883 research outputs found
Novel blood-based biomarkers and disease modifying therapies for Alzheimer's disease. Are we ready for the new era?
No full textRecent positive trials for novel disease modifying therapies of anti-amyloid monoclonal antibodies represent a paradigm shift in the prevention and management of Alzheimer’s disease, a relentlessly progressive and debilitating disease of old age. The reported efficacy of these new agents when given early in the disease trajectory is dependent on an early and accurate disease diagnosis, which is currently
based on cerebrospinal fluid tests or/and neuro-imaging studies such as positron emission tomography. These confirmatory tests provide in vivo evidence of the pathological signature of Alzheimer’s disease, of
increased cerebral amyloid and tau burden and neurodegeneration. The emergence of blood-based
biomarkers represents another breakthrough, offering a less invasive and scalable diagnostic tool that could be applied in both primary and specialist care settings, potentially revolutionizing Alzheimer’s disease clinical pathways. However, healthcare systems face challenges in the adoption of these new technologies and therapies due to diagnostic and treatment capacity constraints, as well as financial and infrastructure requirements
Thomas Middleton and Early Modern Textual Culture A Companion to the Collected Works
No full textThomas Middleton and Early Modern Textual Culture is a comprehensive companion to The Collected Works of Thomas Middleton, providing detailed introductions to and full editorial apparatus for the works themselves as well as a wealth of information about Middleton's historical and literary context. It will be indispensable to scholars of Renaissance literature as well as essential reading for anyone interested in the history of the book in early modern Europe. - ;Thomas Middleton and Early Modern Textual Culture is not only a companion to The Collected Works of Thomas Middleton, which every scholar of Renaissance literature will find indispensable. It is also essential reading for anyone interested in the history of the book in early modern Europe. The book is divided into three parts. The first part, on The Culture, situates Middleton within an historical and theoretical overview of early modern textual production, reproduction, circulation, and reception. An introductory essay by Gary Taylor (The Order of Persons) surveys lists of persons written by or connected to Middleton, using the complex relationship between textual and social orders to trace the evolution of textual culture in England during the Middleton century (1580-1679). Ten. original essays then focus on Middletons connections to different aspects of textual culture in that century: authorship (by MacD. P. Jackson), manuscripts (Harold Love), legal texts (Edward Geiskes), censorship (Richard Burt), printing (Adrian Weiss), visual texts (John Astington), music (Andrew. Sabol), stationers and living authors (Cyndia Clegg), posthumous publishing (Maureen Bell), and early readers (John Jowett). The rest of the volume, supplies the documentation for claims made in the first part. Part II, the author includes detailed evidence for the canon and chronology of Middletons works in allgenres, greatly extending previous scholarship, and using the latest corpus-based attribution techniques. This section situates individual authorial agency in the space between larger institutional forces and the material specificity of particular textual embodiments. Part III, The Texts, contains a full. editorial apparatus for each item in The Collected Works: an Introduction, which summarizes and extends previous scholarship, is followed by textual notes, recording substantive departures from the control-text, variants between early texts, press-variants, discussions of emendations, and (for plays) an. exact transcription of all original stage directions. Cross-references make it easy to move between the two volumes. This authoritative account of the early texts includes some extraordinarily complicated cases, which have never before been systematically collated: Hence, all you vain delights (the most popular song lyric from the Renaissance stage), The Two Gates of Salvation, The Peacemaker, and A Game at Chess (the most complex editorial problem in early modern drama, with eight extant texts and numerous reports of the early performances). - ;...elaborately cross-referenced...a good deal of effort has gone into making the Companion as user-friendly as possibe... - Michael Neill LRB;The Oxford Middleton is a monumental achievement. Gary Taylor and his team of scholars have managed to do for Thomas Middleton what Heminges and Condell did for Shakespeare in the 1623 First Folio: they've collected a great playwright's work in a landmark edition, one that enables us to appreciate afresh an extraordinary literary career. Taken together, The Collected Works of Thomas Middleton and its companion volume Thomas Middleton and Early Modern Textual. Culture, provide an essential guide to matters at the heart of the English literary world in the earlyseventeenth century, from authorship and collaboration to censorship, civic pageantry, and the London book trade. - James Shapiro, author of 1599: A Year in the Life of William Shakespeare and Professor of English, Columbia University;a monumental work of scholarship - Jonathan Bate, Times Literary Supplement;It is not, I think, overstating the case to say that the release of this edition feels epochal, and the sense of recognition at what it has added, as well as what it will inspire over the ensuing decades, is already palpable. The Oxford Middleton is a truly momentous work, and it is now in the hands of you, the Great Variety of Readers. - Will Sharpe, The Shakespeare Bookshop Newsletter;All of us who care deeply about the history of English drama welcome with great enthusiasm and excitement the publication of the Collected Works of Thomas Middleton, a major achievement in textual scholarship that represents the collective expertise and critical wisdom of scholars from all over the world. Gary Taylor and his many collaborators have given us a new and remarkably versatile Thomas Middleton-a great tragic playwright, a brilliant creator of sly and cynical. urban comedies, a thoroughly gifted man of the theater and citizen of London. With this massive collected edition, the history of English drama is much more complete and we can hope for many more professional productions of these neglected plays. - Gail Paster, Director, Folger Shakespeare Library;It is hard to exaggerate the scale of the Oxford Middleton particularly since this is the kind of scholarship which is--in its diversity and eclecticism--designed to open up debate rather than close it off. It is a colossal achievement representing a decisive expansion of Renaissanc studies which will percolate throughout scholarship and teaching. But what is, perhaps, most exciting, is that thecollection must surely generate a rediscovery of these eminently stageable plays in the. theatre. - Andrew James Hartley, Editor, Shakespeare Bulletin;The publication of The Complete Works of Middleton will be a major event for all those who care about the theatre of Shakespeare's time. The scholarship is meticulous, the commentary is fascinating and the international team of experts displays the field of Renaissance Drama studies at its finest. In modern times, productions of The Changeling and Women Beware Women have shown the dark side of sex and power that Shakespeare touched on but never fully explored. The Complete Works now shows us the full range of Middleton's talent for comedy and social drama and, controversially, the full extent of his collaboration with and development of Shakespeare's plays. - Kathleen E. McLuskie, The Shakespeare Institute;Few editorial projects have been as eagerly anticipated as the Oxford Middleton, which will utterly transform how we understand early modern drama, both in the classroom and in our research. As with Shakespeare, Gary Taylor and his team have set a new gold standard for textual editing and interpretive criticism, leaping from the 19th century to the 21st - finally an edition that captures Middleton's tremendous accomplishments. - Henry Turner, Rutgers University, New Jersey, author of The English Renaissance Stage: Geometry, Poetics, and the Practical Spatial Arts, 1580-1630 (Oxford, 2006).Intro -- TABLE OF CONTENTS -- ALPHABETICAL CONTENTS -- INDEX OF TITLES BY GENRE -- LIST OF ILLUSTRATIONS -- HOW TO USE THIS BOOK -- PREFACE: TEXTUAL PROXIMITIES -- Part I: The Culture -- 'The Order of Persons' -- 'Early Modern Authorship: Canons and Chronologies' -- 'Thomas Middleton: Oral Culture and the Manuscript Economy' -- From Wronger and Wronged Have I Fee": Thomas Middleton and Early Modern Legal Culture -- 'Middleton, Music, and Dance' -- 'Thomas Middleton, Uncut: Castration, Censorship, and the Regulation of Dramatic Discourse in Early Modern England' -- 'Casting Compositors, Foul Cases, and Skeletons: Printing in Middleton's Age' -- 'Visual Texts: Thomas Middleton and Prints' -- Twill Much Enrich the Company of Stationers": Thomas Middleton and the London Book Trade, 1580-1627 -- 'Booksellers without an Author, 1627-1685' -- 'For Many of Your Companies: Middleton's Early Readers' -- Part II: The Author -- 'Introduction: The Middleton Canon' -- 'Works Included in this Edition: Canon and Chronology' -- 'Works Excluded from this Edition' -- Part III: The Texts -- 'Thomas Middleton: Lives and Afterlives -- 'Middleton's London -- 'Middleton's Theatres -- The Wisdom of Solomon Paraphrased -- Microcynicon: Six Snarling Satires -- The Ghost of Lucrece -- The Penniless Parliament of Threadbare Poets -- News from Gravesend -- The Nightingale and the Ant -- and, Father Hubburd's Tales -- The Meeting of Gallants at an Ordinary -- Plato's Cap -- The Black Book -- The Whole Royal and Magnificent Entertainment -- The Patient Man and the Honest Whore -- The Phoenix -- Michaelmas Term -- The Puritan Widow -- or, The Puritan -- or, The Widow of Watling Street -- The Revenger's Tragedy -- A Trick to Catch the Old One -- Your Five Gallants -- A Mad World, My Masters -- A Yorkshire Tragedy -- Sir Robert Sherley -- The Two Gates of SalvationThe Roaring Girl -- The Lady's Tragedy -- The Triumphs of Truth -- The Manner of his Lordship's Entertainment -- Masque of Cupids -- Civitatis Amor -- A Fair Quarrel -- The Owl's Almanac -- The Triumphs of Honour and Industry -- Orazio Busino's Eyewitness Account of The Triumphs of Honour and Industry -- Masque of Heroes -- or, The Inner Temple Masque -- The Peacemaker -- or, Great Britain's Blessing -- The World Tossed at Tennis -- The Triumphs of Love and Antiquity -- Honourable Entertainments -- The Sun in Aries -- An Invention -- The Triumphs of Honour and Virtue -- The Triumphs of Integrity -- The Triumphs of the Golden Fleece -- Measure for Measure: A Genetic Text -- The Tragedy of Macbeth: A Genetic Text -- The Life of Timon of Athens -- A Game at Chess: General Textual Introduction -- A Game at Chesse: An Early Form -- A Game at Chess: A Later Form -- Occasional Poems -- The Witch -- The Triumphs of Health and Prosperity -- A Chaste Maid in Cheapside -- The Bloody Banquet -- Hengist, King of Kent -- or, The Mayor of Queenborough -- Wit at Several Weapons -- The Nice Valour -- or, The Passionate Madman -- The Widow -- The Changeling -- The Spanish Gypsy -- Lost Plays -- An/The Old Law -- More Dissemblers Besides Women -- Women, Beware Women -- No Wit/Help like a Woman's -- Anything for a Quiet Life -- Lost Political Prose, 1620-7: A Brief Account -- INDEX TO NOTES ON MODERNIZATION -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- Y -- Z -- A SELECTIVE TOPICAL INDEX -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- R -- S -- T -- U -- V -- WThomas Middleton and Early Modern Textual Culture is a comprehensive companion to The Collected Works of Thomas Middleton, providing detailed introductions to and full editorial apparatus for the works themselves as well as a wealth of information about Middleton's historical and literary context. It will be indispensable to scholars of Renaissance literature as well as essential reading for anyone interested in the history of the book in early modern Europe. - ;Thomas Middleton and Early Modern Textual Culture is not only a companion to The Collected Works of Thomas Middleton, which every scholar of Renaissance literature will find indispensable. It is also essential reading for anyone interested in the history of the book in early modern Europe. The book is divided into three parts. The first part, on The Culture, situates Middleton within an historical and theoretical overview of early modern textual production, reproduction, circulation, and reception. An introductory essay by Gary Taylor (The Order of Persons) surveys lists of persons written by or connected to Middleton, using the complex relationship between textual and social orders to trace the evolution of textual culture in England during the Middleton century (1580-1679). Ten. original essays then focus on Middletons connections to different aspects of textual culture in that century: authorship (by MacD. P. Jackson), manuscripts (Harold Love), legal texts (Edward Geiskes), censorship (Richard Burt), printing (Adrian Weiss), visual texts (John Astington), music (Andrew. Sabol), stationers and living authors (Cyndia Clegg), posthumous publishing (Maureen Bell), and early readers (John Jowett). The rest of the volume, supplies the documentation for claims made in the first part. Part II, the author includes detailed evidence for the canon and chronology of Middletons works in allgenres, greatly extending previous scholarship, and using the latest corpus-based attribution techniques. This section situates individual authorial agency in the space between larger institutional forces and the material specificity of particular textual embodiments. Part III, The Texts, contains a full. editorial apparatus for each item in The Collected Works: an Introduction, which summarizes and extends previous scholarship, is followed by textual notes, recording substantive departures from the control-text, variants between early texts, press-variants, discussions of emendations, and (for plays) an. exact transcription of all original stage directions. Cross-references make it easy to move between the two volumes. This authoritative account of the early texts includes some extraordinarily complicated cases, which have never before been systematically collated: Hence, all you vain delights (the most popular song lyric from the Renaissance stage), The Two Gates of Salvation, The Peacemaker, and A Game at Chess (the most complex editorial problem in early modern drama, with eight extant texts and numerous reports of the early performances). - ;...elaborately cross-referenced...a good deal of effort has gone into making the Companion as user-friendly as possibe... - Michael Neill LRB;The Oxford Middleton is a monumental achievement. Gary Taylor and his team of scholars have managed to do for Thomas Middleton what Heminges and Condell did for Shakespeare in the 1623 First Folio: they've collected a great playwright's work in a landmark edition, one that enables us to appreciate afresh an extraordinary literary career. Taken together, The Collected Works of Thomas Middleton and its companion volume Thomas Middleton and Early Modern Textual. Culture, provide an essential guide to matters at the heart of the English literary world in the earlyseventeenth century, from authorship and collaboration to censorship, civic pageantry, and the London book trade. - James Shapiro, author of 1599: A Year in the Life of William Shakespeare and Professor of English, Columbia University;a monumental work of scholarship - Jonathan Bate, Times Literary Supplement;It is not, I think, overstating the case to say that the release of this edition feels epochal, and the sense of recognition at what it has added, as well as what it will inspire over the ensuing decades, is already palpable. The Oxford Middleton is a truly momentous work, and it is now in the hands of you, the Great Variety of Readers. - Will Sharpe, The Shakespeare Bookshop Newsletter;All of us who care deeply about the history of English drama welcome with great enthusiasm and excitement the publication of the Collected Works of Thomas Middleton, a major achievement in textual scholarship that represents the collective expertise and critical wisdom of scholars from all over the world. Gary Taylor and his many collaborators have given us a new and remarkably versatile Thomas Middleton-a great tragic playwright, a brilliant creator of sly and cynical. urban comedies, a thoroughly gifted man of the theater and citizen of London. With this massive collected edition, the history of English drama is much more complete and we can hope for many more professional productions of these neglected plays. - Gail Paster, Director, Folger Shakespeare Library;It is hard to exaggerate the scale of the Oxford Middleton particularly since this is the kind of scholarship which is--in its diversity and eclecticism--designed to open up debate rather than close it off. It is a colossal achievement representing a decisive expansion of Renaissanc studies which will percolate throughout scholarship and teaching. But what is, perhaps, most exciting, is that thecollection must surely generate a rediscovery of these eminently stageable plays in the. theatre. - Andrew James Hartley, Editor, Shakespeare Bulletin;The publication of The Complete Works of Middleton will be a major event for all those who care about the theatre of Shakespeare's time. The scholarship is meticulous, the commentary is fascinating and the international team of experts displays the field of Renaissance Drama studies at its finest. In modern times, productions of The Changeling and Women Beware Women have shown the dark side of sex and power that Shakespeare touched on but never fully explored. The Complete Works now shows us the full range of Middleton's talent for comedy and social drama and, controversially, the full extent of his collaboration with and development of Shakespeare's plays. - Kathleen E. McLuskie, The Shakespeare Institute;Few editorial projects have been as eagerly anticipated as the Oxford Middleton, which will utterly transform how we understand early modern drama, both in the classroom and in our research. As with Shakespeare, Gary Taylor and his team have set a new gold standard for textual editing and interpretive criticism, leaping from the 19th century to the 21st - finally an edition that captures Middleton's tremendous accomplishments. - Henry Turner, Rutgers University, New Jersey, author of The English Renaissance Stage: Geometry, Poetics, and the Practical Spatial Arts, 1580-1630 (Oxford, 2006).Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
David Fable Books No 1
No full textThere are five stories in this book. I ordered this one for the collection because of the title of the first: The Story of Anna, Buddy, and the Country Mouse. That story is utterly charming, together with its colored lithographs. The author frequently pauses to note to the reader elements of a picture that the reader might miss. There is a first visit to a town, complete with a visit to a restaurant for tea, but in this case the two dogs sit nicely at a table and order, while Homer the mouse gets on top of the table. The three then again travel by bus back to the country. The five stories are interspersed with illustrations for traditional rhymes, including Sing a Song of Sixpence. Indeed, it is the art that makes this book, along with the charm of whimsical local stories. Coppin was serving in the armed forces overseas during World War II and wrote these stories for his son David, to whom the book is dedicated. There is a picture of David facing the Publisher's Introduction at the book's beginning.This is a hardbound book (hard cover)Alan Middleton Coppi
Exploring functional connectivity patterns and their associations with amyloid and tau biomarkers across alzheimer's disease stages: a resting-state fmri study
No full textBackground: Alzheimer's disease (AD) is a progressive neurodegenerative disorder marked by cognitive decline and hallmark biomarkers: amyloid-beta (Aβ) plaques and neurofibrillary tau tangles. Functional connectivity, assessed via resting-state functional Magnetic Resonance Imaging (fMRI), has shown associations with Aβ and tau. However, its adoption is hindered by high data dimensionality, noise, and artefact susceptibility.
This study explored functional connectivity differences across clinically relevant AD groups, aiming to enhance our understanding of the link between brain function and AD neuropathology.
Methods and Data Analysis: Two datasets were used for cross-sectional analyses: dataset 1 was comprised of cognitively unimpaired (CU), mild cognitive impairment (MCI), and dementia of the Alzheimer’s Disease type (DAT) participants. Dataset 2 included CU only. Whole-brain region-of-interest (ROI)-to-ROI analysis was followed by a dual-approach of Multivariate Pattern Analysis and seed-based connectivity to identify regions and measure group differences in functional connectivity patterns. We then investigated whether AD biomarkers moderate functional connectivity and cognition relationships.
Lastly, network-level functional connectivity differences within and between the Default Mode network and medial temporal lobe (MTL) were measured between CU Aβ+ and Aβ- participants.
Results: Multivariate Pattern Analysis revealed functional connectivity differences between two out of three group comparisons. The left thalamus, precuneus, and frontal gyri sub-regions were identified as key ROIs. Tau (more than Aβ) moderated more relationships between functional connectivity and cognition, particularly among MCI participants.
In dataset 2, CU Aβ+ participants showed more relationships between MTL functional connectivity and regional tau burden. Specifically, among Aβ+, lower functional connectivity was associated with higher tau pathology, pointing towards early neurodegeneration.
Conclusions: These findings enhance our understanding of the interplay between brain function and AD pathology, reinforce tau as a biomarker closely linked to functional connectivity, and identify specific brain regions and networks with potential clinical applications in early AD diagnosis and therapeutic interventions.Open Acces
Middleton and Rowley: Forms of Collaboration in the Jacobean Playhouse
No full textThis review considers Middleton & Rowley: Forms of Collaboration in the Jacobean Playhouse
Correction for Prusiner et al., Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
No full textCorrection for “Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism,” by Stanley B. Prusiner, Amanda L. Woerman, Daniel A. Mordes, Joel C. Watts, Ryan Rampersaud, David B. Berry, Smita Patel, Abby Oehler, Jennifer K. Lowe, Stephanie N. Kravitz, Daniel H. Geschwind, David V. Glidden, Glenda M. Halliday, Lefkos T. Middleton, Steve M. Gentleman, Lea T. Grinberg, and Kurt Giles, which was first published August 31, 2015; 10.1073/pnas.1514475112 (Proc. Natl. Acad. Sci. U.S.A. 112, E5308–E5317).
The authors note that Fig. 3 appeared incorrectly. The corrected figure and its legend appear below. The online version has been corrected
Ethnicity, cardiovascular disease & the risk of Alzheimer’s disease and related dementias (ADRD)
No full textBackground: It is widely known that South Asian and Black minority ethnic groups, in the United Kingdom, have a higher incidence and prevalence of cardiovascular disease and it is thought that this may in turn place these ethnic groups at a greater risk of developing dementia than the White ethnic groups. This study seeks to explore this theory further, using large scale population-based databases, in the United Kingdom.
Methods: All eligible participants over the age of 50 years from the CPRD database, that were free from a diagnosis of dementia at time of entry to the study, those with an ethnic coding were stratified into 5 different ethnic groups, White, Black, South Asian, East Asian and Mixed. Their trajectories were followed over the observation period from 1996 to the end of the study (2016). Cardiovascular Disease (CVD) and available lifestyle risk factor data relating to the development of dementia were also recorded over this period.
Results: A total of 1,091,242 individuals were included in the analytical sample, after exclusion of those with missing ethnicity data. There were a total of 174,546 (16.3%) cases of ascertained dementia. The white ethnic group had a higher mean age of dementia onset 81.8 years (SD 8.6) just ahead of the East Asian 80.3 years (8.9) ethnic group and the lowest mean age of onset seen in the Black ethnic group 76.3 years (SD 9.4). The fully adjusted Cox regression model (adjusting for all covariates including, socioeconomic status and education) revealed a lower risk of incident dementia in the Black [HR 0.83 (95% CI 0.74-0.93)] and South Asian ethnic groups [HR 0.55 (95% CI 0.49-0.61)], and the excessive risk in East Asian ethnic group was no longer found to be significant [HR 1.14 (95% CI 0.93-1.42)]. The East Asian ethnic group had a higher cumulative incidence of dementia than any other ethnic group when accounting for death as a competing risk [sdHR 1.37, (95% CI 1.18-1.58 for East Asian compared to White ethnicity]. However, overall cumulative incidence rates of dementia did not significantly change between the other ethnic groups when accounting for death as a competing risk.
Conclusion: The lower incidence of dementia seen in the Black and South Asian groups is intriguing and may be due to case under ascertainment amongst these ethnic groups, in view of their higher risk of cardiovascular disease. Understanding the differences for ethnic variation in dementia rates is not only vital for aetiological research but also for the development of prevention strategies, health service planning and resource allocation.Open Acces
Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project)
No full textCopyright © 2004 Excerpta Medica Inc. All rights reserved.Diego F. Wyszynski, Dawn M. Waterworth, Philip J. Barter, Jonathan Cohen, Y. Antero Kesäniemi, Robert W. Mahley, Ruth McPherson, Gérard Waeber, Thomas P. Bersot, Sanjay S. Sharma, Vikki Nolan, Lefkos T. Middleton, Scott S. Sundseth, Lindsay A. Farrer, Vincent Mooser, Scott M. Grund
Changing patterns in vocational education
No full textOne of the long standing issues in education development has been productive job training in rapidly changing economies. The argument has been made that vocational secondary schools are not well equipped for this task. Although vocational and academic schooling often result in similar levels of education and employment, the higher costs of the vocational schooling makes it a less attractive alternative. In the past 23 years of Bank lending for vocational education and training, there has been a clear shift away from vocational secondary schools toward various forms of training, outside the formal education system. Although investment has been shifting into nonformal training, secondary education is in need of new directions. Diversified secondary schools have not provided that direction, leaving questions about how secondary schools might meet social objectives cost effectively.Tertiary Education,Teaching and Learning,Gender and Education,Primary Education,Curriculum&Instruction
Thomas Middleton and the Plural Politics of Jacobean Drama
No full textThomas Middleton and the Plural Politics of Jacobean Drama represents the first sustained study of Middleton\u27s dramatic works as responses to James I\u27s governance. Through examining Middleton’s poiesis in relation to the political theology of Jacobean London, Kaethler explores early forms of free speech, namely parrhēsia, and rhetorical devices, such as irony and allegory, to elucidate the ways in which Middleton’s plural art exposes the limitations of the monarch’s sovereign image. By drawing upon earlier forms of dramatic intervention, James’s writings, and popular literature that blossomed during the Jacobean period, including news pamphlets, the book surveys a selection of Middleton\u27s writings, ranging from his first extant play The Phoenix (1604) to his scandalous finale A Game at Chess (1624). In the course of this investigation, the author identifies that although Middleton’s drama spurs political awareness and questions authority, it nevertheless simultaneously promotes alternative structures of power, which manifest as misogyny and white supremacy.https://scholarworks.wmich.edu/mip_ltsd/1005/thumbnail.jp
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