93,726 research outputs found

    LIN-39 promotes neuronal fate specification in the Q and V5 lineage.

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    (A) The expression of lin-39 in AVM, SDQL/R, PDEL/R, and PVDL/R, indicated by the overlapping with neurotransmitter identity markers and specific fate markers (uIs115[mec-17p::TagRFP] for AVM, otIs181[dat-1p::mCh] for PDE, uIs117[lad-2p::mCh] for SDQ). (B) The expression of mab-5 in SDQL. (C) Summary of lin-39 (green) and mab-5 (cyan) expression in the descendants of Q and V5 lineages. (D) The loss of gcy-37 expression in AQR and AVM neurons in lin-39(n1760) mutants and the mispositioning of PQR in mab-5(gk670) mutants; the loss of lad-2 expression in SDQR in lin-39(n1760) mutants, the displacement of SDQL in mab-5(gk670) mutants, and the loss of lad-2 expression in both SDQs in lin-39(n1760) mab-5(e1239) mutants. The right panels show the penetrance for the loss of marker expression and cell body mispositioning. Mean ± SD for the percentage of cells showing corresponding phenotypes from three biological replicates are shown. Double asterisks indicate statistically significant difference (p Chi-square test. (E) The loss of ser-2 expression in PVD and PDE neurons and the loss of F49H12.4 expression in PVD in lin-39(n1760) and ceh-20(u843) mutants. (F) Dopaminergic marker dat-1 is normally expressed in PDE neurons in lin-39 mutants, but PDE shows axonal growth defects. The arrows indicate the termini of PDE axons. The expression of glutamatergic identity marker eat-4 and the PVD terminal selector gene mec-3 in PVD neurons in lin-39 mutants.</p

    Review of Mayer, R.; Knothe, F.; Shuo, H. (2022) Reflected beauty: Chinese reverse glass paintings from the Mei Lin Collection

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    In this well-documented, bilingual, and richly illustrated catalogue, published for the long-anticipated exhibition Reflected Beauty: Chinese Reverse Glass Paintings from the Mei Lin Collection at the University Museum and Art Gallery of the University of Hong Kong (September 2021-January 2022), the authors give us a profound insight into the phenomenon of reverse painting on glass and mirror paintings, with a particular focus on those from the Mei Lin Collection assembled by the Sinologist, author, and translator Rupprecht Mayer and his wife Haitang Mayer-Liem. Composed of over one hundred works acquired in East Asia between 1968 and 2012, this is one of the world's most important collections of Chinese reverse glass paintings from the late nineteenth and twentieth centuries.Modern and Contemporary Studie

    The Biased Homogeneous r-Lin Problem

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    The p-biased Homogeneous r-Lin problem (Hom-r-Lin_p) is the following: given a homogeneous system of r-variable equations over m{F}₂, the goal is to find an assignment of relative weight p that satisfies the maximum number of equations. In a celebrated work, Håstad (JACM 2001) showed that the unconstrained variant of this i.e., Max-3-Lin, is hard to approximate beyond a factor of 1/2. This is also tight due to the naive random guessing algorithm which sets every variable uniformly from {0,1}. Subsequently, Holmerin and Khot (STOC 2004) showed that the same holds for the balanced Hom-r-Lin problem as well. In this work, we explore the approximability of the Hom-r-Lin_p problem beyond the balanced setting (i.e., p ≠ 1/2), and investigate whether the (p-biased) random guessing algorithm is optimal for every p. Our results include the following: - The Hom-r-Lin_p problem has no efficient 1/2 + 1/2 (1 - 2p)^{r-2} + ε-approximation algorithm for every p if r is even, and for p ∈ (0,1/2] if r is odd, unless NP ⊂ ∪_{ε>0}DTIME(2^{n^ε}). - For any r and any p, there exists an efficient 1/2 (1 - e^{-2})-approximation algorithm for Hom-r-Lin_p. We show that this is also tight for odd values of r (up to o_r(1)-additive factors) assuming the Unique Games Conjecture. Our results imply that when r is even, then for large values of r, random guessing is near optimal for every p. On the other hand, when r is odd, our results illustrate an interesting contrast between the regimes p ∈ (0,1/2) (where random guessing is near optimal) and p → 1 (where random guessing is far from optimal). A key technical contribution of our work is a generalization of Håstad’s 3-query dictatorship test to the p-biased setting

    Observational Constraints on the f(R) Theory of Modified Gravity

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    我們利用宇宙學以及局部尺度的實驗去制約f(R) 設計者模型(designer f(R) models)。對於宇宙學尺度的制約,我們發現,儘管可以產生任何期望的宇宙膨脹,然而為了要符合大尺度結構實驗的制約,f(R)設計者遭受到微調問題 (fine-tuning problem)。對於局部重力的制約,目前為止,我們找到了通過局部重力測試的f(R)設計者模型;但是對於這些模型,甚至考慮宇宙學以及局部尺度也無法將它們從宇宙常數模型(ΛCDM model)分辨出來。對於其它在這篇碩士論文所考慮的有效狀態方程,我們未找到可通過局部重力測試的f(R)設計者模型。In this thesis we constrain the designer f(R) models by the observations in both cosmological and local scales. For the cosmological observation constraints, we find that although the designer f(R) can generate any desired cosmic expansion his-tory, it suffers from the fine-tuning problem in order to fit the large scale structure constraints well. For local gravity constraints, so far we do search out the viable designer f(R) models that can satisfy the local gravity constraints but would be indistinguishable from the ΛCDM model even considering the observations in both cosmological and local scales and for other effective equation of states we consider in this thesis, we do not find out any viable designer f(R) model

    Lysmata bahia Rhyne & Lin 2006

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    Lysmata bahia Rhyne & Lin, 2006 (Figure 7F) Material examined. Penaeid—1 OF; CL: 9.4 mm; CZUFS CRU- 00317. Stations. Penaeid—4. Distribution. Western Atlantic—Panama (Bocas Del Toro), and Brazil (Ceará, Sergipe, Bahia, Rio de Janeiro, and São Paulo) (Rhyne & Lin 2006; Baeza 2008; Barros-Alves et al. 2015; Pachelle et al. 2016). Ecological notes. Found at 5 m depth, on non-consolidated bottoms, on reefs, and inside calcareous algae (Almeida et al. 2012). Remarks. Part of a monophyletic group composed of Lysmata gacilirostris Wicksten, L. pederseni Rhyne & Lin, L. ankeri Rhyne & Lin, L. nayaritensis Wiksten, L. californica (Stimpson), and L. bahia supported by phylogenetic analysis (Baeza 2010). Previous records in Sergipe. Barros-Alves et al. (2015).Published as part of Mendonça, Luana M. C., Guimarães, Carmen R. P., Santos, Rafael C., Alves, Douglas F. R., Barros-Alves, Samara P., Silva, Sonja L. R. & Hirose, Gustavo L., 2019, Decapod crustaceans from the continental shelf of Sergipe, northeastern Brazil, pp. 301-344 in Zootaxa 4712 (3) on page 330, DOI: 10.11646/zootaxa.4712.3.1, http://zenodo.org/record/358631

    Letter from Carl Hayden to F. R. Goodman, County Engineer

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    Letter from Carl Hayden to F. R. Goodman regarding the construction of new roads

    Letter from Carl Hayden to F. R. Goodman

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    Letter from Carl T. Hayden to F. R. Goodman concerning the purchase of Bright Angel Trail and construction of an approach road to the park

    Letter from F. R. Goodman to Carl Hayden

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    Letter from F. R. Goodman to Carl T. Hayden asking for clarification about the agreement to construct an approach road to the par

    Raabeina longhiensis Lin & Zhang 2019, sp. nov.

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    Raabeina longhiensis Lin & Zhang sp. nov. (Figs. 1, 2, 3) Description. Head slightly narrower than pronotum, crown with anterior margin subparallel to posterior margin, coronal suture distinct (Figs. 1a, c, e, g). Face with frontoclypeus and anteclypeus narrow (Figs. 1d, h). Eyes grey, somewhat black (Fig. 1). Face pale yellow (Figs. 1d, h). Vertex and streak along coronal suture orange and formed two pairs of patches in different sizes with light color (Figs. 1a, c, e, g). Patches on hind angles of pronotum and apex of scutellum, black; orange umbrella framework pattern across pronotum, scutum and scutellum yellow, somewhat orange, triangles yellow (Figs. 1a, c, e, g). Fore wings pale, semitransparent (Figs. 1a, b, e, f). Ground color of abdominal tergites yellow to orange, with transverse stripes on each tergite, black (Figs. 1a, b, e, f). Abdominal apodemes reaching middle of fifth sternite or nearly reaching sixth sternite (Fig. 3b). Anal tube appendage arcuate or with obvious right-angle bend medially, extending far beyond pygofer hind margin (Figs. 2a, b; 3g, h). Pygofer side with three to five macrosetae at lower basal angle and row of nine to ten rigid setae at hind margin (Figs. 2a, b). Subgenital plate with exceedingly long and well pigmented at distal region of apex; with three macrosetae at transitional part; without minute peg-like microsetae at the angle of caudal part; narrowed area short (Figs. 2a, b; 3a). Paramere apical part elongated with two dentate processes medially distinct or not, well bent (Figs. 3e, f). Aedeagal shaft broad, straight, as long as or shorter than preatrium (Figs. 3i, j). Small bifurcated process at apex of aedeagus in caudal view (Fig. 3k). Measurement. Length of male 4.1-4.4mm (including wing). Material examined. Holotype: &male;, CHINA, Guangxi Prov., Youjiang, Longhe, at lamp, 27 June 2018, coll. Shuanghu Lin; Paratypes: 12&male;&male;, same data as holotype; &male;, CHINA, Guangxi Prov., Youjiang, Longhe, at lamp, 28 June 2018, coll. Shuanghu Lin. Deposition. Entomological Museum, Northwest A&F University, Yangling, China. Remarks. This new species is extremely similar to R. curtihamata but can be distinguished by the shorter aedeagal shaft, the anal tube appendage extending far beyond pygofer hind margin, eyes grey, somewhat black, face with frontoclypeus and anteclypeus narrow, and centre of frontoclypeus without dark apically. Etymology. This new species is named after its type locality “Longhe”.Published as part of Lin, Shuanghu & Zhang, Yalin, 2019, Taxonomic study of the leafhopper genus Raabeina Dworakowska (Hemiptera Cicadellidae: Typhlocybinae: Erythroneurini), with description of a new species from China, pp. 171-176 in Zootaxa 4691 (2) on pages 172-176, DOI: 10.11646/zootaxa.4691.2.6, http://zenodo.org/record/352717
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