1,721,054 research outputs found
MORPHOLOGICAL OBSERVATIONS ON PANCREATIC-ISLET BLOOD-VESSELS IN LOW-DOSE STREPTOZOCIN-TREATED MICE
No full textThe aim of this study was to observe modifications occurring within the blood vessels of pancreatic islets in low-dose streptozocin (STZ)-treated mice. Forty-two male C57 BL/6J mice were given 40 mg STZ on 5 consecutive days and killed 6 or 10 d after the first STZ injection. Immunocytochemistry revealed a dense accumulation of cells carrying the 7D10 epitope, related to macrophage inhibitor factor, arranged around the 'vascular pole' of the islets on d 6, and a small number of positive cells within the islets on d 10. Many Ia positive cells (equivalent to MHC class II antigen positive elements) were also found at the periphery of the islet. Ultrastructural observations showed the presence of monocytes within almost all the capillary vessels encircling the islets and entering them at the 'vascular pole' (d 6). On d 10 capillary lumina no longer contained marginating monocytes but activated macrophages were seen in the islet parenchyma
Gangliosides prevent insulitis but not islet B cell destruction in low-dose streptozocin-treated mice
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Adhesion molecules and microvascular changes in the nonobese diabetic (NOD) mouse pancreas. An NO-inhibitor (L-NAME) is unable to block adhesion inflammation-induced activation
No full textAppropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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