1,721,072 research outputs found
Obesità e osteoporosi
No full textil capitolo tratta dell'epidemiologia dell'osteoporosi e delle fratture dafragilità nell'obeso e delle correlazioni fisiopatologiche e endocrinometaboliche tra tessuto adiposo e tessuto osseo
Bisphosphonates and osteomyelitis of the jaw: a pathogenic puzzle
No full textThe maxillary and mandibular bones undergo high-turnover remodeling to maintain mechanical competence. Common dental or periodontal diseases can increase local bone turnover. Bisphosphonates (Bps) accumulate almost exclusively in skeletal sites that have active bone remodeling. The maxillary and mandibular bones are preferential sites for accumulation of Bps, which become buried under new layers of bone and remain biologically inactive for a long time. Surgical odontostomatological procedures create open bony wounds that heal quickly and without infection, as a result of activation of osteoclasts and subsequently osteoblasts. Once Bps are removed from the bone via activation of osteoclasts after a tooth extraction or a periodontal procedure, they induce osteoclast apoptosis. This inhibition of osteoclast bone resorption impairs bone wound healing because of decreased production of cytokines derived from the bone matrix, and the bone is exposed to the risk of osteomyelitis and necrosis. The pathogenic relationship between Bps and osteonecrosis of the jaw is unclear, but there is evidence to indicate an association between high-dose BP treatment and exposure to dental infections or oral surgical procedures. A better knowledge of the interactions between Bps and jaw and maxillary bone biology will improve clinical and therapeutic approaches
Career Adaptability and re-employability after long periods of inactivity
No full textThere has recently been an increasing interest in stimulating re-employment of unemployed workers by so-called active labor market policies. In Italy, the Fiat factory in Termini Imerese (Sicily) is one of the most important business cases in the study of the relationship between economic and psycho-social needs of an entire area in relation to the theme of the work importance. This paper is the result of an agreement signed between our University Department, the company interested to reintegrate ex-FIAT workers (BLUTEC), and the consulting firm who have in charge with this delicate transition process. We want to explore the psychosocial variables related to the long period of inactivity, studyng approximately 700 employees who are in this delicate life transition. We decided to assess the degree of Career adaptability defined by Zacher et al. (2015) as a psychosocial resource that can help employees to effectively manage career changes and challenges. The construct of Career Adaptability refers to four different dimensions: concern, control, curiosity, and confidence (Savickas & Porfeli, 2012). Purpose of this paper is to assess how the Career Adaptability of workers, explored through the ladder Career Adapt-Abilities Scale (CAAS - Italian form, Soresi, Note & Ferrari, 2012) is able to predict the employability of workers to the new company, and the role in this process of some personality variables
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