1,720,964 research outputs found
Profilo di sicurezza e tollerabilità.
L’emicrania cronica (EC) è una condizione neurologica disabilitante che si manifesta secondo i criteri classificativi dell’International Headache Society ICHD-II con cefalea di tipo emicranico presente per almeno 15 giorni al mese da più di 3 mesi, in assenza di un uso eccessivo di farmaci. Tra le opzioni terapeutiche profilattiche di secondo livello a disposizione per pazienti resistenti o intolleranti alla terapia di profilassi primaria, vi è la Tossina Botulinica di tipo A (onabotulinum toxin A)
Efficacia, sicurezza e tollerabilità della tossina botulinica A nella profilassi in pazienti con emicrania cronica: studio esplorativo di coorte su 52 pazienti
Conclusioni. Il nostro studio conferma i dati presenti in letteratura, ma allo stesso tempo mette in evidenza come sia necessario studiare ulteriormente l’andamento temporale della risposta terapeutica, soprattutto in pazienti con maggiore severità del disturbo, ed individuare i fattori che possono influenzare tale risposta
INIEZIONE DI TOSSINA BOTULINICA DELL'ARTO SUPERIORE SPASTICO A LIVELLO DI POLSO E DITA IN PAZIENTI CON STROKE CRONICO: UNO STUDIO RANDOMIZZATO CONTROLLATO DI COMPARAZIONE DI TRE DIFFERENTI TECNICHE INIETTIVE
Obiettivo: Comparare l'efficacia di diverse tecniche d'inoculazione della tossina botulinica (palpazione, elettrostimolazione, ecografia) nel paziente con arto superiore spastico. Metodi: 60 pazienti con ictus cronico e spasticità di polso e dita sono stati randomizzati in 3 gruppi. Ognuno ha ricevuto un'iniezione di tossina botulinica in almeno due dei seguenti muscoli: flessore radiale del carpo, flessore superficiale e profondo delle dita. Per eseguire l'inoculo, nel primo gruppo (1) è stata usata la palpazione, nel secondo (2) l'elettrostimolazione, nel terzo (3) l'ecografia. Tutti i pazienti sono stati valutati prima dell'iniezione e a 1 mese. Outcome: Ashworth modificata, Tardieu, pROM di polso e dita. Risultati: ad 1 mese dall'iniezione il punteggio alla Ashworth, alla Tardieu ed il pROM sono migliorati significativamente nel gruppo 3 rispetto al gruppo 1. Nei pazienti del gruppo 2 è migliorata la Ashworth ed il pROM rispetto al gruppo
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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