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Reply to “Clopidogrel-aspirin combination for atrial fibrillation: CLAAF is not clear” by Jackson SL et al
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Effect of alpha(1)-adrenoceptor blockade on resting and hyperemic myocardial blood flow in normal humans
No full textIn the present study we aimed to assess the effect of alpha(1)-adrenoceptor blockade on resting and hyperemic myocardial blood flow in normal humans. Myocardial blood flow, at baseline and after dipyridamole, was measured with positron emission tomography and O-15-labeled water in 11 normal volunteers at control and during alpha(1)-blockade with doxazosin. Baseline myocardial blood flow during alpha(1)-blockade was not different from control, whereas coronary resistance was significantly lower (73.48 +/- 18.31 vs. 89.84 +/- 27.96 mmHg . min . ml(-1). g(-1); P < 0.05). After dipyridamole, myocardial blood flow during alpha(1)-blockade was significantly higher (3.50 +/- 0.75 vs. 2.58 +/- 0.54 ml . min(-1). g(-1); P < 0.01) and coronary resistance lower (25.30 +/- 7.37 vs. 33.89 +/- 7.04 mmHg . min . ml(-1). g(-1); P < 0.01) compared with control. In conclusion, in normal humans, dipylidamole-induced increase in myocardial blood flow is limited by alpha(1)-mediated coronary vasoconstriction
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Le politiche di riqualificazione urbana e i quartieri a rischio: significato e caratteristiche
No full textAnalisi delle politiche europee di riqualificazione urbana, in particolare nei contesti francese e inglese
Interventi istituzionali tra vincoli e innovazione: analisi dei servizi che operano allo Stadera
No full textAnalisi della ricerca qualitativa svolta nel quartiere Stadera a Milano focaizzato sulgli interventi dei servizi socio-sanitari
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