1,720,989 research outputs found
Automatic Computer-Based Tracings (ACT) in Longitudinal 2-D Ultrasound Images Using Different Scanners
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The speed of reinfusion affects the vascular system during ozone major autohemotherapy
Full text linkOzone major autohemotherapy (O-MAHT) is a way of ozonetherapy administration consisting of drawing patient's venous blood, mixing with oxygen/ozone, and reinfusing it into the vein. Some ozone therapists reported side effects during the O-MAHT, but the origin has not been described yet. We investigated the effect of blood drawing velocity during O-MAHT to see its effects on the vascular system and symptomatology. We administered O-MAHT to 11 subjects, and we interleaved fast and slow reinfusions. We monitored cerebral macrocirculation with transcranial Doppler (TCD) and tissue microcirculation with near-infrared spectroscopy (NIRS). Annoying symptoms appeared just during the fast reinfusion periods. NIRS and TCD parameters revealed vasoconstriction during fast reinfusion and improved metabolism during slow reinfusion. Overall, our investigation well discriminated fast from slow reinfusion velocity
Entropy analysis of muscular near-infrared spectroscopy (NIRS) signals during exercise programme of type 2 diabetic patients: Quantitative assessment of muscle metabolic pattern.
No full textDiabetes mellitus (DM) is a metabolic disorder that is widely rampant throughout the worldpopulation these days. The uncontrolled DM may lead to complications of eye, heart, kidneyand nerves. The most common type of diabetes is the type 2 diabetes or insulin-resistantDM.Near-infrared spectroscopy (NIRS) technology is widely used in non-invasive monitoringof physiological signals. Three types of NIRS signals are used in this work: (i) variation in theoxygenated haemoglobin (O2Hb) concentration, (ii) deoxygenated haemoglobin (HHb), and(iii) ratio of oxygenated over the sum of the oxygenated and deoxygenated haemoglobinwhich is defined as: tissue oxygenation index (TOI) to analyze the effect of exercise ondiabetes subjects.The NIRS signal has the characteristics of non-linearity and non-stationarity. Hence, thevery small changes in this time series can be efficiently extracted using higher order statis-tics (HOS) method. Hence, in this work, we have used sample and HOS entropies to analyzethese NIRS signals. These computer aided techniques will assist the clinicians to diagnoseand monitor the health accurately and easily without any inter or intra observer variability.Results showed that after a one-year of physical exercise programme, all diabetic subjectsincreased the sample entropy of the NIRS signals, thus revealing a better muscle perfor-mance and an improved recruitment by the central nervous system. Moreover, after oneyear of physical therapy, diabetic subjects showed a NIRS muscular metabolic pattern thatwas not distinguished from that of controls.We believe that sample and bispectral entropy analysis is need when the aim is to comparethe inner structure of the NIRS signals during muscle contraction, particularly when dealingwith neuromuscular impairments
Long-term cerebrovascular reactivity mediatedby ozone autohemotherapy: a NIRS study
No full textOzone autohemotherapy is an emerging
therapeutic technique. A validated and standard methodology to
assess the effect of such therapy is still lacking. We used a nearinfrared
spectroscopy system (NIRS) to monitor the cerebral
oxygenation of 8 subjects (6 neurological) before, during, and
after ozone autohemotherapy. The oxygen concentration in
brain tissue markedly increased about 1-2 hours after therapy.
The time-frequency analysis of the NIRS signals revealed an
increasing activity in the LF frequency band related to the
vascular autoregulation. This preliminary study showed that
NIRS could be useful to show the effects of ozone
autohemotherapy at cerebral level, in a long term monitoring
Ozone autohemotherapy induces long-term cerebral metabolic changes in multiple sclerosis patients.
No full textOzone autohemotherapy is an emerging therapeutic technique that is gaining increasing importance in treating neurological disorders. A validated and standard methodology to assess the effect of such therapy on brain metabolism and circulation is however still lacking. We used a near-infrared spectroscopy (NIRS) system to monitor the cerebral metabolism and a transcranial Doppler (TCD) to monitor the blood flow velocity in the middle cerebral arteries. Fifty-four subjects (32 neurological patients and 22 controls) were tested before, during, and after ozone autohemotherapy. We monitored the concentration changes in the level of oxygenated and deoxygenated haemoglobin, and in the level of the Cytochrome-c-oxidase (CYT-c). As a primary endpoint of the work, we showed the changes in the brain metabolism and circulation of the entire population. The concentration of oxygenated haemoglobin increased after the reinjection of the ozoned blood and remained higher than the beginning for another 1.5 hours. The concentration of the deoxygenated haemoglobin decreased during the therapy and the CYT-c concentration markedly increased about 1 hour after the reinjection. No significant changes were observed on the blood flow velocity. As secondary endpoint, we compared the NIRS metabolic pattern of 20 remitting-relapsing multiple sclerosis (MS) patients against 20 controls. We showed that by using only 7 NIRS variables it was possible to characterize the metabolic brain pattern of the two groups of subjects. The MS subjects showed a marked increase of the CYT-c activity and concentration about 40 minutes after the end of the autohemotherapy, possibly revealing a reduction of the chronic oxidative stress level typical of MS sufferers. From a technical point of view, this preliminary study showed that NIRS could be useful to show the effects of ozone autohemotherapy at cerebral level, in a long-term monitoring. The clinical result of this study is the quantitative measurement of the CYT-c level changes in MS induced by ozone autohemotherapy
Carotid plaque characterization with contrast-enhanced ultrasound imaging and its histological validation
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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