157 research outputs found
Correction for Melo et al., Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing
No full textMedical sciences: correction for "Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing," by SoniaMelo, Alberto Villanueva, Catia Moutinho, Veronica Davalos, Riccardo Spizzo, Cristina Ivan, Simona Rossi, Fernando Setien, Oriol Casanovas, Laia Simo-Riudalbas, Javier Carmona, Jordi Carrere, August Vidal, Alvaro Aytes, Sara Puertas, Santiago Ropero, Raghu Kalluri, Carlo M. Croce, George A. Calin, and Manel Esteller, which appeared in issue 11, March 15, 2011, of Proc Natl Acad Sci USA (108:4394-4399; first published February 28, 2011; 10.1073/pnas.1014720108)
L’expressió de la violència en la narrativa d’Isabel-Clara Simó
No full textLa nostra recerca se centra en l’anàlisi de contes d’Isabel-Clara Simó. Tot i que la major part de la seua obra narrativa es basa en els paràmetres de la literatura psicològica, la recerca de l’expressió de la solitud dels personatges enmig de les dificultats del seu entorn ens ofereix una tensió íntima dins d’un ampli àmbit de situacions. Com a norma general, Isabel-Clara Simó centra els seus relats sobretot en la denúncia de situacions d’opressió de les dones. En el seu llibre, La salvatge (1994) i Dones (1999), l’autora introdueix la imatge de les dones urbanes actuals on són representades com a víctimes de les seues parelles.Our research focuses on the analysis of short stories by Isabel-Clara Simó. Although most of her narrative work is based on the parameters of psychological literature, the search for the expression of the characters’ solitude in the midst of the difficulties in their environment offers us an intimate tension within a wide scope of situations. As a general rule, Isabel-Clara Simó focuses her stories mainly on denouncing situations of women’s oppression. In her book, La salvatge (1994) and Dones (1999), the author introduces the image of current urban women where they are depicted as victims of their partners
De la perifèria al centre: reflexions sobre la llengua catalana de l’escriptora Isabel-Clara Simó
No full textL’article presenta una revisió de les principals reflexions sobre la llengua catalana que l’escriptora Isabel-Clara Simó ha realitzat en diversos textos de caire periodístic i assagístic. L’autora defensa un espai lingüístic comú a tots els territoris que parlen la mateixa llengua i realitza una denúncia decidida per a tots els entrebancs que s’hi generen en la normalització de l’ús social de la llengua.The article presents a review of the main reflections on the Catalan language that the writer Isabel-Clara Simó has done in various journalistic and essayistic texts. The author defends a common linguistic area in all the territories that speak the same language and makes a determined denunciation for all the obstacles that are generated in the normalization of the social use of the language
De la perifèria al centre: reflexions sobre la llengua catalana de l’escriptora Isabel-Clara Simó
No full textL’article presenta una revisió de les principals reflexions sobre la llengua catalana que l’escriptora Isabel-Clara Simó ha realitzat en diversos textos de caire periodístic i assagístic. L’autora defensa un espai lingüístic comú a tots els territoris que parlen la mateixa llengua i realitza una denúncia decidida per a tots els entrebancs que s’hi generen en la normalització de l’ús social de la llengua.The article presents a review of the main reflections on the Catalan language that the writer Isabel-Clara Simó has done in various journalistic and essayistic texts. The author defends a common linguistic area in all the territories that speak the same language and makes a determined denunciation for all the obstacles that are generated in the normalization of the social use of the language
Abstract 4784: Effect of epigenetic drugs on chromatin remodeling complexes disrupted in cancer
No full textBarcelona conference on epigenetics and cancer: 50 years of histone acetylation
No full textThe Barcelona Conference on Epigenetics and Cancer (BCEC) was held in Barcelona, Spain, on October 1 and 2 , 2014. The meeting was co-organized by the Cancer Epigenetics and Biology Program (PEBC-IDIBELL) and B·Debate, an initiative of Biocat, with the support of 'la Caixa' Foundation. The scientific committee was comprised of leading scientists in the field of epigenetics: Dr. Manel Esteller, director of PEBC-IDIBELL, Dr. Alejandro Vaquero and Dr. Esteban Ballestar, from PEBC-IDIBELL, Juan Ausió from the University of Victoria (Canada), and Marcus Buschbeck, from the Institute of Predictive and Personalized Medicine of Cancer (IMPPC), as BCEC series coordinator. This meeting was the second edition of the BCEC series, which was launched by 5 leading Barcelonan institutes to bring together leading investigators in the fields of epigenetics and chromatin research. The topics discussed during the meeting included the current challenges, opportunities, and perspectives surrounding the study of histone modifications (focusing in acetylation), chromatin structure and gene expression, and the involvement of histone acetylation in physiology and diseases, such as cancer or neurological diseases
Barcelona conference on epigenetics and cancer: 50 years of histone acetylation
No full textThe Barcelona Conference on Epigenetics and Cancer (BCEC) was held in Barcelona, Spain, on October 1 and 2 , 2014. The meeting was co-organized by the Cancer Epigenetics and Biology Program (PEBC-IDIBELL) and B·Debate, an initiative of Biocat, with the support of 'la Caixa' Foundation. The scientific committee was comprised of leading scientists in the field of epigenetics: Dr. Manel Esteller, director of PEBC-IDIBELL, Dr. Alejandro Vaquero and Dr. Esteban Ballestar, from PEBC-IDIBELL, Juan Ausió from the University of Victoria (Canada), and Marcus Buschbeck, from the Institute of Predictive and Personalized Medicine of Cancer (IMPPC), as BCEC series coordinator. This meeting was the second edition of the BCEC series, which was launched by 5 leading Barcelonan institutes to bring together leading investigators in the fields of epigenetics and chromatin research. The topics discussed during the meeting included the current challenges, opportunities, and perspectives surrounding the study of histone modifications (focusing in acetylation), chromatin structure and gene expression, and the involvement of histone acetylation in physiology and diseases, such as cancer or neurological diseases
La narrativa breu d’Isabel-Clara Simó: a propòsit d’uns contes inèdits
No full textLa carrière littéraire d'Isabel-Clara Simó (1943-2020) s’est essentiellement développée dans les genres narratifs. Ainsi, elle alterne l'écriture et la publication de romans et de nouvelles. C'est dans ce sous-genre que nous voulons concentrer notre analyse, et c'est dans les nouvelles, probablement en raison de leur brièveté, qu’elle offre une grande expérimentation stylistique et thématique ensuite déployée dans les romans. L'autrice expérimente dans divers sous-genres et styles, ce qui nous amène à trouver une grande hétérogénéité structurelle dans ses textes. Cependant, on peut souligner un fait commun qui est l'importance qu’elle accorde au traitement des voix narratives comme reflet de la réalité dans laquelle évoluent les personnages. Nous nous concentrons sur plusieurs nouvelles inédites que nous avons pu consulter par le biais de la famille. Nous analysons également la dernière des publications d’Isabel-Clara Simó, le volume Prime Time. Irrévérences (2019), qui pour diverses raisons n'a pas été distribué dans les circuits commerciaux. Des textes fondamentaux pour comprendre l'évolution de sa stylistique et la diversité de ses thèmes, avec une volonté permanente d'expérimentation.The literary career of Isabel-Clara Simó (1943-2020) has been developed mainly in the narrative genres. Thus, she alternated between writing and publishing novels and short stories. It is in this sub-genre where we want to focus our analysis, as it was in these, probably due to its brevity, that she offered greater samples of stylistic and thematic experimentation that she later deployed in the novels. The author experiments in various sub-genres and styles, which lead us to find a great structural heterogeneity in her texts. However, a common fact can stand out which is the importance that the author attaches to the treatment of narrative voices as a reflection of the reality in which the characters evolve. In our research we focus on several short stories that the author left unpublished and that, through the family, we were able to consult. We also analyse the last of her publications, the volume Prime Time. Irreverences (2019), which for various reasons has not been distributed in commercial channels. Fundamental texts to understand the evolution –with the permanent will to experiment– of her stylistics and the diversity of her themes
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