1,721,012 research outputs found

    XXII International Conference on Mechanics in Medicine and Biology - Abstracts Book

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    This book contain the abstracts presented the XXII ICMMB, held in Bologna in September 2022. The abstracts are divided following the sessions scheduled during the conference

    Implantable Sensors for Cardiac Function Monitoring

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    As heart diseases represent the leading causes of death in the world and the rapidly aging population tends to increase the prevalence of these pathologies, implantable sensors for the continuous monitoring of cardiac function are receiving considerable interest and investment. This article provides an overview of important aspects and challenges dealing with implantable sensor systems for cardiac function monitoring, and it discusses past and recent developments in this area. Part one is a general introduction on design principles for the development of implantable systems, including considerations about the human body's interaction with the implanted device; the appropriate choice of materials, coatings, and packaging techniques (biocompatibility/biostability); and concerns about miniaturization and low-power consumption requirements. Subsequent sections discuss various applications of implantable sensors for cardiac function monitoring, starting from the initial experience of rate-responsive sensors for cardiac pacing up to focus on sensors, most intensely investigated in the last decade, for monitoring cardiac function alterations secondary to heart failure. A final section is provided about future directions and emerging technologies on implantable sensors for cardiovascular applications. The major challenge for the fulfillment of a successful implantable sensor for cardiac function monitoring deals with demonstrating its clinical effectiveness, along with ensuring its long-term stability and reliability. To date, many sensors have been investigated, but few of them truly meet these goals and demonstrate their appropriate clinical roles

    3D Virtual Modeling for Morphological Characterization of Pituitary Tumors: Preliminary Results on Its Predictive Role in Tumor Resection Rate

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    Among potential factors affecting the surgical resection in pituitary tumors, the role of tumor three-dimensional (3D) features is still unexplored. The aim of this study is to introduce the use of 3D virtual modeling for geometrical and morphological characterization of pituitary tumors and to evaluate its role as a predictor of total tumor removal. A total of 75 patients operated for a pituitary tumor have been retrospectively reviewed. Starting from patient imaging, a 3D tumor model was reconstructed, and 3D characterization based on tumor volume (Vol), area, sphericity (Spher), and convexity (Conv) was provided. The extent of tumor removal was then evaluated at post-operative imaging. Mean values were obtained for Vol (9117 ± 8423 mm3), area (2352 ± 1571 mm2), Spher (0.86 ± 0.08), and Conv (0.88 ± 0.08). Total tumor removal was achieved in 57 (75%) cases. The standard prognostic Knosp grade, Vol, and Conv were found to be independent factors, significantly predicting the extent of tumor removal. Total tumor resection correlated with lower Knosp grades (p = 0.032) and smaller Vol (p = 0.015). Conversely, tumors with a more irregular shape (low Conv) have an increased chance of incomplete tumor removal (p = 0.022). 3D geometrical and morphological features represent significant independent prognostic factors for pituitary tumor resection, and they should be considered in pre-operative planning to allow a more accurate decision-making process

    Augmented Reality-Assisted Periosteum Pedicled Flap Harvesting for Head and Neck Reconstruction: An Anatomical and Clinical Viability Study of a Galeo-Pericranial Flap

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    Head and neck reconstructive surgeons have recently explored new perspectives in bone restoration using periosteum carrier flaps. Following this idea, we explored the possibility of harvesting a galeo-pericranial flap. The present work studies the vascular supply of the pericranial temporo-parietal region in order to assess the possibility of harvesting a galeo-pericranial flap based on the superficial temporalis vascularization. Anatomical dissections were performed at the Anatomical Institute of the University of Bologna on eight donor cadavers. Then we performed the harvesting of the flap in vivo on eight patients. We introduced augmented reality (AR) to facilitate anatomical visualisation during free flap harvesting. Augmented reality merges virtual and actual objects, allowing direct observation of patient anatomy and the surgical field. No post-operative major or minor complications occurred. We encountered no post-operative functional issues on the donor or recipient sites, and good clinical healing was observed in all patients. In conclusion, we believe that the galea-pericranium flap could represent a new donor site for the harvesting of a periosteum carrier flap

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Pediatric vs adult dosimetry in CBCT: a challenge?

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    Concern about the radiation dose to children from diagnostic radiology examinations has recently been popularly expressed, particularly as related Computed Tomography (CT) procedures. This involves the idea that children can receive higher doses compared to adults. Since the dosimetric quantities are essentially defined for adult patients, if related to effective dose, it becomes important to study and derive methods applicable also to pediatric cases. In fact, the “commonly” statement implies that size, shape, and data for pediatric organs will be derived from adult ones, numerically reducing dosimetric problems to the definition of scaling algorithms. The aim of this study is to analyze the differences in pediatric vs adult dosimetry, starting from measured organ doses in Cone-Beam Computed Tomography (CBCT) procedures for maxilla-facial region. Two different anthropomorphic phantoms (child vs adult phantoms) were scanned, acquiring all data: results will be presented in terms of organ and derived doses, discussing the approach and differences

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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