48,934 research outputs found
Unusual EEG pattern linked to chromosome 3p in a family with idiopathic generalized epilepsy.
No full textOBJECTIVE: To map the gene causing an unusual EEG pattern of delta bursts that appears to segregate as an autosomal dominant trait in an Italian family. The EEG pattern was observed in four family members affected by idiopathic generalized epilepsy (IGE) and in six other clinically unaffected members. METHODS: All available family members underwent clinical and EEG examination. DNA samples were obtained and used to perform a whole-genome scan with 270 microsatellite markers. After the first linked marker was identified, 12 additional markers in the same chromosomal region were tested to confirm linkage and define a candidate interval. RESULTS: The gene responsible for the EEG trait was mapped to an 11-cM interval on the proximal short arm of chromosome 3 (3p14.2-p12.1). CONCLUSION: In this family, a characteristic EEG activity is due to the effect of a single gene on chromosome 3p. A gene encoding a Ca2+ channel subunit maps in the interval and is a potential candidate for the trait. The clinical expression of epilepsy in four family members may reflect the interaction of additional genes, though environmental or other factors cannot be excluded.Journal ArticleResearch Support, Non-U.S. Gov'tinfo:eu-repo/semantics/publishe
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Conceptualization of a real-time information processing platform for context-aware informing cyber-physical systems
No full textInforming cyber-physical systems (I-CPSs) are designed to accomplish sensing, reasoning and informing activities in dynamic context. In order tosimplify and accelerate the design and implementation process of multiple context-aware ICPSs, we are developing an information sensing,computing and actuating (SCA) platform that can be used as a central module of these systems. This paper presents the concept of a SCA platform. Thefunctionality of the platform includes development of context-dependent strategies to adapt the sensing, reasoning and informing behaviors of the platform to various dynamic contexts. There are four constituents of the platform: (1) a generic kernel, (2) built-in elements, (3) add-on components, and (4) system interfaces. The paper also discusses both the internal and external integration mechanism of the SCA platform, which can be customized according to the needs of specific I-CPS applications by extending the generic kernel with various functional built-in elements and add-on components. The feasibility andapplicability of the platform have been tested through a case study: an indoor fire evacuation guiding system. The proposed platform provides a useful package of functionalities, alleviates the burden of developers, and speeds up the development of applications specific context-aware I-CPS.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work publicCyber-Physical System
Genuine memoirs of the celebrated Miss Maria Brown [electronic resource] : Exhibiting the life of a courtezan, in the most fashionable scenes of dissipation. Published by the author of a W** of P*** In two volumes.
No full textAuthor of a W** of P*** [Woman of Pleasure] = John Cleland, to whom this work is sometimes attributed.Electronic reproduction.English Short Title Catalog,Reproduction of original from British Library
Determination of linkage disequilibrium region suggests association of the ancient haplotype, hX with neural function
No full textModern human populations are known to contain "ancient haplotypes" that originated from archaic humans by hybridization. Some of them had been reported before the development of human genomic diversity databases, such as HapMap. Consequently, some of them have no information about linkage disequilibrium (LD) regions. Because genetic information within LD is tightly linked, to know LD region containing ancient haplotypes will be useful to estimate basic parameters of admixture events, and to infer biological functions that linked with the ancient haplotypes. One of these ancient haplotypes, haplotype X (_hX_) was found in a 10.1 kb-region located on Xp11.22, which diverged at 1.4 M years ago, with low diversity within the cluster in gene genealogy and worldwide distribution in low frequency. We determined the LD region around the ancient haplotypes using LD information obtained in the HapMap project. The LD determination presents that the LD region surrounding the _hX_ is stable and contains genic regions that may associate with neural and brain functions
Riprap Stability Model Tests
No full textI. Introduction and Background 11. Test Setup and Conditions 111. Presentation of Data IV. Results V. Conclusions Appendices 1. Definition of Terms 2. Photographs of Model Dike Section 3. Model Riprap Stone Analysis 4. Tables of Expected Percent Damage for Armor Stone with Unit WeightsKWP-collectio
Zaleznosci miedzy stosunkami skladnikow nawozowych i stosunkami pierwiastkow w glebie oraz produktywnoscia agrosystemu
No full textCelem badań było określenie zależności między stosunkami składników nawozowych w nawożeniu substancją organiczną i azotem oraz stosunkami pierwiastków w glebie a produktywnością agrosystemu. Czynnikami doświadczenia były dwa zmianowania, obornik stosowany był w ilości 0, 40 i 80 t·ha⁻¹ co 4 lata, a nawożenie azotem stosowane było w dawkach 0, 40, 80 i 120 kg N·ha⁻¹ na rok. Znamienny wpływ na produktywność agrosystemu miały stosunki składników nawozowych w nawożeniu C/N; N/P; N/K i P/K. Stosunki pierwiastków w glebie C/Fe; N/Mn; P/Mn; S/Mn i Fe/Mn miały istotny związek z produktywnością agrosystemu. W chemiczno-rolniczej interpretacji wpływu nawożenia na produktywność agrosystemu należałoby uwzględniać nie tylko ilości stosowanych nawozów lub dawki składników nawozowych, ale także stosunki składników nawozowych w nawożeniu oraz stosunki pierwiastków w glebie.The aim of study was to determine the relationships between fertilizing component ratios and element ratios in soil and agrosystem productivity in a field experiment. The experimental factors were two crop rotations, farmyard manure application ot 0, 40 and 80 t·ha⁻¹ for every 4 years, and nitrogen fertilization at rates of 0, 40, 80, and 120 kg N·ha⁻¹ annually. Significant effect on productivity of agrosystem showed fertilizing component ratios C/N, N/P, N/K and P/K. Element ratios in soil C/Fe; N/Mn; P/Mn; S/Mn and Fe/Mn were significantly related to agrosystem productivity. In chemical interpretation of agrosystem productivity as affected by fertilization not only the amount of fertilizers or fertilizing component application rate should be taken into consideration but the fertilizing component ratios in fertilization and the element ratios in soil, too
La chronique perdue de Gerard Labuda vue par Władysław Sobociński
No full textZadanie pt. „Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki” nr 885/P-DUN/2014 dofinansowane zostało ze środków MNiSW w ramach działalności upowszechniającej naukę
Three-dimensional structure of quantized vortices in rotating Bose-Einstein condensates
No full textBose-Einstein condensates (BEC) are ideal superfluid systems to realize quantum turbulence (QT): vortex cores in BECs are larger than in superfluid Helium, making easier their observation. Recent experimental and numerical studies reported that vortex states in BEC can evolve towards a turbulent regime when an oscillatory excitation is applied. We discuss in this work how to accurately prepare initial states with vortices before running numerical simulations of QT based on the Gross-Pitaevskii equation. The case of a dense Abrikosov lattice in a fast rotating BEC is presented. High resolution numerical simulations using parallel computing are used to accurately capture physically important features of the vortices (vortex radius, inter-vortex spacing, vortex density profile)
A 2 h periodic variation in the low-mass X-ray binary Ser X-1
No full textSpectroscopy of the low-mass X-ray binary Ser X-1 using the Gran Telescopio Canarias have revealed a ?2 h periodic variability that is present in the three strongest emission lines. We tentatively interpret this variability as due to orbital motion, making it the first indication of the orbital period of Ser X-1. Together with the fact that the emission lines are remarkably narrow, but still resolved, we show that a main-sequence K dwarf together with a canonical 1.4 M? neutron star gives a good description of the system. In this scenario, the most likely place for the emission lines to arise is the accretion disc, instead of a localized region in the binary (such as the irradiated surface or the stream-impact point), and their narrowness is due instead to the low inclination (?10°) of Ser X-1
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