1,720,974 research outputs found
Comportamento dei linfociti T teofillino-sensibili nell'epatite da virus A, B, non-A,non-B. I.Aspetti metodologici
Comportamento dei linfociti T teofillino-sensibili nell'epatite da virus A, B, non-A,non-B. II. Aspetti applicativi
Effects of HIV superinfection on HBV replication in a chronic HbsAg carrier with liver disease
DETECTION OF HEPATITIS B VIRUS DNA IN SERUM BY SPOT HYBRIDIZATION TECHNIQUE: SENSITIVITY AND SPECIFICITY OF RADIOLABELLED AND BIOTIN-LABELLED PROBES
The detection of serum hepatitis B virus (HBV) DNA in 32 chronic HBsAg carriers was performed by spot hybridization technique using both biotinylated and radiolabeled probes, in order to compare their specificity and sensitivity. Our results show that both assays are specific since neither evidence of cross-hybridization between HBV DNA and sera from patients with chronic non-A, non-B (NANB) hepatitis was found, nor HBV DNA was detected both in patients with chronic anti-HBs/anti-HBc-positive hepatitis and in patients negative for all HBV markers. An agreement between the two assays was observed in 94% of the tested sera. Even though in 5 serum samples (6%) low levels of HBV DNA (0.1-1 pg/100 microliter) remained undetected using the biotin-labeled probe, the lower detection limit of the two assays (0.1 pg of HBV DNA) was the same using purified Dane particles as control. This study indicates that the enzymatic detection of HBV DNA is suitable for routine and rapid monitoring of HBV replication in both HBeAg- and anti-HBe-positive patients, as well as for a semiquantitative analysis of serum HBV DNA
Interazioni virus-ospite nella infezione cronica da virus B dell'epatite: Aspetti virologici e storia naturale
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Hepatitis B core antigen expression in chronic hepatitis B: correlation with serum HBV DNA detected by a biotinylated probe
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