2,672,695 research outputs found
Dr. Lin Sun, CAU, March 2013
This video is a conversation with Dr. Lin Sun. Dr. Sun talks about an exhibit at the Woodruff Library titled "At The Boundary." Jordan Moore, AUC Woodruff Library, is the interviewer
An Analysis of <i>Judge Lin</i>
Biography of Lin Wen Zhong Gong has another way to call, that is Judge Lin. The leading character is Lin Ze-Xu. This book is based on functionary experience of Lin Ze-Xu, with the captivating plots of court case, helping by highly skilled military attach\uc3\ua9s and chivalrous knights, and the history facts of Opium War. It makes Lin Ze-Xu\ue2s Confucian temperament and tragic mood more, also contrasts with author\ue2s sorrow and furiousness for the politics at the time. History, court case, martial arts\ue2\ua6\ue2\ua6etc. are essence of this book and it broadens the way of this writing style.
The topic of the thesis is \ue2An Analysis of Judge Lin\ue2. The following thesis will be divided into six different chapters. The introduction is Chapter one of the thesis, which is including researching motive and purpose, literature review of predecessors, researching version by existing information, raising questions, choosing research methods and arranging chapters. In chapter Two, I discuss the study of characters of Lin Ze-Xu, also makes a deep analysis of author\u27s purpose of writing him. In chapter Three, I analyze supporting actors and actress. Meanwhile, I illustrate author\u27s purpose of writing supporting actress because the author had different manner to describe supporting actress. Moving to the Chapter Four, I mainly focus on the plots of Judge Lin, and organize cases of Lin Ze-Xu and his subordinates to understand features of cases. In Chapter Five, I represent the causes of Opium War. China and England had difference of opinions of opium. Therefore, it is easier to comprehend what the author\u27s purpose is. In the last chapter I summarize the main points of the preceding chapters and confirm particularity of Judge Lin
Nan Lin and social capital
Nan Lin’s work on social capital is a significant, unique contribution. My purpose here is to explain that statement by looking at the work in historical context. Figure 2.1 is an index for much of the story to be told. The horizontal axis is time, beginning in 1975 when Nan Lin was at the State University of New York at Albany (now the University of Albany), through his 1990 move to Duke University, and on to 2010
Du lin sauvage au lin cultivé
National audienceLe lin actuellement cultivé correspond à l'espèce domestique (Linum usitatissimum L.) qui dérive de l'exploitation de l'ancêtre sauvage, le lin bisannuel ou lin à feuilles étroites (Linum bienne Mill.). L'adaptabilité du lin sauvage à différentes conditions environnementales permet d'expliquer sa large répartition géographique, du Caucase au Nord de l'Afrique et de la Méditerranée à l'Europe occidental
Spatial Chow-Lin Methods for Data Completion in Econometric Flow Models
Flow data across regions can be modeled by spatial econometric models, see LeSage and Pace (2009). Recently, regional studies became interested in the aggregation and disaggregation of flow models, because trade data cannot be obtained at a disaggregated level but data are published on an aggregate level. Furthermore, missing data in disaggregated flow models occur quite often since detailed measurements are often not possible at all observation points in time and space. In this paper we develop classical and Bayesian methods to complete flow data. The Chow and Lin (1971) method was developed for completing disaggregated incomplete time series data. We will extend this method in a general framework to spatially correlated flow data using the cross-sectional Chow-Lin method of Polasek et al. (2009). The missing disaggregated data can be obtained either by feasible GLS prediction or by a Bayesian (posterior) predictive density.Missing values in spatial econometrics, MCMC, non-spatial Chow-Lin (CL) and spatial Chow-Lin (SCL) methods, spatial internal flow (SIF) models, origin and destination (OD) data
LIN-39 does not regulate TRN fate markers in AVM.
(A) AVM was posteriorly displaced in lin-39(n1760) mutants, but the expression of TRN fate marker uIs115[mec-17p::TagRFP] was not affected in lin-39 mutants. (B) The displaced AVM also expressed the TRN fate marker zdIs5[mec-4p::GFP] in lin-39 mutants. Scale Bars = 100 μm. (TIF)</p
The stem cell E3-ligase Lin-41 promotes liver cancer progression through inhibition of microRNA-mediated gene silencing
Lin-41 is a stem cell-specific E3 ligase and a known target of the tumour suppressor microRNA (miRNA) let-7. Lin-41 was recently reported to mediate ubiquitylation and degradation of the miRNA pathway protein Ago2. We demonstrate that Lin-41 is over-expressed in hepatocellular carcinoma (HCC). Lin-41 over-expression correlates with high a-fetoprotein level, high tumour grade and high tumour stage and predicts early tumour recurrence. Lin-41 is a strong predictor of poor long-term survival for patients with HCC. Lin-41 knock-down by RNA interference in HCC cell lines Huh7 and Hep3B suppressed proliferation in vitro and reduced in vivo tumour growth in NOD/SCID mice. On the other hand, over-expression of Lin-41 in the HCC cell line SK-Hep1 enhanced tumourigenicity. Over-expression and knock-down of Lin-41 led to inverse changes in the levels of Ago1 and Ago2 proteins. Over-expression of Ago1 and Ago2 reduced in vivo tumour growth. Lin-41 over-expression suppressed let-7 activity in HCC cell lines and expression of Lin-41 enhanced the expression of let-7-regulated oncogenes c-Myc, Lin-28B, HMGA2 and type 1 insulin-like growth factor receptor (IGF1R). Expression of Lin-28B and c-Myc enhanced the expression of Lin-41. Chromatin immunoprecipitation and reporter assays revealed direct association of c-Myc with the Lin-41 promoter, resulting in transcriptional transactivation. Our results indicate that Lin-41 plays an important role in the growth of HCC by regulating RISC complex proteins Ago1 and Ago2 to inhibit miRNA-mediated gene silencing and promote the expression of oncogenic proteins. Lin-41 is also a strong prognostic factor for patients with HCC. Copyright (C) 2012 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd
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