1,720,960 research outputs found
Development of High-intensity Focused Ultrasound Thermal Surgery System with Ultrasound Imaging Guidance and Temperature Feedback
本研究開發了搭配超音波影像與熱電偶溫度量測之聚焦式超音波熱手術系統,利用油壓缸與電腦控制伺服馬達將聚焦超音波換能器移動至目標區並由防水光學尺量測實際移動距離。熱手術系統將自動定位系統、聚焦超音波換能器、電功率放大器、超音波影像系統、熱電偶溫度量測系統整合至圖形化使用者介面。而熱手術治療流程包含利用由診斷用超因波波束與聚焦超音波波束所形成的聲干擾作為聚焦超音波焦點的影像導引,並將兩根熱電偶透過超音波影像導入蛋白仿體與豬肉組織體,用來量測溫度治療區溫度來監控受測體治療過程。而為了達到多點治療的目的,聚焦超音波換能器利用聲干擾焦點定位法導引移動至其他欲治療區並使用相同電功率和時間作治療。初步的蛋白仿體與豬肉組織實驗結果證明此熱手術系統能有效地完成所規劃的治療策略。In this study, we developed a focused ultrasound (FUS) thermal therapy system with B-mode ultrasound image guidance and thermocouple temperature measurement feedback. Hydraulic position devices and computer-controlled servo motors were used to move the FUS transducer to the desired location with the measurement of actual movement by linear scale. The entire system integrated automatic position devices, FUS transducer, power amplifier, ultrasound image system, and thermocouple temperature measurement system into a graphical user interface. For the treatment procedure, thermocouples were implanted into a targeted treatment region in a tissue-mimicking phantom or pork tissue under ultrasound image guidance and then the acoustic interference pattern formed by image ultrasound beam and high-power FUS beam was employed as image guidance, to move the FUS transducer to the desired treatment region The measurement of temperature was used to monitor the status of sonication duration. For a multiple lesion formation, the FUS transducer was moved under the acoustic interference guidance to a new location and then it sonicated with the same power level and duration. The preliminary phantom and pork tissue experimental results demonstrated that the system could achieve the desired treatment plan effectively.誌謝 I要 IIbstract III錄 IV目錄 VI目錄 VII一章 緒論 1.1. 引言 1.2 超音波與生物物質相互作用的基本原理 1.2.1 機械效應 2.2.2 熱效應 2.2.3 空蝕化效應 2.2.4 溫度與熱劑量分析 3.3 超音波熱治療 4.4 超音波熱治療發展與應用 5.5 超音波熱治療系統概觀 6.6 研究動機與目的 9二章 超音波熱手術系統開發與製作 12.1 超音波熱手術系統組成 12.2 機構致動元件 13.3 防水光學尺位移量測 14.4 聲干擾焦點定位法 14.5 系統介面整合 15.5.1 高強度聚焦超音波介面 15.5.2 診斷用超音波影像與治療規劃介面 15.5.3 伺服馬達控制介面 16.5.4 熱電偶溫度量測介面 16.6 超音波熱手術系統架構 17.7 熱手術系統操作流程 18三章 實驗與材料方法 31.1. 實驗設備 31.1.1 高強度聚焦超音波和匹配電路 31.1.2 四頻道功率放大器 31.1.3 診斷用影像超音波 32.1.4 溫度量測儀 32.2 實驗材料 33.2.1 去氣水 33.2.2 蛋白仿體 33.2.3 豬肉組織體 34.3 熱手術系統測試實驗 35.3.1 燒灼焦斑直徑與位置在診斷用超音波影像與實際影像差異實驗 35.3.2 由診斷用超音波影像規劃熱手術 36.3.3 聲干擾焦點定位法與實際焦點位置誤差實驗 36.3.4 藉由聲干擾焦點定位法規劃並監控熱手術與溫度回授控制 37四章 系統測試與實驗結果 45.1 燒灼焦斑在診斷用超音波影像與CCD影像差異實驗 45.2 由診斷用超音波影像規劃熱手術 45.3 聲干擾焦點定位法與實際焦點位置誤差實驗 45.4 藉由聲干擾焦點定位法規劃並監控熱手術與溫度回授控制 46五章 討論 57六章 結論與未來展望 59考文獻 6
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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