Incident Mild Cognitive Impairment and Alzheimer’s Disease and Related Dementias in Middle-Aged and Older Adults by Yi-Han Hu, Dong-Chul Seo, Lesa Huber, Patrick C. Shih, and Hsien-Chang Lin in Journal of Applied Gerontology.</p
Measuring industry-science links through inventor-author relations: A profiling method
Get PDFIn this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;
sj-docx-1-psg-10.1177_22925503231184266 - Supplemental material for A Systematic Review of the Reporting Quality of Qualitative Research in Breast Plastic Surgery
No full textSupplemental material, sj-docx-1-psg-10.1177_22925503231184266 for A Systematic Review of the Reporting Quality of Qualitative Research in Breast Plastic Surgery by Caroline Hircock, Cameron F Leveille, Jeffrey Chen, Xue-Wei Lin, Rafael P Lansang, Patrick J Kim, Peter W Huan, Lucas Gallo and Achilles Thoma in Plastic Surgery</p
sj-xlsx-2-psg-10.1177_22925503231184266 - Supplemental material for A Systematic Review of the Reporting Quality of Qualitative Research in Breast Plastic Surgery
No full textSupplemental material, sj-xlsx-2-psg-10.1177_22925503231184266 for A Systematic Review of the Reporting Quality of Qualitative Research in Breast Plastic Surgery by Caroline Hircock, Cameron F Leveille, Jeffrey Chen, Xue-Wei Lin, Rafael P Lansang, Patrick J Kim, Peter W Huan, Lucas Gallo and Achilles Thoma in Plastic Surgery</p
sj-docx-3-psg-10.1177_22925503231184266 - Supplemental material for A Systematic Review of the Reporting Quality of Qualitative Research in Breast Plastic Surgery
No full textSupplemental material, sj-docx-3-psg-10.1177_22925503231184266 for A Systematic Review of the Reporting Quality of Qualitative Research in Breast Plastic Surgery by Caroline Hircock, Cameron F Leveille, Jeffrey Chen, Xue-Wei Lin, Rafael P Lansang, Patrick J Kim, Peter W Huan, Lucas Gallo and Achilles Thoma in Plastic Surgery</p
An historical account of the life and reign of David King of Israel. [electronic resource] : In four books. ... In which ... Mr. Bayle's criticisms, ... are fully considered. By the author of Revelation examined with candour. In two volumes.
No full textThe author of 'Revelation examined with candor' = Patrick Delaney.Vol.2 includes 'Reflections upon the present neglect of the public worship of God'.Electronic reproduction.English Short Title Catalog,Reproduction of original from British Library
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