1,721,021 research outputs found
Efficacy of the combination ampicillin plus ceftriaxone in the treatment of a case of enterococcal endocarditis due to Enterococcus faecalis highly resistant to gentamicin: Efficacy of the "ex vivo" synergism method
No full textThe case of a patient with highly gentamicin-resistant Enterococcus faecalis endocarditis treated with an ampicillin + ceftriaxone combination is described. We have designed a method to evaluate synergism between the antibacterial activity of patient's serum taken during a given antibiotic regimen (ampicillin) to which another antibiotic (ceftriaxone) is added in vitro. In this patient the two-drug combination was able to stop the bacteremia and prevent the infection of the prosthetic valve
Ex-Vivo synergism: A method for optimizing antimicrobial combinations for difficult-to-treat enterococcal endocarditis
No full textEx-Vivo Synergism: A Method for Optimizing Antimicrobial Combinations for Difficult-To-Treat Enterococcal Endocarditis
No full textBreakthrough Fusarium sp probable pneumonia during fluconazole therapy in an AIDS patient with diabetes, candidemia, Pneumocystis carinii pneumonia and cytomegalovirus disseminated infection
No full textBreakthrough Fusarium sp probable pneumonia during fluconazole therapy in an AIDS patient with diabetes, candidemia, Pneumocystis carinii pneumonia and cytomegalovirus disseminated infection
No full textCaspofungin in combination with itraconazole and amphotericin B for the treatment of invasive aspergillosis in humans, with a method to test ex vivo synergism
No full textEasy synergism for colistin-resistant KPC-producing Klebsiella pneumoniae: the E-test with supplemented agar
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Meropenem-Vaborbactam as Salvage Therapy for Ceftazidime-Avibactam-, Cefiderocol-Resistant ST-512 Klebsiella pneumoniae-Producing KPC-31, a D179Y Variant of KPC-3
Full text linkA 68-year-old man had recurrent bacteremia by Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae resistant to ceftazidime-avibactam and cefiderocol. The sequencing of a target region showed that it harbored a KPC-3 variant enzyme (D179Y; KPC-31), which confers resistance to ceftazidime-avibactam and restores meropenem susceptibility. The patient was successfully treated with meropenem-vaborbactam
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