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Carbon dioxide therapy in the treatment of localized adiposities: clinical study and histopathological correlations
No full textAesthetic Plast Surg. 2001 May-Jun;25(3):170-4.
Carbon dioxide therapy in the treatment of localized adiposities: clinical study and histopathological correlations.
Brandi C, D'Aniello C, Grimaldi L, Bosi B, Dei I, Lattarulo P, Alessandrini C.
Source
Unità Operativa di Chirurgia Plastica, Università digli Studi di Siena, Policlinico Le Scotte, Italy. [email protected]
Abstract
The authors report their experience using carbon dioxide (CO2) therapy for the treatment of 48 female patients presenting adipose accumulations, located on the thighs, knees, and/or abdomen; a Carbomed Programmable Automatic Carbon Dioxide Therapy apparatus was used. In light of the effects of CO2 on the microcirculation recently described in the literature, we expected this gas, which we administered subcutaneously, to positively affect the physiological oxidative lipolytic process. The aim of our study was to evaluate the effect of this therapy on localized adiposities. As such, we describe the method we used and report the results observed in the areas treated (in terms of reduction in maximum circumference) as well as side effects. Furthermore, we assessed the effect of subcutaneous administration of CO2 on the microcirculation by showing changes in the Laser Doppler signal and in the concentration of transcutaneous oxygen tension (tcPO2). Pre- and posttreatment biopsies of tissues were performed in seven patients in order to study the changes induced by the use of CO2 on both adipose and connective tissues. All data obtained were statistically analyzed; values of P < 0.05 were considered significan
Car Stickiness: Heuristics and Biases in Travel Choice
No full textWe conduct a laboratory experiment to investigate the factors determining travel mode choice. Two different scenarios are considered. In the first scenario, subjects have to decide whether to commute by car or by metro. Metro costs are fixed, while car costs are uncertain and determined by the joint effect of casual events and traffic congestion. In the second scenario, subjects have to decide whether to travel by car or by bus, whose costs are determined by a different combination of chance and traffic congestion. Subjects receive feedback information on the actual travel times of both modes. We find that individuals show a marked preference for cars, are inclined to confirm their first choice and exhibit travel mode stickiness. We conclude that travel mode choice is subject to cognitive heuristics and biases leading to robust deviations from rational behaviour
The role of carbon dioxide therapy in Symmetric Multiple Lipomatosis therapeutic strategy
No full textSymmetric Multiple Lipomatosis (LMS) is a rare pathology characterized by the progressive accumulation of noncapsulated adipose masses that tend to flow into and invade adjacent structures: symmetrically in the neck, shoulders and torso and proximally in the extremities. The authors describe a familial form, whose transmission mechanism is unknown, and a sporadic form, frequently related to alcohol abuse. Numerous problems for the treatment of LMS are posed by lack of knowledge on this pathology's biochemical mechanism and the characteristics of the adipose deposits related to the structure of the fat, the close relationship established with nearby structures (further aggravated by the remarkable size of these deposits) and the tendency to recur. In the absence of an etiological therapy, the only currently available form of palliation, in conjunction with a diet and total exclusion of alcohol consumption, is surgery, with or without associated liposuction. The authors report their experience in the adoption of carbon dioxide therapy, associated with surgery, in the treatment of two patients presenting fat deposits variously located in the thighs, arms and abdomen. Expectations that the carbon dioxide (administered subcutaneously) would effectively increase the physiological oxidative lypolytic process were based on recent reports in the literature regarding the effects exerted by this gas on the microcirculatory system. The aim of our work was to study the effects of this therapy and verify its efficacy in reducing adipose accumulations, with a view to demonstrating its potential role in LMS therapeutic strategy
“Smart specialisation”: le sfide del nuovo ciclo di programmazione comunitaria per il regionalismo italiano
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
LE REGIONI D’EUROPA TRA IDENTITÀ LOCALI, NUOVE COMUNITÀ E DISPARITÀ TERRITORIAL
Full text linkEurope today is crossed by a strong demand for autonomy from the territories: on the one hand, to protect the identities of local communities and, on the other, for the growing demand for a wider representation of resident citizens. However, these requests can jeopardize the objectives of balance and integration between parts of the territory and between those who live in them, objectives that have always been at the center of reflection and proposals developed in the context of regional sciences. The recent crisis has heightened instability and widened economic and social gaps not only between regions, but also within the regions themselves. The North-South gaps in Italy have further increased and, in a post-crisis phase, this unstoppable process requires ever greater scientific and policy insights in terms of commitment and intervention capacity. If the economic growth of the past decade had found impetus in expanding the spaces of relationships and exchanges, the responses to the threats brought about by the crisis materialized in the closure of borders and in the defense of local levels of well-being. A particular specification of this theme also concerns the relationships between urban and rural territories and local systems, between plains and mountains as well as mountain areas, .
The preface is therefore an acute reflection on issues of urgent relevance for Italy and of great interest for the regional sciences, accepting important scientific and policy challenges
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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