112,187 research outputs found
El pasado a la luz del presente y del poder en las comedias históricas de José de Cañizares: algunas calas
No full textUnder the Ciceronian motto historia magistra vitae and in the wake of
the Spanish comedia, a court dramatist who lived between two centuries, José de
Cañizares (1676-1750), in his history plays makes use of past events mingled with
fiction and invention in order to discuss them better and above all to link them to the
political situation of his own time, which was starting with the government of a new
dynasty (the Bourbons) during Philip V’s reign. The corpus selected includes the
“privanza” comedy El picarillo en España, señor de la Gran Canaria (played for the
first time in Madrid’s Teatro de la Cruz in 1716), focused on the conflicts between
king John II of Castile, Álvaro de Luna and the aristocracy of their tormented age,
and full of synchronisms and anachronisms; and El pastelero de Madrigal, rey don
Sebastián fingido, whose plot is set during the time of king Sebastian of Portugal,
after whose death in the battle of Alcazarquivir in 1578 harsh dynasty fights broke
out, ending in 1581, when the country fell under Spanish domain: the play was written
in 1706, while the War of the Spanish Succession was being fought far from
reaching any military and political solution. Other comedies by Cañizares analyzed
are La Poncella de Orleans, composed in cooperation with Antonio de Zamora and
explicitly pro-French: it was composed in 1706 as well, and it was represented for
the first time in Madrid in 1707, in order to celebrate the pregnancy of Maria Luisa
of Savoy, Philip V’s first wife. Finally, La banda de Castilla, y duelo contra sí mismo,
is also considered: a manuscript witness of it, dating back to 1727, is kept in the
BNE (Ms. 16.594). In the present essay, the comedies by Cañizares quoted above
are studied in order to examine both their peculiar treatment of the past facing the
playwright’s present and the author’s mindset swaying between the Baroque and
the EnlightenmentBajo el lema ciceroniano historia magistra vitae, y en la estela de la
comedia clásica, un dramaturgo cortesano y de entresiglos como José de Cañizares
(1676-1750), en sus dramas históricos utiliza los eventos del pasado, mezclados
con la ficción y la invención, con la finalidad de cuestionarlos mejor, y sobre
todo de relacionarlos con la situación política de su tiempo, que con Felipe V se
abría al gobierno de la nueva dinastía de los Borbones. El corpus elegido incluye la
comedia de privanza El picarillo en España, señor de la Gran Canaria (estrenada en
el madrileño Teatro de la Cruz, en 1716), centrada en los conflictos entre Juan II,
Álvaro de Luna y la nobleza de su atormentada época, y cuajada de sincronismos y
anacronismos; y El pastelero de Madrigal, rey don Sebastián fingido, cuya intriga se
coloca en la época del rey don Sebastián de Portugal, tras cuya muerte en la batalla
de Alcazarquivir, en 1578, se desataron encarnizadas luchas dinásticas que finalizaron
en 1581, cuando el país cayó bajo el dominio español: el texto se compuso
en 1706, mientras se estaba combatiendo la Guerra de Sucesión, aún lejos de su
solución militar y política. Otras comedias que se examinan son La Poncella de Orleans,
colaborada con Antonio de Zamora y explícitamente francófila, que también
se escribió en 1706, y se estrenó en Madrid en 1707, para celebrar el embarazo de
la primera esposa de Felipe V, María Luisa de Saboya; y La banda de Castilla, y duelo contra sí mismo, de la que se conserva un testimonio manuscrito del año 1727
en la BNE (Ms. 16.594). En este trabajo, se pretenden analizar las citadas piezas
históricas de Cañizares, con la finalidad de estudiar su peculiar tratamiento del pasado
con vistas al presente, y su mentalidad fronteriza, oscilante entre el Barroco y
la Ilustración
Synchronous and metachronous breast malignancies: A cross-sectional retrospective study and review of the literature
No full textObjective. There is increasing interest in patients with metachronous (MBC) and synchronous breast cancer (SBC). The objective of this study was to evaluate the occurrence and outcome of MBCs and SBCs. Methods. A retrospective study on women operated in our department for breast cancer between 2002 and 2005 was carried out. Patients were divided into three groups: women with MBC, SBC, and unilateral breast cancer (UBC). Moreover, we performed a meta-analysis of the English literature about multiple breast cancers between 2000 and 2011 taking into consideration their prevalence and overall survival (OS). Results. We identified 584 breast cancer patients: 16 women (3%) presented SBC and 40 MBC (7%, second cancer after 72-month follow-up IQR 40-145). Although the meta-analysis showed significant OS differences between MBC or SBC and UBC, we did not observe any significant OS difference among the three groups of our population. Anyway, we found a significant worse disease-free survival in MBC than UBC and a significant higher prevalence of radical surgery in MBC and SBC than UBC. Conclusions. Despite the low prevalence of MBC and SBC, the presence of a long time risk of MBC confirms the crucial role of ipsi- and contralateral mammographies in the postoperative follow-up. © 2014 Ambrogio P. Londero et al
A simple variational derivation of slender rods theory
No full textWe present an asymptotic analysis of the three-dimensional problem for a thin linearly elastic cantilever Ωε = εω × (0, l) as ε goes to zero. By assuming ω simply connected and under suitable assumptions on the given loads, we show that the 3D problem converges in a variational sense to the classical dimensional models for extension, flexure and torsion of slender rods
author-bios-SRD-19-0063.R1 – Supplemental material for The Network Structure of Police Misconduct
No full textSupplemental material, author-bios-SRD-19-0063.R1 for The Network Structure of Police Misconduct by George Wood, Daria Roithmayr and Andrew V. Papachristos in Socius</p
Traducir la publicidad para el turismo: referencias culturales en anuncios españoles e italianos
No full textBorderline breast lesions diagnosed at core needle biopsy: can magnetic resonance mammography rule out associated malignancy? Preliminary results based on 79 surgically excised lesions
No full textThe purpose of this study is to assess whether magnetic resonance mammography (MRM) can exclude associated malignancy in case
of diagnosis of borderline breast lesions (B3) at core needle biopsy (CNB). Retrospective analysis of MRM findings of 79 borderline
breast lesions (26 benign papillomas, 29 radial sclerosing lesions, 6 atypical ductal hyperplasias, 18 lobular neoplasias) diagnosed at CNB
was performed. Lesions were classified as ‘‘non-suspicious’’ or ‘‘suspicious’’ according to Fischer score. These findings were compared to
the results of histological analysis of the excisional specimens. Sensitivity, specificity, positive (PPV) and negative (NPV) predictive values
of MRM in predicting the presence of malignancy were calculated. Out of 24 (30.4%) lesions classified as ‘‘suspicious’’, 8 (33.3%) proved
to be malignant and 16 (66.7%) benign. Among the 55 (69.6%) ‘‘non-suspicious’’ lesions, only 1 (1.8%) was malignant (low-grade ductal
carcinoma in situ), while the remaining 54 (98.2%) proved to be benign. MRM sensitivity, specificity, PPV, and NPV were 88.9%,
77.1%, 33.3%, and 98.2%, respectively. When a borderline lesion is diagnosed on CNB, in case of mild or no enhancement at MRM,
follow-up rather than excisional biopsy might be prompted
Role of ultrasound and sonographically guided core biopsy in the diagnostic evaluation of ductal carcinoma in situ (DCIS) of the breast
No full textPURPOSE: The aim of this study was to evaluate the role of ultrasound (US)-guided core biopsy in the diagnosis of ductal carcinoma in situ (DCIS) and to correlate the histological results on percutaneous biopsy and surgical excision.
MATERIALS AND METHODS: Out of 2,423 consecutive core biopsies performed under US guidance, we evaluated 65 lesions with a histological diagnosis of DCIS. All patients underwent mammography, high-frequency broadband US and percutaneous breast biopsy with a 14-gauge needle and a mean number of five samples (range 4-7 passes). Surgical excision was performed in all cases, and the histological results on the surgical specimen were correlated with those on core biopsy samples. The sonographic features of DCIS lesions were described, comparing pure DCIS (those confirmed by definitive histology) and DCIS with invasive component at surgical excision.
RESULTS: Twenty-seven out of 65 DCIS at core biopsy were found to have an invasive or microinvasive component at surgical excision, leading to rate of histological underestimation of core biopsy of 41.5%. The most frequent sonographic appearances were: (a) mass without microcalcifications (47.4% of pure DCIS, 63% of DCIS with invasive component); (b) mass with microcalcifications (23.7% of pure DCIS, 22% of DCIS with invasive component); (c) isolated microcalcifications (10.5% of pure DCIS); (d) ductal abnormalities (18.4% of pure DCIS, 15% of DCIS with invasive component).
CONCLUSIONS: Due to the high underestimation rate of core biopsy, caution is mandatory in the case of DCIS diagnosis on core biopsy. Although some histological features (such as stromal fibrosis, periductal inflammatory infiltrate, high nuclear grade) can suggest the presence of an invasive component, the sonographic appearance of DCIS cannot be used to predict the cases that are underestimated on US-guided core biopsy. Nevertheless, a sonographically detectable solid component, either inside dilatated ducts or associated with microcalcifications, and a size greater than 20 mm are frequently associated with the presence of an invasive component
Desmoid tumor of the breast: radiologic appearance with a focus on its magnetic resonance features
No full textOutcome of initially only magnetic resonance mammography-detected findings with and without correlate at second-look sonography: distribution according to patient history of breast cancer and lesion size
No full textThe purpose of the study was to evaluate the outcome of initially only magnetic resonance mammography (MRM)-detected breast lesions as a function of radiologic features, history of breast cancer and lesion size. We evaluated core needle biopsy (CNB) (148) and follow-up (25) results of 173 initially only MRM-detected lesions-142 with and 31 without "second-look" correlate, as a function of (1) radiologic features (sonographic correlate, MRI BI-RADS category); (2) history of breast cancer; (3) MRM indication in case of history of breast neoplasm; (4) side and size of synchronous cancer; (5) lesion diameter. (1) Overall malignancy rate was 28.3% (49/173); significantly higher among lesions with a sonographic correlate (46/142), than among those without (3/31) (p=0.014). Frequencies of malignancy for MRI BI-RADS categories 2, 3, 4 and 5, were 0% (0/1), 5.4% (4/73), 26.1% (17/65) and 82.3% (28/34), respectively. (2) Malignancy rate was significantly higher in case of history of breast carcinoma (40/118 versus 9/55; p=0.027); in particular, of 42 MRI BI-RADS category 3 lesions in women with history of breast cancer and of 31 in patients without history, 3 (7%) and 1 (3%) proved to be malignant, respectively (non-significant). (3) Malignancy was more frequent when MRM was performed for pre-operative assessment than for follow-up (30/78 versus 10/40; non-significant). (4) Malignancy rate increased in presence of ipsilateral (19/35 versus 11/43; p=0.018), large (cut-off 6 mm: 30/75 versus 0/3, non-significant; 11 mm: 28/61 versus 2/17, p=0.011; 16 mm: 24/48 versus 6/30, p=0.015; 21 mm: 14/21 versus 16/57, p=0.004) primary tumors. (5) The frequency of malignancy was significantly higher in lesions equal to or larger than 6, 11 and 16 mm, compared with smaller lesions (6 mm: 45/136 versus 4/37, p=0.007; 11 mm: 21/51 versus 28/122, p=0.025; 16 mm: 12/24 versus 37/149, p=0.021). Radiologic features, history of breast cancer and large diameter are associated with high likelihood of malignancy in case of initially only MRM-detected lesions. Nevertheless, biopsy might be spared just for MRI BI-RADS 3 lesions in patients without history of breast carcinoma
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