103,293 research outputs found
La diatesi asmatica
No full textThe authors, on the grounds of the most recent literature, outline the immunopathological situation that is at the base of the asthmatic diathesis in atopic and non atopic patient
Loffredo V., Torromino G., Esposito F., Carboncino A., Cecere A., Mele A., De Leonibus E. "Sex regulates memory capacity"
No full textMemory Capacity (MC) is the number of information maintained in memory. MC is regulated by fronto-striatal dopamine circuit and hippocampus (HP).
Using a modified version of the object recognition task, the DOT/IOT, we have recently showed that adult naïve male mice could discriminate 3,4,6 but not 9 different objects after a 1 min or 24 hrs delay. Moreover, it has been reported that male mice use the HP, as well as humans, to solve the task (Sannino et al 2012, Olivito et al 2014; Sugita et al 2015).
To report sex differences influencing MC, we have challenged 3 months old mice (males and females) with the 6-DOT (highest memory load), testing them at different time points.
We have found that 3 months old female mice properly perform the 6-DOT when tested at 1 min delay (Short Term Memory, STM), but they are impaired when tested 24 hr later (Long Term Memory, LTM). Female mice properly perform the 6-IOT (lowest memory load) independently on the delay.
We hypothesized that the impairment in LTM could reflect sex regulated differences in the use of different neuronal circuits to solve the task. Therefore, we are performing c-fos immunohistochemical analysis as an index of stimuli-induced neuronal activation on the HP and the prefrontal cortex, at different time points after exposing the animals to the 6-DOT. Preliminary data show that female mice, differently from males, do not activate the HP.
Sex-regulated neuronal activation might be relevant to understand the higher impact of dementia in women as compared to men
Recensione a «Dulcis alebat Parthenope». Memorie dell’antico e forme del moderno all’ombra dell’Accademia Pontaniana, a cura di G. Germano - M. Deramaix, Napoli, Paolo Loffredo, 2020, pp. 456
No full textRecensione al vol. «Dulcis alebat Parthenope». Memorie dell’antico e forme del moderno all’ombra dell’Accademia Pontaniana, a cura di G. Germano - M. Deramaix, Napoli, Paolo Loffredo, 2020, pp. 456
La Cassazione e i limiti al diritto di sciopero: il passato a volte ritorna
No full textCommento a Cass. 12.9.2024, n. 24473, ord. in materia di limiti al diritto di sciopero. Nella nota si sostiene che, pur non venendo mai citata – e, anzi, essendo dichiarata apertamente l’adesione all’orientamento opposto, quello assoluta-mente dominante –, la teoria dei limiti interni al diritto di sciopero pare riecheggiare nella motivazione dell’ordinanza in commento
Comparative evaluation of the efficiency of low-cost adsorbents and ligninolytic fungi to remove a combination of xenoestrogens and pesticides from a landfill leachate and abate its phytotoxicity
No full textIn this study, two widely available low-cost adsorbents, almond shells and a green compost, and two ligninolytic fungi, Pleurotus
ostreatus and Stereum hirsutum, were used to remove organic contaminants from a landfill leachate (LLe) and abate its
phytotoxicity. The methodology adopted was based on the occurrence of two simultaneous processes, such as adsorption and
bioremoval. The leachate was artificially contaminated with a mixture of the xenoestrogens bisphenol A (BPA), ethynilestadiol
(EE2) and 4-n-nonylphenol (NP), the herbicide linuron and the insecticide dimethoate at concentrations of 10, 1, 1, 10 and 10 mg
L¡1
, respectively. Three adsorption substrates were prepared: potato dextrose agar alone or the same incorporating each adsorbent.
The substrates were either not inoculated or inoculated with each fungus, separately, before to be superimposed on LLe. After 2
months, the residual amount of each contaminant, the electrical conductivity, the pH and the content of total phenols were measured
in treated LLe. Germination assays using lettuce, ryegrass and radish were performed to evaluate LLe phytotoxicity. The
combination substrateCP. ostreatus showed the best results with average removals of 88, 96, 99, 58 and 46% for BPA, EE2, NP,
linuron and dimethoate, respectively. The same treatment considerably reduced the phenol content in LLe compared to no
treatment. The combination substrateCS. hirsutum produced average removals of 39, 71, 100, 61 and 32% for BPA, EE2, NP,
linuron and dimethoate, respectively. Also uninoculated substrates showed relevant adsorption capacities towards the five
contaminants. Most treatments significantly reduced LLe phytotoxicity, especially on lettuce. The best results were obtained with the
treatment compostCS. hirsutum, which produced root and shoot lengths and seedling biomass of lettuce, respectively, 2.3, 3.3, and
1.9 times those measured in untreated LLe. In general, germination results were negatively correlated with LLe properties like the
residual amount of the contaminants, the electrical conductivity and the pH. These results show that the methodology adopted in the
study, i.e., combined adsorption/biodegradation, is suitable not only to remove xenobiotic contaminants from the leachate but also
to reduce considerably its inhibition on seed germinatio
Società a responsabilità limitata
No full textRassegna biennale di giurisprudenza e dottrina sulla Società a responsabilità limitat
Diritto del lavoro: politiche, memoria e immaginazione. Liber amicorum per Lorenzo Gaeta
No full textSimultaneous removal of endocrine disruptors from a wastewater using white rot fungi and various adsorbents
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