4,556 research outputs found
Exploring the coupling between electron transfer and protein dynamics in photosynthetic reaction centers embedded into dehydrated amorphous matrices
No full textThe interplay between protein dynamics and electron transfer (ET)
has been extensively investigated in the bacterial photosynthetic reaction
center (RC) from Rhodobacter sphaeroides by hampering RC internal
motions at low temperatures [1]. Alternatively, the RC dynamics can
be inhibited at room temperature by incorporating the RC into
dehydrated trehalose matrices [2]. In the glasses the recombination
kinetics of the charge separated state P+QA
are accelerated and
distributed in rate as compared to solution, mimicking at room
temperature the effects observed at 10 K in water-glycerol. This is
taken to indicate inhibition of the RC relaxation from the dark- to the
light-adapted conformation, as well as of the RC thermal fluctuations
[1,2]. We proposed that the inhibition is mediated by residual water
molecules of the RC hydration shell which bridge protein surface
groups with trehalose molecules of the matrix by forming a network
of multiple hydrogen bonds [3]. Consistently, similar effects have
been observed also in RC films dehydrated in the absence of sugar [4].
However, striking differences are found between RC-trehalose glasses
and RC-films: (a) The thermal stability of the RC is tremendously
enhanced in the trehalose matrix. (b) In RC-trehalose matrices, the
P+QA
recombination after a few seconds of continuous photoexcitation
is only partially decelerated as compared to the one recorded
after a laser flash, whereas in dried RC films a comparable period of
continuous illumination leads to a total recovery of the kinetics
observed in the hydrated system. These data indicate that in films the
protein dynamics can be easily regained, in contrast to trehalose
glasses, which reveal much stronger structural constraints. We are
extending these studies to a series of RC mutants characterized by
a widely altered P+/P midpoint potential relative to wild-type [5].
In these mutants, the acceleration of P+QA
recombination induced
by cooling to 10 K in the dark decreased with increasing midpoint
potential [6]. Interestingly, incorporation into dehydrated trehalose
matrices causes instead acceleration of the kinetics by the same factor
for all P+/P midpoint potential values
Static and dynamic aspects of DNA charge transfer: a theoretical perspective
No full textIn this work, we approach the impact of dynamic and static disorder on DNA charge transfer from a theoretical and numerical perspective. Disordered or defect geometries are either realized via molecular dynamics simulations using a classical force field or by experimentally determined DNA bulge structures. We apply a chemically specific, atomically resolved extended Su-Schrieffer-Heeger model to compute the energy parameters relevant to DNA charge transfer. For both models studied here, the effective donor-acceptor couplings-and hence the charge transfer rates-significantly depend upon the geometry. Dynamic disorder leads to a correlation time in this quantity of the order of 30 fs, and the transfer rates universally exhibit a broad, yet well-defined, exponential distribution. For DNA bulges, the angle characterizing the defect controls the charge transfer efficiency. The results are discussed and extensively compared to experimental findings and other calculations
Stylos kai edraiōma tēs ekklēsias, sive, Dissertatio de iustificatione hominis
No full textquam ... sub praesidio ... Ioh. Henrici Heideggeri ... placido eruditorum examini subiicit Andreas Steinerus, Vitod. author & respondens, ad diem Octobris loco horisque solitisDiss. Hohe Schule Zürich, 167
Author: Andreas Johannis Prytz
No full textAn edition of the consecration sermons in Gothenburg Cathedral 1633 by Superintendent Andreas Johannis Prytz, with introductory comments. The first sermon deals with the need for Church buildings, the second with the consecration of a new Church
We must combine conservation of nature with benefits to society. Interview by Gaby Allheilig with Andreas Heinimann on IPBES' Global Assessment Report on Biodiversity and Ecosystem Services
No full textOn 6 May 2019, the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) presented its report on the state of biodiversity and ecosystem services worldwide. The first such assessment since 2005, it concludes that biodiversity and ecosystem loss has reached the point where it threatens human well-being. The researchers involved recommend several urgent measures to political decision-makers. Andreas Heinimann of CDE was the one Swiss scientist who worked as a lead author on a chapter of the report
To athanaton tēs psychēs, sive, Dissertatio de animae immortalitate, ex naturae & sanae rationis lumine demonstrata
No full textquam ... sub praesidio ... Iohannis Lavateri ... publicae ac placidae disquisitioni submittit Andreas Steinerus, Vitod. author & respondens ...Dedikation an Johannes Lavater, Jacob Meyer, Joh. Jacob Schaedler und Jacob Hegner auf dem Titelbl. versoDiss. Hohe Schule Zürich, 167
Family Virtues and Social Critique: Andreas Latzko’s Anti-War Prose (1917-1918)
No full textBetween 1917 and 1918, the Austro-Hungarian author Andreas Latzko (1876-1943) wrote three separate publications against the Great War: Menschen im Krieg (1917), Friedensgericht (1918), and Der letzte Mann (published 1919). Literary historians tend to bypass these works, and the few who note them chiefly focus on the best-selling novella cycle Menschen im Krieg (1917). It is usually presented as an example of expressionist political prose, or as a mixture of social satire and aesthetic shock-tactics that chiefly remains indebted to realist traditions, albeit with occasional incursions into expressionistic styles..
Short laws for finite groups and residual finiteness growth
No full text We prove that for every n ∈ N n \in \mathbb {N} and δ > 0 \delta >0 there exists a word w n ∈ F 2 w_n \in F_2 of length O ( n 2 / 3 log ( n ) 3 + δ ) O(n^{2/3} \log (n)^{3+\delta }) which is a law for every finite group of order at most n n . This improves upon the main result of Andreas Thom [Israel J. Math. 219 (2017), pp. 469–478] by the second named author. As an application we prove a new lower bound on the residual finiteness growth of non-abelian free groups. </p
Value quantification
No full textThis chapter explores the concept and practice of value quantification, emphasizing its crucial role in effectively communicating product offerings in industrial markets. Rather than relying solely on product characteristics, successful sales strategies involve translating unique selling points into quantifiable customer-specific economic value. The chapter synthesizes existing marketing and pricing literature, presenting a comprehensive model that categorizes benefits and sacrifices into quantitative and qualitative dimensions relevant to both B2B and B2C contexts. The author delineates a systematic approach for quantifying customer value, highlighting practical methodologies such as economic value analysis and conjoint analysis. Furthermore, the chapter underscores the managerial implications of value quantification, including enhanced pricing strategies, improved negotiation positions, reduced discounting, and performance-based pricing opportunities. Through detailed frameworks and real-world examples, the chapter provides actionable insights for effectively leveraging quantified value to gain competitive advantage and drive customer purchasing decisions
Sammlung von Merckwürdigkeiten der Natur und Alterthümern des Erdbodens, welche petrificirte Cörper enthält / aufgewiesen und beschrieben von Georg Wolffgang Knorr
No full textVorlageform des Erscheinungsvermerks: Nürnberg, zu finden bey dem Author. Gedruckt bey Andreas Bieling
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