1,720,984 research outputs found

    Management of large prostatic abscess associated with urethral stenosis and penile cancer recurrence.

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    INTRODUCTION: The purpose of this report was to analyze the management of a large prostatic abscess in a patient with urethral stenosis and recurrence of penile cancer, who had presented with acute urinary retention. METHODS: The clinical diagnosis was based on the end-fire transrectal ultrasound (TRUS) findings and later confirmed by CT. The patient had several surgical scars and radiation-induced effects in the lower abdomen, therefore the placement of a percutaneous sovrapubic catheter was considered hazardous. The placement of a transurethral catheter was impossible because of firm meatal stenosis due to previous penile partial amputation and growing tissue that suggested local recurrence of penile cancer. RESULTS: Transurethral placement of a 8 Fr catheter was possible under radiologic/ultrasound control using a hydrophilic glidewire. The definitive treatment also included percutaneous transperineal drainage and placement of a 8 Fr pig-tail drain under TRUS. Subsequent surgical treatment of the penis showed low grade superficial squamous cell carcinoma. Management and follow-up of prostatic abscess is based on TRUS imaging. After 4 years of follow-up, abscess recurrence was observed and treated with a urethral catheter and antibiotics. CONCLUSION: Urethral stenosis due to penile cancer is a predisposing factor in the development of prostatic abscesses. Placement of a bladder catheter and percutaneous drainage of the abscess are the mainstays of treatment. In malignant urethral stenosis, the conservative management of a prostatic abscess is safe and efficacious in a long-term follow-up. Transrectal US is a key instrument to guide intervention and to check results

    Specimen orientation by marking the peripheral end: (potential) clinical advantages in prostate biopsy.

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    The aim of this paper is to identify advantages that could be obtained by orientation of the biopsy specimen using the marking technique. We reviewed our experience (4,500 cases) and the published literature. The peripheral (proximal) end of the fresh specimen is marked with ink soon after needle delivering in a few minutes. It is performed easily in association with pre-embedding method. Five potential clinical advantages were identified: (1) tumor localization, (2) atypical lesions localization and planning rebiopsy strategy, (3) planning surgical strategy, (4) selection criteria for focal therapy and active surveillance, and (5) cost reduction. Peripheral end marking is low cost, easy and reproducible. It drives several potential advantages in cancer diagnosis or isolated atypical lesions, in particular, spatial localization within the biopsy (transition versus peripheral zone, anterior versus posterior, subcapsular versus intraparenchima, and extraprostatic extension) should be easy and reliable. We can add a new pathological parameter: pathological orientation or biopsy polarity

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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