8,042 research outputs found
cy-xu/cosmic-conn: dependency optimization
No full text<h2>What's Changed</h2>
<ul>
<li>remove development dependencies from inference install</li>
</ul>
<h2>Binaries</h2>
<p>https://pypi.org/project/cosmic-conn/</p>
<h2>Full Changelog</h2>
<p>https://github.com/cy-xu/cosmic-conn/compare/v0.4.1...v0.5.0</p>
Letter from Cy Donner to Michi Weglyn, June 2, 1967
No full textA letter from Cy Donner to Michi Weglyn encouraging her to come out to California to talk to producers about two shows called "Youthquake" and "Pretty Talk".These materials are from box 73 and 74 of the Frank Chin Papers. The Frank Chin Papers contain personal and professional correspondence between Frank Chin and Michi Weglyn relating to particular projects on which either author was working as well as files related to the Day of Remembrance Tribute to Michi Weglyn
CY-09 Alleviates the Depression-like Behaviors via Inhibiting NLRP3 Inflammasome-Mediated Neuroinflammation in Lipopolysaccharide-Induced Mice
No full textDepression
is a serious mental illness, mainly characterized
as
large mood swings and sleep, diet, and cognitive function disorders.
NLPR3, one of the inflammasomes that can be activated by a variety
of stimuli to promote the maturation and secretion of pro-inflammatory
cytokines, has been considered to be involved in the pathophysiology
of depression. In this study, the putative role of CY-09, a selective
and direct inhibitor of NLRP3, was evaluated in the lipopolysaccharide
(LPS)-induced mice. The results of the study indicated that CY-09
significantly decreased the levels of NLRP3 in the hippocampus of
LPS-induced mice. In addition, CY-09 increased the sucrose preference
and shortened the immobility time in LPS-induced mice, suggesting
the antidepressant-like effects of inhibiting NLRP3 inflammasome.
Biochemical analysis showed that LPS significantly activated the NLRP3/ASC/cytokine
signaling pathway and caused microglial activation, while CY-09 prevented
the changes. Moreover, CY-09 increased the brain-derived neurotrophic
factor (BDNF) only in microglia but not in the whole hippocampus.
Meanwhile, CY-09 did not promote neurogenesis in the hippocampus of
LPS mice. In conclusion, the results of the study showed that the
antidepressant-like effects of NLRP3 inhibitor CY-09 were mediated
by alleviating neuroinflammation in microglia and independent of the
neurotrophic function in the hippocampus
Risk assessment of active smoking: smoking-attributable mortality and years of potential life lost in Taiwan, 1980 and 1992
No full textFTIR spectra of the CY, PVA, PVA/CNF, CY/PVA and CY/PVA/CNF films.
No full textFTIR spectra of the CY, PVA, PVA/CNF, CY/PVA and CY/PVA/CNF films.</p
Outcome of medium-dose VP-16/CY/TBI superior to CY/TBI as a conditioning regimen for allogeneic stem cell transplantation in adult patients with acute lymphoblastic leukemia
Full text linkThe choice of conditioning regimen before allogeneic stem cell transplantation (SCT) in patients with acute lymphoblastic leukemia (ALL) is important. We retrospectively compared outcomes of medium-dose VP-16/cyclophosphamide/total body irradiation (VP/CY/TBI) regimen and CY/TBI. Five hundred and twenty-nine patients (VP/CY/TBI: n = 35, CY/TBI: n = 494) who met all of the following criteria were compared: first time for SCT, aged 15-59 years; first or second complete remission at SCT; bone marrow or peripheral blood as stem cell source; and HLA phenotypically matched donor. Median age of the patients was 34 years, and patients who received VP/CY/TBI were younger (28 years vs. 34 years, P = 0.02). Cumulative incidences of relapse and non-relapse mortality (NRM) were higher for patients who received CY/TBI (P = 0.01 for relapse, P < 0.01 for NRM). After a median follow-up period of 36.9 months, 5-year overall survival (OS) rates were 82.2% in the VP/CY/TBI group and 55.2% in the CY/TBI group. OS, and disease-free survival (DFS) in the VP/CY/TBI group were shown to be significantly better by multivariate analysis [hazard ratio: 0.21 (95% confidence interval: 0.06-0.49) for DFS, hazard ratio: 0.25 (95% confidence interval: 0.08-0.59) for OS]. VP/CY/TBI was associated with a lower relapse rate and no increase in NRM, resulting in better survival than that in CY/TBI for adult ALL patients
Guiron le Courtois, translaté de latin en françois par Luce du Châtel du Gat. Tome II : « Cy commence li seconds livres de Guiron le Courtois »
No full textNumérisation effectuée à partir d'un document original.Commencement : « Or dist li contes que li rois Melyadus demoura ou chastel... » — Fin : « ...et encore est communement son nom par toute Engleterre. — Cy fine le tiers et derrenier livre de Guiron le Courtois.
The intraday bid-ask spread behaviour of the JPY/USD exchange rate in the EBS electronic brokerage system
No full text[[abstract]]Using a sophisticated tool of the Periodic-Generalized Autoregressive Conditional Heteroscedastic (P-GARCH) model, this article investigates the market institutional effects of the determining role of trading activities and exchange rate volatility on the intraday behaviour of the 15-minute JPY/USD exchange rate bid-ask spreads in the Electronic Broking Service (EBS) of electronic brokerage market for the period from 1 January 2003 to 31 December 2005. We find that the exchange rate volatility both significantly and positively affects the bid-ask spreads, while the number of deals and quotation changes negatively affect the bid-ask spreads. These results are similar to those of past studies. We also find that a U-shaped pattern exists in the Tokyo trading hours and an inverted U-shaped pattern in the London trading hours, in addition to a round clock inverted U-shaped pattern of spread volatility. This inverted U-shaped pattern may be caused by unexpected news arrivals. The spread behaviour of the EBS global electronic broking market is not different from that of other electronic interdealer quotation markets and electronic broking markets.[[note]]SSC
Robustness Comparison of the Pena-Box Model and the Factor Model to Extract Useful Predictors
No full text[[abstract]]To forecast the Consumer Price Index, adopting dimension reduction to extract useful predictors from a large set of monthly macroeconomic time series is a way to improve forecasting accuracy. This article compares two methods for extracting predictors, including the well-known classical factor model and the Pena-Box Model, which is a dynamic factor model. Compared with the classical factor model, the Pena-Box Model is more robust with respect to misidentifying models since it captures the time-effect relationship of original variables. Both simulations and empirical studies on forecasting the Consumer Price Index of the Four Asian Tigers confirm the advantages of the Pena-Box Model.[[note]]SSC
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