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Une évaluation des effets de la pandémie de COVID-19 sur la prise en charge et le pronostic des personnes en insuffisance rénale chronique terminale fondée sur le Système National des Données de Santé.
No full textThe first study in this thesis estimated the impact of the pandemic on the survival of kidney transplant recipients (KTR). Incident persons with end stage kidney disease between 2015 and 2020, and who received a kidney transplant during this period were followed-up from their transplantation date to December 31, 2021. The estimated excess risk during the pandemic period was concentrated among KTR with a history of COVID-19 related hospitalization. For those without such history, survival rates during the pre-pandemic and pandemic periods did not significantly differ. Notably, it was not until the third dose of the vaccine that a significant reduction in the risk of death was observed in kidney transplant recipients; The second study in this thesis examined the evolving impact of the pandemic on the management and survival of individuals with end-stage renal disease treated by dialysis, with incident cases between 2015 and 2021, and follow-up until December 31, 2022. The analyses indicated both direct and indirect adverse effects of the pandemic on the probability of dialysis patients receiving a kidney transplant during this period. Excess risk was observed only during epidemic waves and in individuals with a history of hospitalization for COVID-19. No indirect impact of the pandemic on dialysis survival was detected. Receiving booster doses was associated with improved survival. Finally, the estimated risks during the pandemic for dialysis patients and matched controls were similar, suggesting that the risks observed for dialysis patients were more related to their overall health context than to kidney disease.La première étude composant cette thèse a estimé l'impact de la période pandémique sur la survie de transplantés rénaux incidents en France entre 2015 et 2020, et suivis jusqu'au 31/12/2021. Le surrisque estimé durant la période pandémique était concentré chez les transplantés ayant un historique d'hospitalisation pour COVID-19, mais pour ceux sans un tel historique, la survie pendant la période pré-pandémique et pandémique n'était pas significativement différente. De plus, ce n'est qu'à partir de la troisième dose de vaccin que l'on observe une diminution significative du risque de décès chez les transplantés rénaux. La seconde étude composant cette thèse a examiné l'évolution de l'impact de la pandémie sur la prise en charge et la survie des personnes en insuffisance rénale chronique terminale traitée par dialyse, incidentes entre 2015 et 2021, et suivies jusqu'au 31/12/2022. Les analyses indiquent un impact direct et indirect défavorable de la période pandémique sur la probabilité des dialysés de bénéficier d'une greffe de rein pendant cette période. Un surrisque était observé uniquement durant les vagues épidémiques et chez les personnes ayant un historique d'hospitalisation pour COVID-19. Aucun impact indirect de la période pandémique sur la survie des dialysés n'a été détecté. Recevoir des doses de rappel vaccinal était associé à une meilleure survie. Enfin, les risques estimés pendant la période pandémique chez les dialysés et des témoins appariés étaient similaires, les risques des dialysés observés apparaissent donc plus liés à leur santé contextuelle, que reliés à la maladie rénale stricto sensu
Evaluation of the effects of the COVID-19 pandemic on the management and prognosis of persons with end-stage kidney disease, based on the French National Health Data System.
No full textLa première étude composant cette thèse a estimé l'impact de la période pandémique sur la survie de transplantés rénaux incidents en France entre 2015 et 2020, et suivis jusqu'au 31/12/2021. Le surrisque estimé durant la période pandémique était concentré chez les transplantés ayant un historique d'hospitalisation pour COVID-19, mais pour ceux sans un tel historique, la survie pendant la période pré-pandémique et pandémique n'était pas significativement différente. De plus, ce n'est qu'à partir de la troisième dose de vaccin que l'on observe une diminution significative du risque de décès chez les transplantés rénaux. La seconde étude composant cette thèse a examiné l'évolution de l'impact de la pandémie sur la prise en charge et la survie des personnes en insuffisance rénale chronique terminale traitée par dialyse, incidentes entre 2015 et 2021, et suivies jusqu'au 31/12/2022. Les analyses indiquent un impact direct et indirect défavorable de la période pandémique sur la probabilité des dialysés de bénéficier d'une greffe de rein pendant cette période. Un surrisque était observé uniquement durant les vagues épidémiques et chez les personnes ayant un historique d'hospitalisation pour COVID-19. Aucun impact indirect de la période pandémique sur la survie des dialysés n'a été détecté. Recevoir des doses de rappel vaccinal était associé à une meilleure survie. Enfin, les risques estimés pendant la période pandémique chez les dialysés et des témoins appariés étaient similaires, les risques des dialysés observés apparaissent donc plus liés à leur santé contextuelle, que reliés à la maladie rénale stricto sensu.The first study in this thesis estimated the impact of the pandemic on the survival of kidney transplant recipients (KTR). Incident persons with end stage kidney disease between 2015 and 2020, and who received a kidney transplant during this period were followed-up from their transplantation date to December 31, 2021. The estimated excess risk during the pandemic period was concentrated among KTR with a history of COVID-19 related hospitalization. For those without such history, survival rates during the pre-pandemic and pandemic periods did not significantly differ. Notably, it was not until the third dose of the vaccine that a significant reduction in the risk of death was observed in kidney transplant recipients; The second study in this thesis examined the evolving impact of the pandemic on the management and survival of individuals with end-stage renal disease treated by dialysis, with incident cases between 2015 and 2021, and follow-up until December 31, 2022. The analyses indicated both direct and indirect adverse effects of the pandemic on the probability of dialysis patients receiving a kidney transplant during this period. Excess risk was observed only during epidemic waves and in individuals with a history of hospitalization for COVID-19. No indirect impact of the pandemic on dialysis survival was detected. Receiving booster doses was associated with improved survival. Finally, the estimated risks during the pandemic for dialysis patients and matched controls were similar, suggesting that the risks observed for dialysis patients were more related to their overall health context than to kidney disease
Une évaluation des effets de la pandémie de COVID-19 sur la prise en charge et le pronostic des personnes en insuffisance rénale chronique terminale fondée sur le Système National des Données de Santé.
No full textThe first study in this thesis estimated the impact of the pandemic on the survival of kidney transplant recipients (KTR). Incident persons with end stage kidney disease between 2015 and 2020, and who received a kidney transplant during this period were followed-up from their transplantation date to December 31, 2021. The estimated excess risk during the pandemic period was concentrated among KTR with a history of COVID-19 related hospitalization. For those without such history, survival rates during the pre-pandemic and pandemic periods did not significantly differ. Notably, it was not until the third dose of the vaccine that a significant reduction in the risk of death was observed in kidney transplant recipients; The second study in this thesis examined the evolving impact of the pandemic on the management and survival of individuals with end-stage renal disease treated by dialysis, with incident cases between 2015 and 2021, and follow-up until December 31, 2022. The analyses indicated both direct and indirect adverse effects of the pandemic on the probability of dialysis patients receiving a kidney transplant during this period. Excess risk was observed only during epidemic waves and in individuals with a history of hospitalization for COVID-19. No indirect impact of the pandemic on dialysis survival was detected. Receiving booster doses was associated with improved survival. Finally, the estimated risks during the pandemic for dialysis patients and matched controls were similar, suggesting that the risks observed for dialysis patients were more related to their overall health context than to kidney disease.La première étude composant cette thèse a estimé l'impact de la période pandémique sur la survie de transplantés rénaux incidents en France entre 2015 et 2020, et suivis jusqu'au 31/12/2021. Le surrisque estimé durant la période pandémique était concentré chez les transplantés ayant un historique d'hospitalisation pour COVID-19, mais pour ceux sans un tel historique, la survie pendant la période pré-pandémique et pandémique n'était pas significativement différente. De plus, ce n'est qu'à partir de la troisième dose de vaccin que l'on observe une diminution significative du risque de décès chez les transplantés rénaux. La seconde étude composant cette thèse a examiné l'évolution de l'impact de la pandémie sur la prise en charge et la survie des personnes en insuffisance rénale chronique terminale traitée par dialyse, incidentes entre 2015 et 2021, et suivies jusqu'au 31/12/2022. Les analyses indiquent un impact direct et indirect défavorable de la période pandémique sur la probabilité des dialysés de bénéficier d'une greffe de rein pendant cette période. Un surrisque était observé uniquement durant les vagues épidémiques et chez les personnes ayant un historique d'hospitalisation pour COVID-19. Aucun impact indirect de la période pandémique sur la survie des dialysés n'a été détecté. Recevoir des doses de rappel vaccinal était associé à une meilleure survie. Enfin, les risques estimés pendant la période pandémique chez les dialysés et des témoins appariés étaient similaires, les risques des dialysés observés apparaissent donc plus liés à leur santé contextuelle, que reliés à la maladie rénale stricto sensu
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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