282 research outputs found
Correction to
Get PDFThe article “Intermittent levosimendan infusion in ambulatory patients with end‑stage heart failure: a systematic review and meta‑analysis of 984 patients”, written by Hagar Elsherbini, Osama Soliman, Casper Zijderhand, Mattie Lenzen, Sanne E. Hoeks, Rasha Kaddoura, Mohamed Izham5, Abdulaziz Alkhulaifi, Amr S. Omar, and Kadir Caliskan, was originally published electronically on the publisher’s internet portal on 11 April 2021 without open access. With the author(s)’ decision to opt for Open Choice the copyright of the article changed on 10 June 2021 to</p
History of Cornelius
Get PDFA clean library copy of the History of Cornelius by Mattie Mann Smith. A picture of the author is included at the end
Transcatheter Aortic Valve Implantation in Older Adults: The role of frailty and vascular aging
Get PDFThe overall aim of this thesis was to better understand the implications of several aspects of age related conditions and processes in TAVI candidates and optimizing care by incorporating frailty in clinical decision making and to improve periprocedural care
Evaluating the Application and Applicability of Treatment Guidelines in Daily Clinical Practice. Closing the loop with the Euro Heart Survey programme
Get PDFThe main research questions in this thesis correspond to those of the Netherlands Heart
Foundation (NHF)-Health Care programme and were closely related to the aims of the Euro
Heart Survey (EHS) programme, namely to evaluate to which extend every day clinical
practice corresponds with evidence-based guidelines and to evaluate the generalisability of
evidence-based treatment.
The EHS is initiated by the European Society of Cardiology (ESC) and recognized by
the Netherlands Heart Foundation, resulting in a combined EHS and Netherlands Heart
Foundation - Health Care programme. Since the start of the EHS programme in 1999, up to
the end of 2006, over 80,000 patients have been included. These surveys provided systematic
information on various groups of patients with cardiovascular diseases. In this thesis we
present the results of three surveys, namely Heart Failure, Coronary Revascularization, and
Diabetes and the Heart.
Our observations in the EHS on Coronary Revascularization showed a clear
preference of percutaneous coronary intervention (PCI) over coronary bypass surgery
(CABG) and pharmacological treatment after coronary angiography in clinical practice
(chapter 2). In line with the guidelines, patients selected for CABG had more extensive
coronary artery disease, and more often co-morbid conditions as compared to patients
undergoing PCI. However, a sizeable proportion of patients with multivessel disease or left
main, heart failure or diabetes did not undergo CABG but underwent PCI or were treated
medically. We identified the under-use of adjunctive pharmacology, including GP IIb/IIIa
inhibitors at time of intervention, statins and ACE-inhibitors as secondary prevention, as main
areas for improvement in patient care. Yet, we confirmed that the recommendations of
guidelines were applied in the majority of patients with proven coronary artery disease who
underwent an invasive coronary procedure.
The comparison of patients with coronary artery disease from clinical practice (EHS
on Coronary Revascularization) with patients who participated in 14 major randomised
controlled trials (RCTs) comparing PCI with CABG revealed that almost two-third of patients
as seen in clinical practice would have been disqualified for trial participation (chapter 3).
Important differences were observed between trial participants and survey patients. Patients
in clinical practice were older, more likely to have co-morbidity and left main stenosis, but less
often multi-vessel disease as compared to trial participants. Although we observed important
differences in clinical characteristics, the outcomes with respect to repeat revascularization and
mortality of patients who underwent PCI or CABG in clinical practice were identical to those
of the RCTs comparing PCI with CABG
Evaluating the application and applicability of treatment guidelines in daily clinical practice
Get PDFEvaluating the application and applicability of treatment guidelines in daily clinical practice
Get PDFEvaluating the application and applicability of treatment guidelines in daily clinical practice
Get PDFWandering through Wonderland : Lewis Carroll\u27s Life as a Logician, Author, and Man of God
Get PDFCharles Dodgson, better known as Lewis Carroll, lived his life as a man of God, a skilled logician, and a masterful author. Much can be learned through a study of his life and his successes. Tracing his early years, his studies, and his accomplishments, while recognizing the accolades and admonitions of his contemporaries, reveals much about the influences on Dodgson’s life. To separate his faith from his work is impossible and speaks to the precedence his beliefs held over all of his other ambitions
True Grit et son héroïne, Mattie Ross : une voix pour les femmes ?
No full textTrue Grit paraît en 1968 aux États-Unis, alors que la contre-culture est à son apogée. Ce western, publié à une époque où les valeurs fondatrices de la société américaine sont fortement remises en question, rencontre un véritable succès. Son auteur, Charles Portis, s’affranchit des codes classiques du western en plaçant Mattie, une adolescente, au cœur de l’intrigue. Dotée des attributs traditionnellement réservés aux héros masculins - force, courage, détermination -, elle incarne également les valeurs morales dont les personnages féminins sont habituellement dépourvus. L’auteur nous offre un western subversif qui interroge la place et le rôle de la femme dans la société américaine. Dans quelle mesure True Grit bouleverse-t-il le statut de la femme ? Cette vision de la femme libre et émancipée se heurte-t-elle a des limites ?True Grit was published in the United States in 1968, at the height of the counterculture movement. This western was a bestseller although the founding values of America were being strongly challenged at the time. The author, Charles Portis, freed himself from the traditional codes of the western genre: his heroine, Mattie, is a teenage girl. Displaying many features usually reserved to male characters (strength, bravery, determination), she also embodies moral values. A subversive western, True Grit questions the role and the position of women in the American society. Does this image of a free woman face some limits
An experiment with the activity program in the T.V.A. schools located at Joe Wheeler Dam, Alabama and Pickwick Dam, Tennessee, 1939
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