350 research outputs found
Optimization and sensitivity analysis of computer simulation models by the score function method
No full textExperimental Design;Simulation;Optimization;Queueing Theory
Concerted upregulation of CLP36 and smooth muscle actin protein expression in human endometrium during decidualization
No full textThe human endometrium prepares for implantation of the blastocyst by reorganization of its whole cellular network. Endometrial stroma cells change their phenotype starting around the 23rd day of the menstrual cycle. These predecidual stroma cells first appear next to spiral arteries, and after implantation these cells further differentiate into decidual stroma cells. The phenotypical changes in these cells during decidualization are characterized by distinct changes in the actin filaments and filament-related proteins such as α-actinin. The carboxyterminal LIM domain protein with a molecular weight of 36 kDa (CLP36) is a cytoskeletal component that has been shown to associate with contractile actin filaments and to bind to α-actinin supporting a role for CLP36 in cytoskeletal reorganization and signal transduction by binding to signaling proteins. The expression patterns of CLP36, α-actinin and actin were studied in endometrial stroma cells from different stages of the menstrual cycle and in decidual stroma cells from the 6th week of gestation until the end of pregnancy. During the menstrual cycle, CLP36 is only expressed in the luminal and glandular epithelium but not in endometrial stroma cells. During decidualization and throughout pregnancy, a parallel upregulation of CLP36 and smooth muscle actin, an early marker of decidualization in the baboon, was observed in endometrial decidual cells. Since both proteins maintain a high expression level throughout pregnancy, a role of both proteins is suggested in the stabilization of the cytoskeleton of these cells that come into close contact with invading trophoblast cells. Copyright (C) 2005 S. Karger AG, Basel
Perturbation of frame sequences and its applications to shift-invariant spaces
No full textAbstractWe generalize the main result in [O. Christensen, H.O. Kim, R.Y. Kim, J.K. Lim, Perturbation of frame sequences in shift-invariant spaces, J. Geom. Anal. 15 (2005) 181–191] in order to make it comparable with existing results. Then we compare the special cases of the three results in the literature in the setting of the perturbation of the generating sets of finitely generated shift-invariant spaces of L2(Rd)
Current Social and Cultural Technologies as the Means of Personality Development
No full textЛитвак Римма Алексеевна, доктор педагогических наук, профессор, заведующий кафедрой
педагогики и психологии, Челябинский государственный институт культуры, г. Челябинск,
[email protected]. R.Y. Litvak, [email protected]
Chelyabinsk State Institute of Culture, Chelyabinsk, Russian FederationВ статье раскрывается значение, особенности социокультурных технологий в развитии личности. Уточнены основные понятия. Представлены исследования ученых, посвященные социокультурным технологиям. Выделены общие черты и структура социокультурных технологий. Определены требования к педагогическим технологиям (концептуальность, антропоцентризм, ситуативность, контекстуальность). Автор отмечает отличие
и уникальность социокультурных технологий, особое внимание уделяет при этом содержательным характеристикам социокультурных технологий личностного развития. Выделяет наиболее эффективные традиционные и инновационные средства социокультурной
деятельности, а также методы и формы организации социокультурной деятельности, направленной на развитие личности. Представлены и охарактеризованы инновационные методики (социокультурное проектирование, бизнес-инкубаторы, технопарки, блоги, виртуальные музеи, перевернутое, витагенное, модульное, мобильное обучение и онлайн технологии) и способы личностного развития в образовательной и социокультурной сферах. The article reveals the meaning, peculiarities of social and cultural technologies in the development
of personality. The basic concepts are specified. Studies of scientists dedicated to social
and cultural technologies are presented. General features and structure of social and cultural
technologies are distinguished. The requirements for pedagogical technologies (conceptual importance,
anthropocentrism, situation and context consideration) are defined. The author notes
the difference and uniqueness of social and cultural technologies, paying special attention to
the content characteristics of social and cultural technologies of personal development. The author
identifies the most effective traditional and innovative means of social and cultural activity,
as well as the methods and forms of organization of social and cultural activities aimed at the development
of the individual. Innovative methods (social and cultural design, business incubators,
technology parks, blogs, virtual museums, flipped classroom, vital, modular, mobile training and
online technologies) and the ways of personal development in the educational, social and cultural
spheres are presented and characterized
A comparative study of the Finnish 4-H organization and the Wisconsin 4-H organization
No full textPlan BThe education of today’s youth, tomorrow’s future, is the focus of the 4-H organization. The aim of the 4-H program is to develop life skills in youth using hands-on learning. 4-H began in the heartland of America in the early 1900’s and soon stretched around the globe. 4-H or a partner organization of 4-H can be found in over 63 countries in the world (V. Gobeli, personal communication, February 25, 2002). The programming, structure, and principles of 4-H programs around the world are all based on the program that began in the United States, but the methods used are different in every country. It is even different among states in the United States. Each program has unique ideas used in the education of youth, but little communication exists to share these ideas among countries. The purpose of this study is to compare another country’s 4-H program to the program that has been long established in Wisconsin. The goal of the study is to show the similarities and difference of two programs that have been created using the same theme, “learning by doing.” Due to the scope of this research, the researcher chose to look only at one country. The country of Finland was chosen for comparison because of its location, similar structure, and its well-established example of European youth programming. The researcher looked at the history of the two programs to help establish the similarities and difference that might exist. The Finnish 4-H Federation began after two men visited the United States and observed the success of club work administered by the United States Department of Agriculture. The program ideas were changed to fit the needs of the Finnish people, with the key concept of life skill development remaining the same. The researcher also found that many articles have been written to show an importance in international programming and international travel. The research was done using ethnographic research along with a qualitative written survey and various interviews. The written survey was used to gain basic information before ethnographic research began. The research revealed that although the programs have the same basic goal, the two programs are very different. The largest differences were seen in projects offered, staff roles, leaders participation, and competition. It was found that both 4-H programs contained ideas of superior quality. If these ideas were shared, it could help to improve the program in the other country. The research not only compared the two programs, but also recommended further programs or studies that could be established based on the research performed
Revisiting "the Kingdom of Daughters": Gender Discourse on Flowers in the Mirror from the Middle Qing
No full text由於胡適在五四時期的詮釋，李汝珍的小說《鏡花緣》長期以來被認為是古典文學中提倡女權的先驅，對傳統中國的婦女問題有所發見。本文欲從不同時代、不同位置的讀者對《鏡花緣》的閱讀中，瞭解這樣的性別論述如何透過對古典文本抱持現實關懷的詮釋中建構而成，並將其影響力延續至今。作者企圖從此文導引出來的問題是：中國近代女權論述的建構中隱含的兩種預設──本質化的「西方」與「傳統」，如何影響時人對歷史文獻的評估。此種基於時代關懷的論述方式具有很大的影響力，使得後來的讀者面對的不僅是文本本身，而更是與晚清與五四時期的讀者進行對話。Because of Hu Shi’s interpretation during the May-fourth era, Li Ruzhen’s novel, Flowers in the Mirror (Jing-hua Yuan), has been regarded as a forerunner of the advocacy of women’s rights in classical literature and as having discovered the problems of women’s plight in traditional China. This article attempts to look over the various readings of Flowers in the Mirror from the readers of different eras and positions, in order to realize how this gender discourse was constructed on the basis of the interpretation of classical texts with contemporary concerns, and has kept its effectiveness even now.
The main question the author intends to pursue in this article is: how do the two assumptions, the essentialist “western” and the essentialist “tradition”, underlying the construction of feminist discourse from late Qing to May-fourth era, impinge on our evaluation of historical documents. This kind of discourse, derived from their contemporary concern, has great effectiveness, and causes the subsequent readers, not only to face the text itself, but also to converse with the readers of May-fourth era and late Qing
Geographical point cloud modelling with the 3D medial axis transform
No full textA geographical point cloud is a detailed three-dimensional representation of the geometry of our geographic environment. Using geographical point cloud modelling, we are able to extract valuable information from geographical point clouds that can be used for applications in asset management, crisis management, city and landscape planning, and environmental simulations.During this process the point cloud is semantically enriched, e.g. by performing classification, and structurally enriched, e.g. by performing segmentation or surface reconstruction. In this thesis I propose a new approach to geographical point cloud modelling based on the 3D Medial Axis Transform (MAT), a skeleton-like representation of shapes that explicitly models both the topology and the geometry of shapes. While the 3D MAT has been used before in other fields, its application to geographical point clouds is novel. Advantages of the MAT over existing mostly 2.5D and boundary representation-based methods include that 1) it is fully 3D, 2) it can be used to intuitively structure and decompose a point cloud into objects, 3) it clearly separates a point cloud into interior and exterior volumes, and 4) it is able to compactly characterise geometrical properties of a shape though its local medial geometry. I make three core contributions. First, I explain how to robustly approximate the 3D MAT for large real-world geographical point clouds. This is critical for geographical point clouds because they are inherently noisy due to the challenging acquisition conditions and the fact that the MAT in itself is highly sensitive to noise. Second, I show how to structure the MAT into a connected set of medial sheets that form so-called 'medial clusters' that give us a natural decomposition of the point cloud into objects. Third, I demonstrate how the MAT can be applied for feature aware point cloud simplification and visualisation, visibility analysis, watercourse detection, and building detection. Due to noise and limitations in the point density of geographical point clouds, the MAT performs best for objects that have a clearly defined volume in the point cloud such as for example houses and landscape features. It is less suitable for object like trees and thin street furniture. The core result of this thesis is that I prove that the 3D MAT is a useful and practically viable tool for geographical point cloud modelling.Urban Data Scienc
Approximating the Medial Axis Transform of LiDAR point clouds (POSTER)
No full textOTBArchitecture and The Built Environmen
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