180 research outputs found
Eugen Simion – insigne la reverul operelor literare
This article refers, on the one hand, to the laborious activity of Eugen Simion in the field of criticism and literary history from his debut until 1989, materialized in the series Romanian Writers of Today (1974-1989), and, on the other hand, aims to reveal the passionate manner in which Eugen Simion was involved, from the date mentioned above, in several visionary projects, among which are the facsimilation of Eminescu’s Notebooks, the Chronology of the Romanian Literary Life (1944-2012), the General Dictionary of Romanian Literature (8 vols) and the coordination of the Fundamental Works collection (also known as the Pléiade Collection) from which over 300 volumes appeared. Last but not least, the author of this article extracts from the work of Eugen Simion a series of memorable quotes, which he considers, in a symbolic way, “badges on the lapel of his books”
EUGEN SIMION: EXEGI MONUMENTUM
This text is a reminder that October marks one year since the passing of Professor Academician Eugen Simion, a prominent figure in Romanian culture. The article pays tribute to the efforts and achievements of Eugen Simion’s work and legacy, exemplified by the verses of the Latin poet Horace, “exegi monumentum aere perennius”. It highlights the significant contributions of this exceptional personality of Romanian culture and literature, emphasising Eugen Simion’s reputation as one of the most esteemed literary critics and historians, essayists and theorists in the field of literature. He is considered the (theoretical) founder of biographical genres (journals, correspondence, memoirs). His activity as an editor, preface writer, author of monographs and promoter of national-scale projects yielded important results, including Dicționarul General al Literaturii Române ‘The General Dictionary of Romanian Literature’ (DGLR, two editions), Cronologia vieții literare românești 1944 – 2012 ‘The Chronology of Romanian Literary Life 1944 – 2012’ (CVLR, 60 volumes) and the facsimile reproduction of Eminescu’s manuscripts (notebooks) (38 volumes). A university professor and member of the Romanian Academy and president of this high forum between 1997 and 2006, Eugen Simion also became a member of seven other academies in the United Kingdom, Denmark, France, Greece, Moldova, Spain and Serbia. Some of his books and studies were translated in Belgium, Switzerland, France, Germany, the United States, Serbia and Hungary. The unexpected loss of Professor Eugen Simion left a vast literary project unfinished, deprived now of the infectious energy and enthusiasm of its initiator. These projects are currently being continued and completed by researchers at the “G. Calinescu” Institute of Literary History and Theory of the Romanian Academy, where Eugen Simion served as director
Controversies on the surgical treatment of patients with Ludwig’s angina
Rezumat.
Flegmonul difuz al planșeului bucal este
un proces infecţios gangrenos, hipertoxic,
care cuprinde spaţiile submandibulare, sublinguale
și spaţiul submentonier, cu tendinţa
de răspândire în spaţiile învecinate. Studiul de
faţă își propune scopul de a face o incursiune/
analiză a literaturii care reflectă tratamentul
chirurgical al flegmoanelor planșeului bucal.
În cadrul studiului, au fost utilizate surse care
conţin informaţii relevante la tema în discuţie,
62 surse în total, dintre care au fost selectate
24. În tratamentul pacienţilor cu flegmon
al planșeului bucal se va respecta cu stricteţe
ordinea priorităţilor: 1) Protejarea căilor respiratorii.
2) Administrarea de antibiotic. 3)
Tratamentul chirurgical. Aceasta este ordinea
manipulărilor prioritare descrisă în cele mai
multe surse. Tratamentul chirurgical va fi
diferit, în funcţie de fiecare pacient în parte.
Inciziile mici prezintă o serie de avantaje, dar
și de dezavantaje, care trebuie luate în calcul
la fiecare intervenţie. Tratamentul complex
al pacienţilor cu flegmon al planșeului bucal
trebuie iniţiat în timpul cel mai scurt posibil.Summary.
Ludwig’s angina is a gangrenous, hypertoxic
infectious process, including submandibular,
sublingual and submental space,
which tends to spread to the surrounding areas.
The purpose of the study is to conduct a
literature reviewon the surgical treatment of
Ludwig’s angina. Topic–related literature was
studiedby using reference sources containing
relevant data. A total amount of 62 sources
wasanalyzed, whereas 24 were selected. The
main priorities in the treatment of patients
with Ludwig’s angina are as following: Airway
protection. Antibiotic administration. Surgical
treatment. This priority order is being
described in a series of sources. The method
of surgical treatment differs, depending on
each individual case. Surgical small incisions
might exhibit a number of both advantages
and disadvantages that should be considered,
prior to each intervention. Patients
with phlegmon of the oral floor should be
subjected to a complex treatment as soon as
possible
Surgical treatment complications to the pacients with infflamatory processes in oromaxilo-facial region
Rezumat.
Pentru realizarea acestui studiu au fost selectati 12 pacienţii cu procese
inflamatorii din sectia de chirurgie oro-maxilo-faciala, la care starea generala si locala s-a agravat cu toate că se aflau sub un tratament complex.
Ne-am propus să observăm situaţiile în care procesele inflamatorii progresează după aplicarea unui tratament complex. În multe cazuri cînd procesele inflamatorii progresează după aplicarea unui tratament complex, sunt
prezente doar manifestările clinice. Adesea leucocitele sunt în scădere, iar
tomografia nu relevă colectii purulente. Pacientul poate prezenta o stare
subfebrilă. Aceste situaţii pot crea confuzii medicului în legătură cu planul
de tratament.Summary.
For this research were selected 12 patients
with inflammatory processes from maxilofacial-surgery section, whose general and local
status were hard affected, although were being
under the complex treatment. Were supposed
to find out the situations of the progressing of
the inflammatory processes after the complex
treatment were applied. A lot of cases of progressing of inflammatory processes after the
complex treatment, are presented just clinical
manifestations. As usually the leukocytes are
being decreased and the computer tomography doesn’t show any pus collections. The
patient can have feverish condition. These
situation can create confusion for the doctor
to appreciate the plan of the following actions
Optimizarea diagnosticului și tratamentului la pacienții cu flegmon al planșeului bucal: Rezumatul tezei de doctor în științe medicale: 323.01 – Stomatologie
Actualitatea și importanța problemei cercetate. Flegmonul planșeului bucal este o
infecție, definită ca o afecțiune inflamatorie bilaterală și rapid progresivă a spațiilor sublinguale,
submandibulare și submentonier. Maladia reprezintă o urgență medicală, care se manifestă, de
obicei, prin indurație consistentă și tumefiere a planșeului bucal, asociată cu risc major de
obstrucție a căilor respiratorii și de extindere a infecției de-a lungul planurilor fasciale în lojele
adiacente și spre mediastin [8, 16].
Din cauza ratei crescute a afecțiunilor comorbide (imunodepresia, diabetul zaharat), care
sunt și factorii de risc majori pentru pacienții cu flegmon al planșeului bucal, incidența acestei
afecțiuni este în creștere. Deși afecțiunea este rară, rămâne încă a fi o maladie importantă care
poate pune viața în pericol, în primul rând, din cauza obstrucției căilor respiratorii [1, 2]. În circa
90% din cazuri, flegmonul planșeului bucal este de origine odontogenă, dinții 7 și 8 inferiori
constituind 70-80% [2, 7].
Protecția căilor respiratorii și terapia medicamentoasă antiinflamatorie și antibacteriană,
instituită timpuriu, prezintă rezultate favorabile. Cu toate acestea, intervenția chirurgicală care
implică drenajul adecvat al colecțiilor purulente, debridarea țesutului necrotic până la limita
ţesuturilor clinic sănătoase și lavaje cu soluții antiseptice este esențială. Pe lângă avantaje, metoda
clasică de tratament chirurgical are și unele dezavantaje: gradul înalt de agresivitate chirurgicală;
acoperirea rapidă a plăgii cu fibrină, ceea ce împiedică drenarea eliminărilor purulente; regenerare
dificilă a țesuturilor; cicatrici postoperatorii voluminoase și inestetice [4, 9].
Astfel, rezultatele analizei literaturii de specialitate și experiența clinicii noastre
argumentează oportunitatea elaborării unui nou concept/protocol de intervenție chirurgicală
minim-invazivă al flegmonului planșeului bucal, care ar contribui la reabilitarea timpurie, efectivă
și mai puțin traumatică. În acest sens, este important de selectat strategia intervențională
corespunzătoare, care ține cont de particularitățile individuale ale pacientului [12, 13] [....]
Optimizing the diagnosis and treatment in patients with oral floor phlegmon
Actualitatea și importanța problemei cercetate. Flegmonul planșeului bucal este o
infecție, definită ca o afecțiune inflamatorie bilaterală și rapid progresivă a spațiilor sublinguale,
submandibulare și submentonier. Maladia reprezintă o urgență medicală, care se manifestă, de
obicei, prin indurație consistentă și tumefiere a planșeului bucal, asociată cu risc major de
obstrucție a căilor respiratorii și de extindere a infecției de-a lungul planurilor fasciale în lojele
adiacente și spre mediastin [8, 16].
Din cauza ratei crescute a afecțiunilor comorbide (imunodepresia, diabetul zaharat), care
sunt și factorii de risc majori pentru pacienții cu flegmon al planșeului bucal, incidența acestei
afecțiuni este în creștere. Deși afecțiunea este rară, rămâne încă a fi o maladie importantă care
poate pune viața în pericol, în primul rând, din cauza obstrucției căilor respiratorii [1, 2]. În circa
90% din cazuri, flegmonul planșeului bucal este de origine odontogenă, dinții 7 și 8 inferiori
constituind 70-80% [2, 7].
Protecția căilor respiratorii și terapia medicamentoasă antiinflamatorie și antibacteriană,
instituită timpuriu, prezintă rezultate favorabile. Cu toate acestea, intervenția chirurgicală care
implică drenajul adecvat al colecțiilor purulente, debridarea țesutului necrotic până la limita
ţesuturilor clinic sănătoase și lavaje cu soluții antiseptice este esențială. Pe lângă avantaje, metoda
clasică de tratament chirurgical are și unele dezavantaje: gradul înalt de agresivitate chirurgicală;
acoperirea rapidă a plăgii cu fibrină, ceea ce împiedică drenarea eliminărilor purulente; regenerare
dificilă a țesuturilor; cicatrici postoperatorii voluminoase și inestetice [4, 9].
Astfel, rezultatele analizei literaturii de specialitate și experiența clinicii noastre
argumentează oportunitatea elaborării unui nou concept/protocol de intervenție chirurgicală
minim-invazivă al flegmonului planșeului bucal, care ar contribui la reabilitarea timpurie, efectivă
și mai puțin traumatică. În acest sens, este important de selectat strategia intervențională
corespunzătoare, care ține cont de particularitățile individuale ale pacientului [12, 13] [....].The relevance and importance of the researched issue. Phlegmon of the oral floor is defined as a bilateral and rapidly progressive inflammatory condition affecting the sublingual, submandibular, and submental spaces. This condition represents a medical emergency typically characterized by firm induration and swelling of the floor of the mouth, accompanied by a high risk of airway compromise and spread of infection along fascial planes into adjacent compartments and towards the mediastinum [8, 16]. Due to the increased incidence of comorbid conditions (such as immunosuppression and diabetes mellitus), which are also major risk factors for the oral floor phlegmon, the incidence of this condition is on the rise. Although the condition is rare, it remains an important disease that can be life-threatening, primarily due to airway obstruction [1, 2]. In approximately 90% of cases, the oral floor phlegmon is of odontogenic origin, with teeth 7 and 8 in the mandible accounting for 70-80% [2, 7]. Respiratory tract protection and early use of anti-inflammatory and antibacterial drug therapy show favorable outcomes. However, surgical intervention involving proper drainage of purulent collections, debridement of necrotic tissue to the limit of clinically healthy tissues, and lavage with antiseptic solutions is essential. Despite its benefits, the traditional surgical treatment approach also comes with some disadvantages: a high level of surgical aggression; rapid wound sealing with fibrin, obstructing the drainage of purulent discharge; challenging tissue regeneration with bulky and cosmetically unappealing postoperative scars [4, 9]. Thus, the findings of the specialized literature analysis and our clinical experience advocate for the opportunity to develop a new concept/protocol for minimally invasive surgical intervention of buccal floor phlegmon, which would contribute to early, effective, and less traumatic rehabilitation. In this regard, it is important to select the appropriate interventional strategy, taking into account the individual characteristics of the patient [12, 13] [....]
Optimizing the diagnosis and treatment in patients with oral floor phlegmon: Summary of Ph.D Thesis in Medical Sciences: 323.01 – Dentistry
The relevance and importance of the researched issue. Phlegmon of the oral floor is
defined as a bilateral and rapidly progressive inflammatory condition affecting the sublingual,
submandibular, and submental spaces. This condition represents a medical emergency typically
characterized by firm induration and swelling of the floor of the mouth, accompanied by a high
risk of airway compromise and spread of infection along fascial planes into adjacent compartments
and towards the mediastinum [8, 16].
Due to the increased incidence of comorbid conditions (such as immunosuppression and
diabetes mellitus), which are also major risk factors for the oral floor phlegmon, the incidence of
this condition is on the rise. Although the condition is rare, it remains an important disease that
can be life-threatening, primarily due to airway obstruction [1, 2]. In approximately 90% of cases,
the oral floor phlegmon is of odontogenic origin, with teeth 7 and 8 in the mandible accounting
for 70-80% [2, 7].
Respiratory tract protection and early use of anti-inflammatory and antibacterial drug
therapy show favorable outcomes. However, surgical intervention involving proper drainage of
purulent collections, debridement of necrotic tissue to the limit of clinically healthy tissues, and
lavage with antiseptic solutions is essential. Despite its benefits, the traditional surgical treatment
approach also comes with some disadvantages: a high level of surgical aggression; rapid wound
sealing with fibrin, obstructing the drainage of purulent discharge; challenging tissue regeneration
with bulky and cosmetically unappealing postoperative scars [4, 9].
Thus, the findings of the specialized literature analysis and our clinical experience advocate
for the opportunity to develop a new concept/protocol for minimally invasive surgical intervention
of buccal floor phlegmon, which would contribute to early, effective, and less traumatic
rehabilitation. In this regard, it is important to select the appropriate interventional strategy, taking
into account the individual characteristics of the patient [12, 13] [....]
Antibioticotherapy used in the treatment of a phlegmon of oral floor
Rezumat
Flegmonul planșeului bucal este o patologie inflamatorie gravă, cu risc
major de răspândire a supuraţiilor în lojele învecinate și spre mediastin.
Pentru evitarea eventualilor complicaţii este necesar ca diagnosticul sa fie
stabilit cât mai timpuriu și de administrat un tratamentul complex. Prima
prioritate în tratament este mereu salvarea vieţii. Tratamentul este orientat
în 3 direcţii: menţinerea respiraţiei; terapie agresivă cu antibiotice; decompresia chirurgicală a spaţiilor submentonier, sublingual și submandibular[6]. Aceasta ne-a determinat să facem o analiză în această direcţie.Summary
The phlegmon of oral of it’s a severe inflammatory disease with a high
risk of spreading of the pus to the adjacent spaces and mediastinum. To
avoid the complications it is necessary to put the earlier diagnosis and indicate the complex treatment of it. The main priority of the treatment is to
save the life of the patient. The treatment is orientated in three directions:
to maintain the breathing, aggressive antibioticotherapy, surgery decompression of the submental, sublingual and submandibular space. It’s determined us to make analyses in this direction
Septicemia as a complication of diffuse phlegmon of the mouth floor
Department of Oral and Maxillofacial
Surgery and Oral Implantology Arsenie Gutan,
Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of MoldovaIntroduction. Despite all the steps made in recent decades in the knowledge of pathogenesis, in
improving diagnosis and therapy of septicemia, this disease, regardless of the age at which it
occurs, is a complex medical problem. We need a multidisciplinary team to solve it, which
besides the infectious disease doctor, microbiologist, biochemist, and radiologist, often requires
specialists in intensive surgery and surgeons of various profiles. Bacteriology of septic shock
records: Gram-negative germs 50-60%, Gram-positive germs 6-24%.
Aim of the study. The assessment of clinical and paraclinical picture in patients with phlegmon
of the mouth floor, complicated with sepsis.
Materials and methods. Analysis of 50 patients who suffered from phlegmon of the mouth
floor, who were hospitalized in the Oral and Maxillo-facial Surgery department of IMSP IMU
Chisinau between the 2016 and 2017 years. Patients were clinically and paraclinically
investigated. Literature analysis of 17 articles, 5 PhD thesis, 3 books.
Results. 6 % of all patients examined with phlegmon of the mouth floor were diagnosed with
sepsis. Approximately two patients diagnosed with oral phlegmon and complications of this
disease die each year in the Republic of Moldova, which accounts for approximately 7% of all
patients with this diagnosis. The untreated septic shock lasts for several hours to 1-2 days, with a
fatal outcome in 30-60% of cases. According to M. Balş, septicemia occurs in people with a
reasonable defense capacity, which is strong enough to fight, develop a local and general
inflammatory process, but insufficient to stop the infection from the beginning. In people with
collapsed defense, the clinical picture of septicemia is not developed, the infection leads to septic
shock violently.
Conclusions. 1. There is an imbalance betweenpro-inflammatory vs anti-inflammatory,
coagulation vs. anti-coagulation, oxidative vs anti-oxidative, apoptotic vs. anti-apoptotic systems
in patients with severe sepsis. 2. Signs and general symptoms of sepsis are fever higher than 38.3
degrees Celsius; hypothermia lower than 36 degrees Celsius; heart rate higher than 90
beats/minute; tachypnea, hyperglycemia 7.7 mmol/l. 3. The cause of over 90% of the deaths of
patients with inflammatory processes in the Oral and Maxillo-facial department is the septic
shock resulting in polyorganic insufficiency
The public law of the Romanians
Title: Dreptul public al românilor (The public law of the Romanians) Originally published: Iaşi, Tip. Tribunei Române, 1867. The work was published posthumously. Language: Romanian The excerpts used are from C. I. Gulian et al., eds., Antologia gîndirii româneşti, sec. xv–xix (Bucharest: Ed. Politică, 1967), vol. I, pp. 380–383. About the author Simion Bărnuţiu [1808, Bocşa Română (Hun. Boksánbánya, Ger. Rumänisch Bokschan, Transylvania) – 1864, Trăznea (Hun. Ördögkút, Ger. Teufelsbrunnen, Tr..
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