12,467 research outputs found
Father Andrew Mullen 1790-1818: a study in early nineteenth century spirituality
No full textThis thesis is laid out in three parts: Part I. The life and death of Andrew Mullen. The life is based, to a large extent, on a long letter to his mother, Catherine Mullen, dated 7 January 1810. The letter gives a definite insight into his spirituality based on his membership of the Archconfraternity of the Blessed Sacrament. There is a hint that he had a premonition of an early death. Part II. The burial of Andrew Mullen and the immediate cult to him This is based on documentary evidence. Part III. Most of this part is a catalogue of testimonies taken from 1993 onwards. Then there is the conclusion on the popular devotion to Andrew Mullen stressing the theological aspect of the subject. In the course of writing the thesis it was decided to separate the documentary evidence from the oral tradition. This was advantageous in developing the thesis, and the documents provided a secure basis for the oral tradition. Two pieces of information were found in March 1997. They are death notices: 2 January 1819, The Leinster Journal and 7 January 1819, The Car low Morning Post. There is a slight discrepancy between the two on the date of his death. Also this discrepancy shows a slight difference from the date of the tombstone
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
sel-11 and cdc-42, two negative modulators of LIN-12/Notch activity in C. elegans.
No full textLIN-12/Notch signaling is important for cell-cell interactions during development, and mutations resulting in constitutive LIN-12/Notch signaling can cause cancer. Loss of negative regulators of lin-12/Notch activity has the potential for influencing cell fate decisions during development and the genesis or aggressiveness of cancer.We describe two negative modulators of lin-12 activity in C. elegans. One gene, sel-11, was initially defined as a suppressor of a lin-12 hypomorphic allele; the other gene, cdc-42, is a well-studied Rho GTPase. Here, we show that SEL-11 corresponds to yeast Hrd1p and mammalian Synoviolin. We also show that cdc-42 has the genetic properties consistent with negative regulation of lin-12 activity during vulval precursor cell fate specification.Our results underscore the multiplicity of negative regulatory mechanisms that impact on lin-12/Notch activity and suggest novel mechanisms by which constitutive lin-12/Notch activity might be exacerbated in cancer
Effective shear speed in two-dimensional phononic crystals
No full textThe quasistatic limit of the antiplane shear-wave speed ('effective speed') c in 2D periodic lattices is studied. Two new closed-form estimates of c are derived by employing two different analytical approaches. The first proceeds from a standard background of the plane wave expansion (PWE). The second is a new approach, which resides in x-space and centers on the monodromy matrix (MM) introduced in the 2D case as the multiplicative integral, taken in one coordinate, of a matrix with components being the operators with respect to the other coordinate. On the numerical side, an efficient PWE-based scheme for computing c is proposed and implemented. The analytical and numerical findings are applied to several examples of 2D square lattices with two and three high contrast components, for which the new PWE and MM estimates are compared with the numerical data and with some known approximations. It is demonstrated that the PWE estimate is most efficient in the case of densely packed stiff inclusions, especially when they form a symmetric lattice, while in general it is the MM estimate that provides the best overall fitting accuracy.Peer reviewe
Expression and Androgen Regulation of C-Cam Cell Adhesion Molecule Isoforms in Rat Dorsal and Ventral Prostate
No full textC-CAM is an epithelial cell adhesion molecule with two major splice variants that differ in the length of the cytoplasmic domain. C-CAM1 (long (L)-form) strongly suppresses the tumorigenicity of human prostate carcinoma cells. In contrast, C-CAM2 (short (S)-form) does not exhibit tumor-suppressive activity. In the present study we have investigated the functional significance of L-form and S- form C-CAM in rat prostate by examining their expression and distribution in different prostate lobes and their response to androgen deprivation. RNase protection assays with a probe for both C-CAM isoforms detected high levels of C-CAM messages in the rat dorso-lateral prostate (DLP). L- and S- form proteins, localized by indirect immunofluorescence using isoform-specific antipeptide antibodies, were co- expressed on the apical surface of prostate epithelial cells in normal DLP. Androgen depletion did not significantly change the steady state levels of C-CAM message and protein expression in the DLP, although there was a change in the pattern of protein expression in these lobes. In contrast, C -CAM isoform messages and proteins were undetectable in normal ventral prostate (VP) but increased markedly in this lobe in response to castration, producing isoform ratios similar to those in DLP. These results demonstrate that coordinate expression of C- CAM isoforms is maintained in the VP following androgen depletion and suggest that androgen suppresses C-CAM expression in VP but not in DLP. These results suggest that balanced expression of L- and S-form C- CAM is important for normal prostate growth and differentiation
sj-docx-1-jpx-10.1177_23743735241240926 - Supplemental material for Alternative Payment Models and Patient-Reported Quality of Preparation for Discharge: A Retrospective Longitudinal Study
No full textSupplemental material, sj-docx-1-jpx-10.1177_23743735241240926 for Alternative Payment Models and Patient-Reported Quality of Preparation for Discharge: A Retrospective Longitudinal Study by Sunny C. Lin, Julia Adler-Milstein, John M. Hollingsworth and Andrew Ryan in Journal of Patient Experience</p
VMJ789783_Supplementary_Table_1 – Supplemental material for Association of HIV infection with age and symptomatic carotid atherosclerotic disease at the time of carotid intervention in the United States
No full textSupplemental material, VMJ789783_Supplementary_Table_1 for Association of HIV infection with age and symptomatic carotid atherosclerotic disease at the time of carotid intervention in the United States by Timothy C Lin, Brittany N Burton, Andrew Barleben, Martin Hoenigl and Rodney A Gabriel in Vascular Medicine</p
Directional effects of antiferromagnetic ordering on the electronic structure in NdSb
No full textThe recent discovery of unconventional surface state pairs, which give rise to Fermi arcs and spin textures, in antiferromagnetically ordered NdBi raised the interest in rare-earth monopnictides. Several scenarios of antiferromagnetic order have been suggested to explain the origin of these states with some of them being consistent with the presence of non-trivial topologies. In this study, we use angle-resolved photoemission spectroscopy (ARPES) and density-functional-theory (DFT) calculations to investigate the electronic structure of NdSb. We found the presence of distinct domains that have different electronic structure at the surface. These domains correspond to different orientations of magnetic moments in the AFM state with respect to the surface. We demonstrated remarkable agreement between DFT calculations and ARPES that capture all essential changes in the band structure caused by transition to a magnetically ordered state.This is a preprint from Kushnirenko, Yevhen, Brinda Kuthanazhi, Lin-Lin Wang, Benjamin Schrunk, Evan O'Leary, Andrew Eaton, P. C. Canfield, and Adam Kaminski. "Directional effects of antiferromagnetic ordering on the electronic structure in NdSb." arXiv preprint arXiv:2305.17085 (2023). doi: https://doi.org/10.48550/arXiv.2305.17085. Published as Kushnirenko, Yevhen, Brinda Kuthanazhi, Lin-Lin Wang, Benjamin Schrunk, Evan O'Leary, Andrew Eaton, Paul C. Canfield, and Adam Kaminski. "Directional effects of antiferromagnetic ordering on the electronic structure in NdSb." Physical Review B 108, no. 11 (2023): 115102. https://doi.org/10.1103/PhysRevB.108.115102
Band structure and charge ordering of Dirac semimetal EuAl 4 at low temperatures
No full textEuAl4 is proposed to host a topological Hall state. This material also undergoes four consecutive antiferromagnetic (AFM) transitions upon cooling below TN1 = 15.4 K in the presence of charge density wave (CDW) order that sets in below TCDW = 140 K. We use angle-resolved photoemission spectroscopy and density-functional-theory calculations to study how magnetic ordering affects the electronic properties in EuAl4. We found changes in the band structure upon each of the four consecutive AFM transitions including band splitting, renormalizations, and appearance of new bands forming additional Fermi sheets. In addition we also found significant enhancement of the quasiparticles' lifetime due to suppression of spin flip scattering, similar to what was previously reported for ferromagnetic EuCd2As2. Surprisingly, we observe that most significant changes in electronic properties occur not at TN1, but instead at the AFM3 to AFM4 transition, which coincides with the largest drop in resistivity.This is a preprint from Eaton, Andrew, Brinda Kuthanazhi, Paul C. Canfield, Benjamin Schrunk, Na Hyun Jo, Yevhen Kushnirenko, Evan O'Leary, Lin-Lin Wang, and Adam Kaminski. "Band structure and charge ordering of Dirac semimetal EuAl4 at low temperatures." arXiv preprint arXiv:2409.16468 (2024). doi: https://doi.org/10.48550/arXiv.2409.16468. Published as Eaton, Andrew, Brinda Kuthanazhi, Paul C. Canfield, Benjamin Schrunk, Na Hyun Jo, Yevhen Kushnirenko, Evan O'Leary, Lin-Lin Wang, and Adam Kaminski. "Band structure and charge ordering of Dirac semimetal EuAl 4 at low temperatures." Physical Review B 110, no. 12 (2024): 125150. doi: https://doi.org/10.1103/PhysRevB.110.125150
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