10,522 research outputs found

    Electrochemical sensing: innovative devices and methodologies for the analyses of drugs of abuse

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    Chemical sensors are compact, inexpensive and easy-to-use measuring devices that quickly provide the desired analytical response and find application in many fields, such as agriculture, security, industry and others. In this context, my PhD project will focus on the development of electrochemical-type sensors for the identification of the active ingredients present in some of the most common drugs of abuse like cannabinoids, opioids and new psychoactive substances such as synthetic cannabinoids and synthetic opioids. The work will be in collaboration with the Toxicology Laboratory of the Forensic Institute of the Department of Biomedical, Metabolic and Neural Sciences of the University of Modena and Reggio Emilia. In the last decade, the trafficking and use of illicit drugs showed a continuous incremental trend, remaining worldwide a challenging problem for the consequences on society, health, criminality, and environment. Psychotropic effects promoted by drug consumption indirectly affect the population in terms of increasing number of accidents due to reduced driving ability, drug-related crimes and violence, drug-facilitated sexual assaults, spreading of infectious diseases, etc. [1]. Many of the active ingredients of these abuse drugs are electro-active and therefore research and development of electrochemical sensors capable of detecting them can certainly make an important contribution to all organisations working to control and reduce these problems worldwide. Once one or more types of matrices, essentially plant-based or synthetic, have been selected for the determination of the active ingredients, the working methodology will be the one represented in Figure 1. Different electrodic materials will be investigated as the sensing element to promote selectivity and sensitivity. In this regard, carbon-based electrodes, which have proven to be particularly effective for the analysis of cannabinoids, will be initially tested. Then, MIP (Molecular Imprinted Polymers) deposited on quartz crystal microbalances will be explored to combine electrochemical and gravimetric sensing. An additional step of the process will be the use of multivariate analysis methods for the interpretation of the articulated analytical signal that could be obtained when working in complex real matrices. This approach will potentially provide information on both the detection and quantification of the active ingredients under analysis

    Correspondence: Laura Kephart and Arthur Stupka

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    This 1936 correspondence, between Laura Kephart (Mrs. Horace Kephart) and Arthur Stupka, concerns a possible Kephart Memorial. Horace Kephart (1862-1931) was a noted naturalist, woodsman, journalist, and author and promoter of the Great Smoky Mountains National Park. Arthur Stupka (1905-1999) was the first park naturalist to work at the Great Smoky Mountains National Park

    Mindscapes: Laura Riding's poetry and poetics /

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    Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão.Esta tese propõe uma leitura revisionista da poesia contemporânea através do exame do caso de um dos mais esquecidos escritores norte-americanos do século XX: Laura (Riding) Jackson (1901-1991). O objetivo é demonstrar que Riding não apenas possuía uma poética definida e singular, mas que ela permanece uma das instâncias mais extremas e paradoxais do modernismo anglo-americano, a ponto de Riding abandonar a escrita da poesia em 1938. Recorrendo a conceitos de "formação do cânone" bem como às noções de "discurso" e "função do autor", em Foucault, investigo a construção do cânone da poesia moderna anglo-americana, recuperando o contexto e as circunstâncias da ocultação de Riding. Enquanto cubro os "discursos" poéticos em circulação na primeira metade do século XX-o "imagismo" de Pound, a "dissociação da sensibilidade", "impersonalidade" e "tradição" de Eliot, a "unidade orgância" e "ambigüidade" da Nova Crítica-ofereço um panorama crítico de modernismos alternativos sendo articulados à época. Minha intenção é demonstrar que os poemas de Riding são expressões vigorosas de um escritor para quem "a mente pensando se torna a força ativa do poema", para usar a apta formulação de Charles Bernstein. Entre minhas descobertas sobre as várias e complexas razões que levaram à não-canonização de Riding estão a hegemonia da Nova Crítica, o exílio voluntário de Riding da cena literária (onde são feitas ou desfeitas as reputações), sua recusa em ser antologiada, bem como em ser explicada em termos críticos que não os dela. Todos esses fatores, mais a "dificuldade" de sua poesia, contribuíram para fazer de Riding "a maior poeta esquecida da poesia norte-americana", como escreveu Kenneth Rexroth. Ajudado pelos insights de dois importantes críticos de poesia norte-americana, Charles Bernstein e Marjorie Perloff, defendo que a "poesia da mente" de Riding-onde o que está em jogo é que o que pensamos ser a nossa realidade-representa uma mudança radical no paradigma da poética modernista: de uma poesia centrada na imagem para uma poesia centrada na linguagem. Focalizando a experiência consciente e o tempo duracional do pensamento presente em seus poemas, concluo que as "pensagens" de Riding têm o objetivo preciso de constatar um fato universal: enquanto seres humanos e pensantes, estamos numa condição permanente chamada linguagem

    Letter, Julia Gardiner Tyler to Mrs. Laura Holloway, author of First Ladies, dated September 20, 1869

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    ALS of Julia Gardiner Tyler to Mrs. Laura Holloway, author of First Ladies, dated September 20, 1869, about interviewing other first ladies. ALS.Found in:Mss. 65 T97 Additions, Series 1: Mss. Acc. 1993.19 Addition, 186

    Heritage tourism: a case study of the Laura Ingalls Wilder Heritage Site at Pepin, Wisconsin

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    Plan BMany things must be taken into consideration when developing a heritage tourism site. It can be a wonderful opportunity for the community involved to benefit economically and historically. Heritage tourism can keep alive the heritage and traditions of the communities past. When it is discovered that a heritage site exists, the first step is to consult with the community. A site will not succeed without the acceptance and assistance from the community involved. Once the interest is known, the development process can proceed. After determining that there is a heritage tourism site possibility in their area, a commumity must do research to determine the feasibility of the site, what will make it a success, and how to obtain that success. This study will examine a community with a heritage tourism site that has been successful in developing and maintaining it's site. By conducting this study, other communities seeking information for developing their site will have an example and tool to work with. The site chosen for this study is the Laura Ingalls Wilder site in Pepin, Wisconsin. The town is rich with it's heritage associated with Laura Ingalls Wilder. The development and success for this town will be documented through this study. Laura Ingails Wilder is a perfect choice for examining heritage tourism. The author of many American Pioneer books, she has become famous all over the world. In turn all places that she or her family members lived are or are becoming heritage tourism sites. There are older ones that have been in progress for some years, such as the one in Pepin, and there are ones that are being discovered through the popularity of new books written about Laura's family. These communities would benefi greatly from the information this study will produce. Without the bene-fit of this knowledge communities who are unaccustomed to tourism or the way the other Laura Ingalls Wilder sites operate, may make terrible errors in development, tarnishing the site. This may also reflect badly on the other Laura Ingalls Wilder sites. It is important for new Wilder sites to examine all information and know exactly what they are doing when developing the site. If all the Laura Ingalls Wilder sites can benefit from each other's knowledge and experience it will greatly increase the market for all sites. The more detailed and expansive the sites are about their knowledge and sites to see, the more people are going to want to travel to as many sites as possible, learning all they can about the life of Laura Ingalls Wilder and her family. These sites not only attract Laura Ingalls Wilder fans but all people that are interested in the American Pioneer period of the United States history. This study will provide the knowledge for communities who are developing heritage tourism sites, especially those focusing on Laura Ingalls Wilder. This is a very important study for tourism and especially heritage tourism. When a heritage site is discovered communities run into the barrier of not having the experience and knowledge to develop the site properly. This study will analyze tourism in Pepin, Wisconsin to determine it's successfulness due to the fact that it is a Laura Ingalls Wilder heritage tourism site, and Wfit was developed in a way to provide tourists with a view of Laura Ingalls Wilder's past and the past of many Pioneer Americans. By studying this subject it will allow for many people to benefit. Tourist who are seeking the pleasure of the knowledge of the past, and communities who want to preserve their past and profit from tourism

    Core Journal Lists: Classic Tool, New Relevance

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    Reviews the historical context of core journal lists, current uses in collection assessment, and existing methodologies for creating lists. Outlines two next generation core list projects developing new methodologies and integrating novel information/data sources to improve precision: a national-level core psychology list and the other a local institutional core list for the interdisciplinary field of urban studies and planning. The paper is based on the authors’ panel presentation at the 2009 ACRL National Conference (Seattle, Washington) titled “Core Journal Lists Re-viewed and Re-imagined.”This is an electronic version of an article published in Robin A. Paynter, Rose M. Jackson & Laura Bowering Mullen (2010): Core Journal Lists: Classic Tool, New Relevance, Behavioral & Social Sciences Librarian, 29:1, 15-31. Behavioral & Social Sciences Librarian is available online at: http://www.tandfonline.com, http://dx.doi.org/10.1080/01639260903571096Peer reviewe

    Hypermedia navigation: Differences between spatial cognitive styles

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    Recently, many studies have investigated the role of individual and cognitive differences during Web navigation and Web searching. Despite this interest, no works have considered the role may assume individual differences in real-environment navigation during Web navigation. The aim of this work is to investigate the effect of different spatial cognitive styles: Landmark style (LS), Route style (RS) and Survey style (SS), on Web searching behaviour. In real-environment navigation, having a specific style determines the type of information individuals selected to navigate and orient themselves. We hypothesize that LS individuals are less proficient during Web exploration due to their analytical analysis of the environmental features. Vice versa SS individuals will show high performance on Web exploration for their holistic analysis of the World. We asked 30 College Students (10 LS, 10 RS, 10 SS) to solve three Web information tasks. The spatial cognitive style of participants was assessed through the Spatial Cognitive Style Test, and they were also asked to fill in a questionnaire about their internet and computer use. An ad hoc key-logger program for browsers was used to collect Web behaviour measures. In particular, the measures considered were: search engine tools used (e.g. back button), pages visited and revisited, time spent on information searching, and mouse cursor movements. The results showed significant differences between the spatial cognitive styles: LS seems to use a trial and error strategy in order to obtain the relevant information. Differences also emerged in the distribution of mouse cursor movements during Web navigation

    IATUL 32nd Conference 2011, “Libraries for an Open Environment: Strategies, Technologies and Partnerships,” Warsaw University of Technology, Warsaw, Poland, 29 May-2 June 2011

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    This report provides details recorded from the author's attendance at the IATUL 2011 conference in Warsaw, Poland, May 29-June 2, 2011.This is a post-print version of an article that published in Library Hi Tech News. The published version is available at http://www.emeraldinsight.com/journals.htm?issn=0741-9058&volume=28&issue=8&articleid=1958452&show=abstrac

    IFLA satellite pre-conference: open access to science information: trends, models and strategies for libraries

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    The purpose of this paper is to disseminate information about the IFLA pre-conference in Chania, Crete, Greece on the subject of open access in libraries.This is a post-print version of an article published in Library Hi Tech News. The published version of the article is available at http://www.emeraldinsight.com/journals.htm?issn=0741-9058&volume=27&issue=6/7&articleid=1891644&show=abstrac
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