1,357,732 research outputs found
Lerche Supplementary file Goldilocks Work planning tool final.xlsx
No full textThe Goldilocks Work planning tool was developed and used in the Goldilocks Work intervention described by Lerche et. al. (2022).
The purpose of the tool was to support workteams when planning and organizing their work tasks towards a 'just right' ergonomic balance of physical behaviors in terms of proportions of time spent sitting, standing and active, and the frequency of alternating between sitting, standing and active work tasks.</p
'Descriptio Plantarum'
No full textFull title: 'Descriptio Plantarum | quarundam | partim minus cognitarum, | Astrachanensium et Provinciarum | Persiae, Mari Caspio adjacentium, | juxta methodum sexualem | Excellentissimi Dni Archiatri | Caroli Linnaei | Accedit | Plantarum Catalogus | istarum Regionum, | com Observationibus | opusculum hoc Botanicum | Collegio Medico Imperiali Rossiaco | offert | Joannes Jacobus Lerche | Petropoli A. 1765.'
Sent with letter from Johann Jacob Lerche to Carl Linnaeus, 18 July 1766 n.s., "The Linnaean correspondence", linnaeus.c18.net, letter L3783.
Set of 2 fascicles bound with red string. Paginated by the author.
Autograph
Comments on Michael Lerche Nielsen’s Paper
No full textA complement to Michael Lerche Nielsen's paper "Runic Inscriptions Reflecting Linguistic Contacts between West Slav Lands and Southern Scandinavia" in the same issue (Scripta Islandica 65), pp. 153–172.</p
Stable nuclear transformation of Eudorina elegans
No full textLerche K, Hallmann A. Stable nuclear transformation of Eudorina elegans. BMC Biotechnology. 2013;13(1): 11.UNLABELLED: ABSTRACT: BACKGROUND: A fundamental step in evolution was the transition from unicellular to differentiated, multicellular organisms. Volvocine algae have been used for several decades as a model lineage to investigate the evolutionary aspects of multicellularity and cellular differentiation. There are two well-studied volvocine species, a unicellular alga (Chlamydomonas reinhardtii) and a multicellular alga with differentiated cell types (Volvox carteri). Species with intermediate characteristics also exist, which blur the boundaries between unicellularity and differentiated multicellularity. These species include the globular alga Eudorina elegans, which is composed of 16-32 cells. However, detailed molecular analyses of E. elegans require genetic manipulation. Unfortunately, genetic engineering has not yet been established for Eudorina, and only limited DNA and/or protein sequence information is available. RESULTS: Here, we describe the stable nuclear transformation of E. elegans by particle bombardment using both a chimeric selectable marker and reporter genes from different heterologous sources. Transgenic algae resistant to paromomycin were achieved using the aminoglycoside 3'-phosphotransferase VIII (aphVIII) gene of Streptomyces rimosus, an actinobacterium, under the control of an artificial promoter consisting of two V. carteri promoters in tandem. Transformants exhibited an increase in resistance to paromomycin by up to 333-fold. Co-transformation with non-selectable plasmids was achieved with a rate of 50 - 100%. The luciferase (gluc) gene from the marine copepod Gaussia princeps, which previously was engineered to match the codon usage of C. reinhardtii, was used as a reporter gene. The expression of gluc was mediated by promoters from C. reinhardtii and V. carteri. Heterologous heat shock promoters induced an increase in luciferase activity (up to 600-fold) at elevated temperatures. Long-term stability and both constitutive and inducible expression of the co-bombarded gluc gene was demonstrated by transcription analysis and bioluminescence assays. CONCLUSIONS: Heterologous flanking sequences, including promoters, work in E. elegans and permit both constitutive and inducible expression of heterologous genes. Stable nuclear transformation of E. elegans is now routine. Thus, we show that genetic engineering of a species is possible even without the resources of endogenous genes and promoters
Evidence for a dynamical halo around the edge-on galaxy NGC 4631
No full textRadio continuum observations at five frequencies between 327 MHz and 10.7 GHz of the edge on galaxy NGC 4631 confirm the prediction concerning the frequency dependence of the halo extent and the spatial variations of the radio spectral indices in the dynamical halo model made by Lerche and Schlickeiser. The measurements are presented, and a detailed comparison with theoretical predictions is made
Impact of Context Information on Metaphor Elaboration: A Diffusion Model Study
No full textProject description and data analyses can be found in:
Lerche, V., Christmann, U., & Voss, A. (in press). Impact of Context Information on Metaphor Elaboration: A Diffusion Model Study. Experimental Psychology. doi: https://doi.org/10.1027/1618-3169/a00042
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
- …
