100,007 research outputs found

    Supplementary_tables_1-5 – Supplemental material for Clinicopathological and molecular differences in colorectal cancer according to location

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    Supplemental material, Supplementary_tables_1-5 for Clinicopathological and molecular differences in colorectal cancer according to location by Yu-Lun Hsu, Chun-Chi Lin, Jeng-Kai Jiang, Hung-Hsin Lin, Yuan-Tzu Lan, Huann-Sheng Wang, Shung-Haur Yang, Wei-Shone Chen, Tzu-Chen Lin, Jen-Kou Lin, Pei-Ching Lin and Shih-Ching Chang in The International Journal of Biological Markers</p

    Supplementary_Figure_1and2 – Supplemental material for Clinicopathological and molecular differences in colorectal cancer according to location

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    Supplemental material, Supplementary_Figure_1and2 for Clinicopathological and molecular differences in colorectal cancer according to location by Yu-Lun Hsu, Chun-Chi Lin, Jeng-Kai Jiang, Hung-Hsin Lin, Yuan-Tzu Lan, Huann-Sheng Wang, Shung-Haur Yang, Wei-Shone Chen, Tzu-Chen Lin, Jen-Kou Lin, Pei-Ching Lin and Shih-Ching Chang in The International Journal of Biological Markers</p

    Shih Ching Wang and Wen-Lin Wang, Class of 1921

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    This photograph shows Shih Ching Wang and Wen-Lin Wang, class of 1921 of the International YMCA College, now Springfield College. Shih Ching Wang (back) and Wen-Lin Wang (front) are in a dormitory room, sitting in a bed and in a chair respectively, with Shih Ching holding a flute and Wen-Lin holding a sanxian. It seems that they are rehearsing a piece of music.A caption in the back states: "Mar 16 1920"

    mechanization of lily microbulb

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    mechanization of lily microbulb multiplication operations. ta-te lin & ching-lu hsieh. department of agricultural machinery engineering.. national taiwan university.. taipei. taiwan. roc. mechanization of lily microbul

    Gardens, Chinese: Shizi Lin Yuan Garden, Suzhou, China [005]

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    Photograph of Shizi Lin Yuan Garden, Suzhou, ChinaShizi Lin Yuan Garden, Suzhou, China

    Gardens, Chinese: Shizi Lin Yuan Garden, Suzhou, China [011]

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    Photograph of people on stone boat, Shizi Lin Yuan Garden, Suzhou, ChinaStone boat, Shizi Lin Yuan Garden, Suzhou, China

    An Analysis of <i>Judge Lin</i>

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    Biography of Lin Wen Zhong Gong has another way to call, that is Judge Lin. The leading character is Lin Ze-Xu. This book is based on functionary experience of Lin Ze-Xu, with the captivating plots of court case, helping by highly skilled military attach\uc3\ua9s and chivalrous knights, and the history facts of Opium War. It makes Lin Ze-Xu\ue2s Confucian temperament and tragic mood more, also contrasts with author\ue2s sorrow and furiousness for the politics at the time. History, court case, martial arts\ue2\ua6\ue2\ua6etc. are essence of this book and it broadens the way of this writing style. The topic of the thesis is \ue2An Analysis of Judge Lin\ue2. The following thesis will be divided into six different chapters. The introduction is Chapter one of the thesis, which is including researching motive and purpose, literature review of predecessors, researching version by existing information, raising questions, choosing research methods and arranging chapters. In chapter Two, I discuss the study of characters of Lin Ze-Xu, also makes a deep analysis of author\u27s purpose of writing him. In chapter Three, I analyze supporting actors and actress. Meanwhile, I illustrate author\u27s purpose of writing supporting actress because the author had different manner to describe supporting actress. Moving to the Chapter Four, I mainly focus on the plots of Judge Lin, and organize cases of Lin Ze-Xu and his subordinates to understand features of cases. In Chapter Five, I represent the causes of Opium War. China and England had difference of opinions of opium. Therefore, it is easier to comprehend what the author\u27s purpose is. In the last chapter I summarize the main points of the preceding chapters and confirm particularity of Judge Lin

    List of Christian women of Lin Ching, China

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    List of Lin Ching church Female Christians, with descriptive comment

    The stem cell E3-ligase Lin-41 promotes liver cancer progression through inhibition of microRNA-mediated gene silencing

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    Lin-41 is a stem cell-specific E3 ligase and a known target of the tumour suppressor microRNA (miRNA) let-7. Lin-41 was recently reported to mediate ubiquitylation and degradation of the miRNA pathway protein Ago2. We demonstrate that Lin-41 is over-expressed in hepatocellular carcinoma (HCC). Lin-41 over-expression correlates with high a-fetoprotein level, high tumour grade and high tumour stage and predicts early tumour recurrence. Lin-41 is a strong predictor of poor long-term survival for patients with HCC. Lin-41 knock-down by RNA interference in HCC cell lines Huh7 and Hep3B suppressed proliferation in vitro and reduced in vivo tumour growth in NOD/SCID mice. On the other hand, over-expression of Lin-41 in the HCC cell line SK-Hep1 enhanced tumourigenicity. Over-expression and knock-down of Lin-41 led to inverse changes in the levels of Ago1 and Ago2 proteins. Over-expression of Ago1 and Ago2 reduced in vivo tumour growth. Lin-41 over-expression suppressed let-7 activity in HCC cell lines and expression of Lin-41 enhanced the expression of let-7-regulated oncogenes c-Myc, Lin-28B, HMGA2 and type 1 insulin-like growth factor receptor (IGF1R). Expression of Lin-28B and c-Myc enhanced the expression of Lin-41. Chromatin immunoprecipitation and reporter assays revealed direct association of c-Myc with the Lin-41 promoter, resulting in transcriptional transactivation. Our results indicate that Lin-41 plays an important role in the growth of HCC by regulating RISC complex proteins Ago1 and Ago2 to inhibit miRNA-mediated gene silencing and promote the expression of oncogenic proteins. Lin-41 is also a strong prognostic factor for patients with HCC. Copyright (C) 2012 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd

    Gardens, Chinese: Shizi Lin Yuan Garden, Suzhou, China [017]

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    Photograph of corner of garden wall (with six windows), possibly at Shizi Lin Yuan Garden, Suzhou, ChinaWall with windows, possibly at Shizi Lin Yuan Garden, Suzhou, China. 32-L
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