1,721,154 research outputs found
Assesment of human testicular function by radioimmunoassay of testosterone and dihydrotestosterone in saliva
No full textApplication des techniques de la spectroscopie-laser a la determination de la concentration des Hormones Steroides-Resultats preliminaires
No full textHighly specific polyclonal antisera against estriol: cross-reactivity restriction following affinity chromatography
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Beneficial effect of tibolone on mood, cognition, well-being, and sexuality in menopausal women.
No full textTibolone is a synthetic molecule used extensively for the management of menopausal symptoms, with the proposed additional advantage of enhanced mood and libido. Tibolone, after oral administration, is rapidly converted into 3 major metabolites: 3alpha-hydroxytibolone and 3beta-hydroxytibolone, which have estrogenic effects, and the Delta(4)-isomer, which has progestogenic and androgenic effects. The tissue-selective effects of tibolone are the result of metabolism, of enzyme regulation, and of receptor activation which vary in different tissues. Tibolone seems to be effective on estrogen-withdrawal symptoms such as hot flushes, sweating, insomnia, headache, and vaginal dryness, with results generally comparable to the effects exerted by estrogen-based treatments, and the additional property of a progestogenic activity on the endometrium. As well as relieving vasomotor symptoms, tibolone has positive effects on sexual well-being and mood, and improves dyspareunia and libido. These effects may depend on both estrogenic and androgenic actions exerted at the genital level and in the central nervous system, and on a reduction of sex-hormone-binding globulin and an increase of free testosterone, without affecting Delta-5 androgens levels. Based on the evidence available, tibolone is a valuable treatment option to relieve menopausal complaints, especially in women suffering persistent fatigue, blunted motivation, and loss of sexual desire despite an adequate estrogen replacement
Raloxifene treatment increases plasma levels of beta-endorphin in postmenopausal women: a randomized, placebo-controlled study.
No full textAbstract
OBJECTIVE:
To evaluate the effect of the selective estrogen receptor modulator raloxifene hydrochloride (Evista, Eli Lilly and Company, Indianapolis, IN) on plasma levels of beta-endorphin, and to determine whether beta-endorphin levels and menopausal symptoms are related.
DESIGN:
A randomized, double-blind, placebo-controlled pilot study.
SETTING:
Endocrinology outpatient department.
PATIENT(S):
Forty postmenopausal women.
INTERVENTION(S):
The women received raloxifene, 60 mg/d, or placebo for 3 months. A questionnaire on climacteric symptoms was administered before and after treatment.
MAIN OUTCOME MEASURE(S):
Circulating levels of beta-endorphin, climacteric symptom score, and correlation with beta-endorphin levels.
RESULT(S):
Raloxifene treatment significantly increased levels of beta-endorphin and did not significantly affect climacteric symptoms, with the exception of worsening vasomotor symptoms. No significant relation was seen between plasma levels of beta-endorphin and climacteric symptoms.
CONCLUSION(S):
Raloxifene modulates plasma levels of beta-endorphin without concomitantly relieving climacteric symptoms, as seen with hormone replacement therapy
PROPOSTA DI SCHEDA PER LA CARATTERIZZAZIONE DELLE CAVITÀ SOTTERRANEE: CENSIMENTO, ANALISI DEI FENOMENI DI DISSESTO E VALUTAZIONE DEL RISCHIO RESIDUO
No full textNel territorio italiano numerose sono cavità
sotterranee di origine naturale e antropica,
attribuibili a diverse tipologie: cavità carsiche,
cave, catacombe, reti idrauliche, frantoi ipogei,
chiese rupestri, ecc. Ancora molte di queste cavità
appaiono, ad oggi, sconosciute e il numero di quelle
censite è in costante aumento, sia per il continuo
aggiornamento dei database, sia per il frequente
verificarsi di dissesti che le portano alla luce.
Numerose associazioni, enti e istituti si occupano
della raccolta dei dati che caratterizzano le cavità
sotterranee, nel caso di fenomeni di dissesto e nel
caso di stabilità, al fine di catalogazione e censimento.
Infatti, in letteratura si rinvengono svariate e valide
schede che permettono, attraverso check list e campi
predefiniti, la raccolta di informazioni qualitative e,
spesso, anche quantitative. Conseguentemente, gli
Enti preposti al governo del territorio (Comuni,
Regione, Autorità di Bacino, Dipartimento della
Protezione Civile) si ritrovano a confrontare schede
e, quindi, dati, recuperati con finalità differenti
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