552 research outputs found
Supplement_Figure_1 - The Neuroprotective Effects of Necrostatin-1 on Subarachnoid Hemorrhage in Rats are Possibly Mediated by Preventing Blood–Brain Barrier Disruption and RIP3-Mediated Necroptosis
Supplement_Figure_1 for The Neuroprotective Effects of Necrostatin-1 on Subarachnoid Hemorrhage in Rats are Possibly Mediated by Preventing Blood–Brain Barrier Disruption and RIP3-Mediated Necroptosis by Jingsen Chen, Hanghuang Jin, Hangzhe Xu, Yucong Peng, Liyong Jie, Demin Xu, Lili Chen, Tao Li, Linfeng Fan, Pingyou He, Guangyu Ying, Chi Gu, Chun Wang, Lin Wang and Gao Chen in Cell Transplantation</p
Recommended from our members
Trust filter for disease surveillance : Identity
A flexible and extensible mobile application was delivered for evaluation and optimal inclusion of NextGen (Next Generation) data sources into biosurveillance for early detection, situational awareness and prediction. We present trust analysis of NextGen data sources to increase data confidence. One of the trust filters is the Identity filter, which helps us determine the degree of separation between the sender and the subject of a sentence. In this thesis, the author presents the definition of Identity. To help us distinguish different degrees of separation, the author uses relation distance along with a family tree to weight different relationships. Then the author compares a discriminative algorithm and a generative algorithm to calculate a user's Identity score. In the end, the author concludes that it is a good choice to apply a binary classification algorithm combined with a Natural Language Processing algorithm because of the trade-off between accuracy and runtime complexity.Electrical and Computer Engineerin
Recommended from our members
Modeling Oil Spilling On Water
For the offshore oil industry, a primary concern is an accidental oil spill. Potentially, oil can spill from the platform during the extraction or from the tanker during the transportation, in both cases will flow into the nearby sea. After an oil spill occurs, to prevent it from polluting even more areas and recover the polluted area, scientists want to understand the process of oil spreading on the sea.
In this dissertation, we study the phenomena of oil spreading on water surface. We address a reduced model that captures the local dynamics of an oil slick spreading on flowing water surface and provides an insight on the trend of the spreading process. When the underlying water is locally steady, a full PDE model is analyzed to yield the velocity of the oil slick and its spreading rate. For spreading on a water surface where the flow is locally contracting towards the center of the oil slick, a stationary state is found for the oil slick. For an oil slick spreading on a water surface where the flow is locally expanding towards the edge the slick, the asymptotic spreading rate of the slick and a quasi-steady state are found in this case. We also develop numerical schemes that simulate the dynamics of an oil slick spreading on steady water surface and surface with expanding water flow.
For modeling the evolution of crude oil, we introduce a dimension reduction for systems with slow relaxation and develop a multilayer stochastic model. Using the multilayer reduced model, we are able to estimate a single observable quantity of oil based on its past states, without further knowledge on the 'microscopic structure' inside the crude oil. Through synthetic data experiments, our reduced model is demonstrated to have an improved accuracy when implemented with data assimilation methods and can maintain stability while predicting a future state when no data is available
On New Media Art, Its Development and Achievement in China
This essay is aimed to introduce the development status of the new media art in China; the author gave its definition based on his own understanding and observation, which included various forms. Moreover, the developing environment of the new media art in the world is presented systematically in the essay. The author combed the art history and technology history which are closely connected with the birth of the new media art. China has achieved many accomplishments in new media art forms, such as the successful hosting of 2008 World Olympic Games and 2010 World expo. In the opening ceremony of 2008 World Olympic Games, interactive art, installation art and virtual space are in perfect use. Especially, “scroll” has combined all the above technological methods into display, which brought about stunning sensory impact to the audiences. After two years, Shanghai was the focus of the world, 242 countries and international organizations that have attended 2010 Shanghai World expo. The new media art forms are bloomed and flourished, China pavilion’s Qingming Riverside was endowed with new vitality via these new art media forms
The correlation between renal function and arterial elasticity function in essential hypertensive patients
Correlation and impact factors between pulse wave velocity and indexes of arterial elasticity function on different sites of arterial system in hypertensive patients
China’s Stances toward International Norms Viewed through the Belt and Road Initiative
The development of China, its increasing international influence, and the shift from a low foreign policy profile to a more proactive, assertive, and coercive one have renewed the debate on China’s stance toward international norms. This chapter introduces the book’s approach to analyzing China’s relationship to international norms and the extent to which the Belt and Road Initiative (BRI) affects norm conformity behavior. Existing paradigms suggest that international norms and standards influence how states behave in the international arena and that states try to influence those norms and standards according to their interests and values. Building on existing literature that analyzes states’ relationship with international norms, the chapter presents a conceptual framework with five categories (cooperation, compliance, qualification, infraction, and subversion) that broadens binary models of compliance versus non-compliance. The analysis is also: diachronic, to capture the variations of China’s level of compliance and influence on international norms; qualitative, to address the complexity of international regimes, state’s interactions with them, and subsequent endogeneity issues; multi-level, taking into consideration the role of sub-state Chinese stakeholders; and cross-sectorial, through seven case studies that address some of the key issues on the international agenda. It gathers empirical evidence from the BRI, highlighting its economic, strategic, and normative implications. This conceptual framework allows for complex and nuanced analyses, which acknowledge that a state’s relationship with international norms is dynamic and varies depending on the regime studied.</p
Quantitative observations of a deep-sea hydrothermal plume using an acoustic imaging sonar
The Cabled Observatory Vent Imaging Sonar (COVIS) is used to quantitatively monitor the hydrothermal discharge from the Grotto mound, a venting sulfide structure on the Endeavour Segment of the Juan de Fuca Ridge. Since its deployment in September 2010, COVIS has recorded a multi-year long, near-continuous acoustic backscatter dataset. Further analysis of this dataset sheds light on the backscattering mechanisms within the buoyant plumes above Grotto and yields quantitative information on the influences of oceanic, atmospheric, and geological processes on the dynamics and heat source of the plumes. An investigation of the acoustic scattering mechanisms within the buoyant plumes issuing from Grotto suggests the dominant scattering mechanism within the plumes is the temperature fluctuations caused by the turbulent mixing of the buoyant plumes with the ambient seawater. In comparison, the backscatter from plume particles is negligible at lower levels of the plume but can potentially be signi cant at higher levels. Furthermore, this finding demonstrates the potential of inverting the acoustic backsatter to estimate the temperature fluctuations within the plumes. Processing the backscatter dataset recorded by COVIS yields time-series measurements of the vertical flow rate, volume transport, expansion rate of the largest buoyant plume above Grotto. Further analysis of those time-series measurements suggests the rate at which the ambient seawater is entrained into the plume increases with the magnitude of the ambient ocean currents---the current-driven entrainment. Furthermore, the oscillations in the ambient ocean currents that are driven by tidal and atmospheric forcing are introduced into the flow field within the plume through the current-driven entrainment. An inverse method has been developed to estimate the source heat transport driving the largest plume above Grotto from its volume transport estimates. The result suggests the heat transport driving the plume was steady over the 41-month period between October 2011 and February 2015. Comparing the current and historical heat transport measurements with contemporaneous seismic data suggests the evolution of the heat transport since 1988 correlates with the rate of local seismicity with a short episode of increased heat transport following pronounced seismic events and reduced steady heat transport during time periods of quiescent seismicity.Ph.D.Includes bibliographical referencesby Guangyu X
Bivariate joint analysis of injury severity of drivers in truck-car crashes accommodating multilayer unobserved heterogeneity
Truck-involved crashes, especially truck-car crashes, are associated with serious and even fatal injuries, thus necessitating an in-depth analysis. Prior research focused solely on examining the injury severity of truck drivers or developed separate performance models for truck and car drivers. However, the severity of injuries to both drivers in the same truck-car crash may be interrelated, and influencing factors of injury severities sustained by the two parties may differ. To address these concerns, a random parameter bivariate probit model with heterogeneity in means (RPBPHM) is applied to examine factors affecting the injury severity of both drivers in the same truck-car crash and how these factors change over the years. Using truck-car crash data from 2017 to 2019 in the UK, the dependent variable is defined as slight injury and serious injury or fatality. Factors such as driver, vehicle, road, and environmental characteristics are statistically analyzed in this study. According to the findings, the RPBPHM model demonstrated a remarkable statistical fit, and a positive correlation was observed between the two drivers' injury severity in truck-car crashes. More importantly, the effects of the explanatory factors showing relatively temporal stability vary across different types of vehicle crashes. For example, car driver improper actions and lane changing by trucks, have a significant interactive effect on the severity of injuries sustained by drivers involved collisions between trucks and cars. Male truck drivers, young truck drivers, older truck drivers, and truck drivers' improper actions, elevate the estimated odds of only truck drivers; while older car and unsignalized crossing increase the possibility of injury severity of only car drivers. Finally, due to shared unobserved crash-specific factors, the 30-mph speed limit, dark no lights, and head-on collision, significantly affect the severity of injuries sustained by drivers involved in collisions between trucks and cars. The modeling approach provides a novel framework for jointly analyzing truck-involved crash injury severities. The findings will help policymakers take the necessary actions to reduce truck-car crashes by implementing appropriate and accurate safety countermeasures.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Transport and Plannin
- …
