53 research outputs found
CREDIT RISK AND INTER-FIRM DEPENDENCE
No full textRights Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author
Breast cancer metastasis to the stomach
No full textAim: This study focuses on the stomach as an unusual but not rare site of metastasis of breast cancer.
Methods: We performed a literature search on gastric metastasis from breast cancer searching for reviews from
2000 to 2018 and case reports from 2013 to 2018. We found 11 reviews and 36 case reports and we compared their
findings about important aspects of gastric metastasis, such as disease free survival, overall survival, symptoms,
endoscopic findings, therapy, histology, and immunohistochemistry.
Results: The incidence of stomach as site of metastasis of breast cancer ranges from 5% to 18%. Reviews and
case reports reached similar conclusions about several of the aforementioned aspects: invasive lobular breast
cancer (ILC) is mainly responsible for gastric metastases; disease free survival can vary greatly ranging from 0.5
months to 30 years; gastric metastases usually present with non-specific symptoms, even though five patients in
case reports were asymptomatic; linitis plastica is the most common endoscopic finding; immunohistochemistry
is essential for differentiating primary gastric cancer from metastasis; the preferred treatment is systemic therapy,
but surgery is still an option in case of emergency; median overall survival of patients with gastric metastasis from
breast cancer is 24 months.
Conclusion: Breast metastasis to the stomach should be considered in any patient suspecting gastric neoplasm
previously treated for breast carcinoma, especially if the treated carcinoma was ILC.
Keywords: Gastric metastasis, breast cancer, immunohistochemistry, stomac
Laura Kropff, Pilar Pérez, Lorena Cañaqueo y Julieta Wallace (compiladoras) (2019). La tierra de los otros, la dimensión territorial del genocidio indígena en Río Negro y sus efectos en el presente. Viedma: Universidad Nacional de Río Negro. ISBN 978-987-4960-12-2, 298 páginas.
No full textReseña a Laura Kropff, Pilar Pérez, Lorena Cañaqueo y Julieta Wallace (compiladoras) (2019). La tierra de los otros, la dimensión territorial del genocidio indígena en Río Negro y sus efectos en el presente. Viedma: Universidad Nacional de Río Negro. ISBN 978-987-4960-12-2, 298 páginas
Movimientos sociales y derechos sociales
No full textEste capítulo se ocupa del vínculo entre los movimientos sociales y el activismo legal en el ámbito de los derechos humanos en general y los derechos sociales en particular. Comenzando con una reseña teórica e histórica sobre los movimientos sociales y su relación con el derecho en la Argentina, el texto demuestra la importancia de entender este proceso para dar cuenta de la conformación de un corpus de derechos sociales en el derecho argentino. El capítulo revela, además, las tensiones que han surgido en la literatura sobre movimientos sociales y activismo legal en torno a dos problemas: en qué medida la adopción del marco conceptual de los derechos humanos y de estrategias jurídicas ha sido productiva para la acción y las reivindicaciones de los movimientos sociales y, en segundo lugar, la focalización exclusiva en el análisis de las cortes, lalectura y examen de casos jurídicos oficiales y el accionar de las élites jurídicas. La tesis propuesta sostiene que la relación entre movimientos sociales, militantes, abogados/as y derecho despierta interrogantes que podrían ser, asimismo, objeto de investigación jurídica. Así, proponen una ampliación de la mirada en torno a los movimientos sociales y el derecho haciendo foco en su organización interna, las tensiones entre la perspectiva territorial y profesional, y las diferencias entre movimientos y organizaciones, entre otras.Fil: Cardella, Paula. Universidad de Buenos Aires. Facultad de Derecho; ArgentinaFil: Fernández Meijide, Camila. Universidad de Buenos Aires. Facultad de Derecho. Instituto de Investigaciones Jurídicas y Sociales "Dr. Ambrosio L. Gioja"; ArgentinaFil: Aldao, Martin Maria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Derecho. Instituto de Investigaciones Jurídicas y Sociales "Dr. Ambrosio L. Gioja"; Argentin
Disruptive Innovation and Firm Investment
No full textRecent literature shows that disruption resulting from innovation within an industry negatively impacts incumbent firms. Using a measure based on the scale and intensity of fund raising by venture capital-backed (VC-backed) companies, I study how incumbent firms respond to disruption risk posed by new entrants. My results indicate that when uncertainty regarding within-industry innovation is high, firms significantly increase capital expenditure, and acquisitions. Consistent with my hypotheses, cross-sectional analyses reveal that responses vary with the magnitude of the risk, financial constraints, and the incumbent firm’s competitive position. Additionally, in the presence of potential disruptors who are also unicorns, public firms aggressively invest in acquisition and raise external financing.Embargo status: Restricted until 06/2173. To request the author grant access, click
on the PDF link to the left
Desde el arcón familiar Conferencia inédita de la anarquista Juana Rouco Buela
No full textThe conference that we transcribe here arrived at CeDInCI as a roll of more than twenty handwritten pages neatly tied with a gift ribbon. Rut Akselman Cardella left it in my hands, after a first interview that multiplied into several friendly meetings. She is, in addition to being a biologist and a talented textile artist, granddaughter of the anarchist Juana Rouco Buela.La conferencia que aquí transcribimos llegó al CeDInCI como un rollo de más de veinte páginas manuscritas y prolijamente atadas con una cinta de regalo. La dejó en mis manos Rut Akselman Cardella, tras una primera entrevista que se multiplicó en varios encuentros amistosos. Ella es, además de bióloga y una artista textil talentosa, nieta de la anarquista Juana Rouco Buela
Positive reframing, executive function, and adverse childhood experiences in relation to internalizing symptoms
No full textPositive reframing (PR), or reappraising inaccurate or unhelpful thoughts to be more positive, is frequently utilized in therapy for internalizing disorders. There is increasing support for internalizing symptoms relating to PR as well as executive functioning (EF), including working memory updating, but few studies examine how these variables relate. Further, adverse childhood experiences (ACEs) serve as risk factors for internalizing symptoms, and the relation between PR and internalizing symptoms may function uniquely in adults with ACEs. This study explored multiple mediation models to examine a broad range of self-reported EFs as well as performance-based tasks measuring working memory updating in relation to PR and internalizing symptoms. Further, this study examined ACEs as a potential moderator to provide insight into how PR relates to internalizing symptoms in adults with differing levels of ACEs.
The current study collected self-reported ACEs, frequency of PR, and EF as well as performance-based working memory updating task data from 413 Texas Tech University students. As hypothesized, the relation between self-reported EF and internalizing symptoms was mediated by PR, suggesting PR may be a mechanism of change in this relation. Although additional models were explored, this mediation model had the most support and remained significant when controlling for subjective social status. However, PR was not found to mediate the relation between the performance-based measure of EF and internalizing symptoms. Further, contrary to predictions, the relation between PR and internalizing symptoms did not change at different levels of ACEs. Overall, the current study suggests PR may be an important mechanism of change in the relation between EF and internalizing symptoms.Embargo status: Restricted until 09/2027. To request the author grant access, click on the PDF link to the left
Information, liquidity, and high frequency trading
No full textIn my first essay, we examine the effects of investor disagreement on price discovery using a recurring public information event in the highly liquid crude oil futures market, a market free of short-sale constraints. We show that prices reflect positive news within one-half second of trading, but continue to drift for five minutes when news is negative. Evidence suggests the drift arises from a systematic surge in buying pressure that impedes the price discovery process when news is negative. Our results are consistent with price drift arising from differences in investment horizon, where traders taking long positions condition trades on information beyond the news.
In the second essay, using intraday trading activity for S&P 500 stocks, we find evidence of trade clustering in the first second of trading at discrete time nodes (10:00, 10:30, etc.). These unusual volume spikes are pervasive, varying in magnitude across both the cross-section and time-series. Regression results show that news, order imbalance, and stock characteristics do not fully explain this variation. We explore using these spikes to construct a proxy for cross-sectional variation in HFT activity. Empirical tests suggest that this daily measure (which can be computed across a broad range of stocks) captures a dimension of daily HFT activity related to liquidity provision
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